Anti-5HT2A Receptor/HTR2A Antibody Picoband™

5-HT2A antibody

Boster Bio Anti-5HT2A Receptor/HTR2A Antibody Picoband™ catalog # PB9599. Tested in IHC, WB applications. This antibody reacts with Human, Rat.

Product Info Summary

SKU: PB9599
Size: 100 μg/vial
Reactive Species: Human, Rat
Host: Rabbit
Application: IHC, WB

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Product Name

Anti-5HT2A Receptor/HTR2A Antibody Picoband™

View all 5-HT2A Antibodies

SKU/Catalog Number

PB9599

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-5HT2A Receptor/HTR2A Antibody Picoband™ catalog # PB9599. Tested in IHC, WB applications. This antibody reacts with Human, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-5HT2A Receptor/HTR2A Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # PB9599)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human 5HT2A Receptor , different from the related mouse sequence by three amino acids, and from the related rat sequence by two amino acids.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PB9599 is reactive to HTR2A in Human, Rat

Applications

PB9599 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

53 kDa

Calculated molecular weight

52.603kDa

Background of 5-HT2A

The mammalian HTR2A (5-HT2A receptor) is a subtype of the 5-HT2 receptor that belongs to the serotonin receptor family and is a G protein-coupled receptor (GPCR). This is the main excitatory receptor subtype among the GPCRs for serotonin (5-HT), although 5-HT2A may also have an inhibitory effect on certain areas such as the visual cortex and the orbit frontal cortex. This receptor was given importance first as the target of psychedelic drugs like LSD. Later it came back to prominence because it was also found to be mediating, at least partly, the action of many antipsychotic drugs, especially the atypical ones. 5-HT2A also happens to be a necessary receptor for the spread of the human polyoma virus called JC virus. Sparkes et al. (1991) concluded that the gene is located on 13q14-q21 in man and on chromosome 14 in the mouse.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Rat, By Heat

Validation Images & Assay Conditions

Gene/Protein Information For HTR2A (Source: Uniprot.org, NCBI)

Gene Name

HTR2A

Full Name

5-hydroxytryptamine receptor 2A

Weight

52.603kDa

Superfamily

G-protein coupled receptor 1 family

Alternative Names

5-HT2 receptor; 5-HT-2; 5HT2A; 5-HT2A; 5-HT-2A; 5-hydroxytryptamine (serotonin) receptor 2A; 5-hydroxytryptamine receptor 2A; HTR2,5-HT2A; HTR2A; serotonin 5-HT-2A receptor; Serotonin receptor 2A HTR2A 5-HT2A, HTR2 5-hydroxytryptamine receptor 2A 5-hydroxytryptamine receptor 2A|5-HT2 receptor|5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled|serotonin 5-HT-2A receptor

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on HTR2A, check out the HTR2A Infographic

HTR2A infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for HTR2A: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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1 Customer Q&As for Anti-5HT2A Receptor/HTR2A Antibody Picoband™

Question

We are currently using anti-5HT2A Receptor/HTR2A antibody PB9599 for human tissue, and we are satisfied with the WB results. The species of reactivity given in the datasheet says human, rat. Is it likely that the antibody can work on monkey tissues as well?

Verified Customer

Verified customer

Asked: 2019-07-17

Answer

The anti-5HT2A Receptor/HTR2A antibody (PB9599) has not been tested for cross reactivity specifically with monkey tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in monkey you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2019-07-17

Order DetailsPrice
PB9599

100μg

$370
PB9599-10ug

10μg sample (liquid)

$99
PB9599-Biotin

100 μg Biotin conjugated

$570
PB9599-Cy3

100 μg Cy3 conjugated

$570
PB9599-Dylight488

100 μg Dylight488 conjugated

$570
PB9599-Dylight550

100 μg Dylight550 conjugated

$570
PB9599-Dylight594

100 μg Dylight594 conjugated

$570
PB9599-FITC

100 μg FITC conjugated

$570
PB9599-HRP

100 μg HRP conjugated

$570
PB9599-APC

100 μg APC conjugated

$670
PB9599-PE

100 μg PE conjugated

$670
PB9599-carrier-free

Carrier Free

$370

More conjugates/formats

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PB9599
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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