Anti-alpha-Smooth Muscle Actin antibody (monoclonal)
Mouse IgG monoclonal antibody for ACTA2 detection.
|Immunogen||N-terminal synthetic decapeptide of alpha-smooth muscle actin.|
|Storage||At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.|
|Reactivity||Human, Mouse, Rat|
|Cross Reactivity||No cross reactivity with other proteins|
|Protein Name||Actin, aortic smooth muscle|
|Gene Full Name||actin, alpha 2, smooth muscle, aorta|
|Synonyms||AAT6|ACTSA|MYMY5|ACTSA|alpha-cardiac actin|cell growth-inhibiting gene 46 protein|
|Uniprot ID||Human(P62736), Mouse(P62737), Rat(P62738)|
|Application||IHC-P, IHC-F, WB|
|Ig type||mouse IgG2a|
|Concentration||1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100μg/ml.|
Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
Ueyama et al.(1990) assigned the ACTSA gene to chromosome 10 by Southern blot analysis of DNAs from 18 rodent-human somatic cell hybrids. Regional mapping by in situ hybridization localized the gene to 10q22-q24.Assignment of the vascular smooth muscle actin gene ACTSA to human chromosome. Smooth muscle alpha-actin gene requires two E-boxes for proper expression in vivo and is a target of class I basic helix-loop-helix proteins.