Anti-alpha-Smooth Muscle Actin antibody (monoclonal)

Product code: MA1106

Anti-alpha-Smooth Muscle Actin antibody (monoclonal)

Price: $200.00
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Product Details

Anti-alpha-Smooth Muscle Actin antibody (monoclonal)

Mouse IgG monoclonal antibody for alpha-Smooth Muscle Actin, actin, alpha 2, smooth muscle, aorta (ACTA2 ) detection. Tested with WB, IHC-P, IHC-F in Human;mouse;rat. No cross reactivity with other proteins.

Additional Information

Immunogen N-terminal synthetic decapeptide of alpha-smooth muscle actin.
Pack Size 100μg/vial
Storage At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
Reactivity Human, Mouse, Rat
Cross Reactivity No cross reactivity with other proteins.
Gene Name ACTA2
Protein Name Actin, aortic smooth muscle
Gene Full Name actin, alpha 2, smooth muscle, aorta
Synonyms AAT6|ACTSA|MYMY5|ACTSA|alpha-cardiac actin|cell growth-inhibiting gene 46 protein
Uniprot ID Human(P62736, Mouse)
Application IHC-P, IHC-F, WB
Form Lyophilized
Ig type Mouse IgG2a
Purification Ascites
Concentration 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.
Clone number 1A4
Host Mouse

Contents

Mouse

Background

Ueyama et al.(1990) assigned the ACTSA gene to chromosome 10 by Southern blot analysis of DNAs from 18 rodent-human somatic cell hybrids. Regional mapping by in situ hybridization localized the gene to 10q22-q24.Assignment of the vascular smooth muscle actin gene ACTSA to human chromosome. Smooth muscle alpha-actin gene requires two E-boxes for proper expression in vivo and is a target of class I basic helix-loop-helix proteins.

Boster Scientific References

The peripheral cannabinoid receptor 1 antagonist VD60 efficiently inhibits carbon tetrachloride-intoxicated hepatic fibrosis progression.
Expression and cellular distribution of TLR4, MyD88, and NF-_B in diabetic renal tubulointerstitial fibrosis, in vitro and in vivo.
Probucol attenuates ethanol-induced liver fibrosis in rats by inhibiting oxidative stress, extracellular matrix protein accumulation and cytokine production.
Vitamin K1 attenuates bile duct ligation-induced liver fibrosis in rats.
Function of the transforming growth factor-_1/c-Jun N-terminal kinase signaling pathway in the action of thalidomide on a rat model of pulmonary fibrosis.

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