Anti-ARFGEF2 Antibody

ARFGEF2 antibody

Boster Bio Anti-ARFGEF2 Antibody (Catalog # A04212). Tested in WB, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: A04212
Size: 100 µl
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: IF, WB

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Product Name

Anti-ARFGEF2 Antibody

View all ARFGEF2 Antibodies

SKU/Catalog Number

A04212

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-ARFGEF2 Antibody (Catalog # A04212). Tested in WB, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-ARFGEF2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04212)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human ARFGEF2.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A04212 is reactive to ARFGEF2 in Human, Mouse, Rat

Applications

A04212 is guaranteed for IF, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

202.038kDa

Background of ARFGEF2

Promotes guanine-nucleotide exchange on ARF1 and ARF3 and to a lower extend on ARF5 and ARF6. Promotes the activation of ARF1/ARF5/ARF6 through replacement of GDP with GTP. Involved in the regulation of Golgi vesicular transport. Required for the integrity of the endosomal compartment. Involved in trafficking from the trans-Golgi network (TGN) to endosomes and is required for membrane association of the AP-1 complex and GGA1. Seems to be involved in recycling of the transferrin receptor from recycling endosomes to the plasma membrane. Probably is involved in the exit of GABA(A) receptors from the endoplasmic reticulum. Involved in constitutive release of tumor necrosis factor receptor 1 via exosome-like vesicles; the function seems to involve PKA and specifically PRKAR2B. Proposed to act as A kinase-anchoring protein (AKAP) and may mediate crosstalk between Arf and PKA pathways.

Togawa A., J. Biol. Chem. 274:12308-12315(1999).
Deloukas P., Nature 414:865-871(2001).
Beausoleil S.A., Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004)

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blotting: 1:500~1:3000

Immunofluorescence: 1:100~1:500

Validation Images & Assay Conditions

Gene/Protein Information For ARFGEF2 (Source: Uniprot.org, NCBI)

Gene Name

ARFGEF2

Full Name

Brefeldin A-inhibited guanine nucleotide-exchange protein 2

Weight

202.038kDa

Alternative Names

ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldinA-inhibited); ARFGEP2; BIG2brefeldin A-inhibited guanine nucleotide-exchange protein 2; Brefeldin A-inhibited GEP 2; dJ1164I10.1; FLJ23723; PVNH2 ARFGEF2 BIG2, PVNH2, dJ1164I10.1 ADP ribosylation factor guanine nucleotide exchange factor 2 brefeldin A-inhibited guanine nucleotide-exchange protein 2|ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)|brefeldin A-inhibited GEP 2

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on ARFGEF2, check out the ARFGEF2 Infographic

ARFGEF2 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for ARFGEF2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A04212-100uL

100uL

$360

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