Anti-alpha-Smooth Muscle Actin antibody (monoclonal)

Product code: MA1106
Price: $200.00
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Product Details

Anti-alpha-Smooth Muscle Actin antibody (monoclonal)

Mouse IgG monoclonal antibody for alpha-Smooth Muscle Actin, actin, alpha 2, smooth muscle, aorta (ACTA2 ) detection. Tested with WB, IHC-P, IHC-F in Human;mouse;rat. No cross reactivity with other proteins.

Product Specifications

Immunogen N-terminal synthetic decapeptide of alpha-smooth muscle actin.
Pack Size 100μg/vial
Storage At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
Reactivity Human, Mouse, Rat
Cross Reactivity No cross reactivity with other proteins
Contents Mouse
Gene Name 1867
Protein Name Actin, aortic smooth muscle
Gene Full Name actin, alpha 2, smooth muscle, aorta
Synonyms AAT6|ACTSA|MYMY5|ACTSA|alpha-cardiac actin|cell growth-inhibiting gene 46 protein
Uniprot ID Human(P62736), Mouse(P62737), Rat(P62738)
Application IHC-P, IHC-F, WB
Form Lyophilized
Ig type Mouse IgG2a
Purification Ascites
Concentration 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.
Clone number 1A4
Host Mouse

Background

Ueyama et al.(1990) assigned the ACTSA gene to chromosome 10 by Southern blot analysis of DNAs from 18 rodent-human somatic cell hybrids. Regional mapping by in situ hybridization localized the gene to 10q22-q24.Assignment of the vascular smooth muscle actin gene ACTSA to human chromosome. Smooth muscle alpha-actin gene requires two E-boxes for proper expression in vivo and is a target of class I basic helix-loop-helix proteins.

Publications

Chlorogenicacid inhibits hypoxia-induced pulmonary artery smooth muscle cells proliferation via c-Src and Shc/Grb2/ERK2 signaling pathway
Protective effects of astaxanthin against ischemia/reperfusion induced renal injury in mice
Cryptotanshinone, an orally bioactive herbal compound from Danshen, attenuates atherosclerosis in apolipoprotein E-deficient mice: role of lectin-like oxidized LDL receptor-1 (LOX-1)
Rho-Associated Protein Kinases Play an Important Role in the Differentiation of Rat Adipose-Derived Stromal Cells into Cardiomyocytes In Vitro
Acute downregulation of miR-155 at wound sites leads to a reduced fibrosis through attenuating inflammatory response
Involvement of IL-13 and tissue transglutaminase in liver granuloma and fibrosis after schistosoma japonicum infection.
The green tea extract epigallocatechin-3-gallate inhibits irradiation-induced pulmonary fibrosis in adult rats
Expressionof the tissue inhibitor of metalloproteinase-3 by transplanted VSMCs modifies heart structure and function after myocardial infarction
Directed differentiation of aged human bone marrow multipotent stem cells effectively generates dopamine neurons
In vitro constitution of esophageal muscle tissue with endocyclic and exolongitudinal patterns
Mesenchymal stem-like cells isolated from human esophageal carcinoma and adjacent non-cancerous tissues
Lentiviral vector-mediated down-regulation of IL-17A receptor in hepatic stellate cells results in decreased secretion of IL-6
Suppression of lipopolysaccharide-induced upregulation of toll-like receptor 4 by emodin in mouse proximal tubular epithelial cells
VEGF induces proliferation of human hair follicle dermal papilla cells through VEGFR-2-mediated activation of ERK
Scutellarin inhibits translocation of protein kinase C in diabetic thoracic aorta of the rat
Injectable biodegradable hybrid hydrogels based on thiolated collagen and oligo(acryloyl carbonate)–poly(ethylene glycol)–oligo(acryloyl carbonate) copolymer for functional cardiac regeneration
Role of Wnt/β-catenin Signaling Pathway in the Mechanism of Calcification of Aortic Valve
Thymic Stromal Lymphopoietin Attenuates the Development of Atherosclerosis in ApoE−/− Mice
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