Anti-ARID1A Antibody

ARID1A antibody

Boster Bio Anti-ARID1A Antibody (Catalog # A00247). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: A00247
Size: 0.1 mg
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: ELISA, IF, IHC-P, WB

Product Name

Anti-ARID1A Antibody

View all ARID1A Antibodies

SKU/Catalog Number

A00247

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-ARID1A Antibody (Catalog # A00247). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

ARID1A antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Cite This Product

Anti-ARID1A Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00247)

Host

Rabbit

Contents

ARID1A antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Clone Number

SK7

Isotype

IgG

Immunogen

ARID1A antibody was raised against an 18 amino acid peptide near the amino terminus of human ARID1A. The immunogen is located within amino acids 580 - 630 of ARID1A.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

ARID1A antibody is human, mouse and rat reactive. Multiple isoforms of ARID1A protein are known to exist.

Reactive Species

A00247 is reactive to ARID1A in Human, Mouse, Rat

Applications

A00247 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Observed Molecular Weight

68 kDa

Calculated molecular weight

242.045kDa

Background of ARID1A

The ARID1A protein is a member of the SWI/SNF family, whose members are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. ARID1A is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin (1). It possesses a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. The C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that ARID1A confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions (2).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

ARID1A antibody can be used for detection of ARID1A by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

Gene/Protein Information For ARID1A (Source: Uniprot.org, NCBI)

Gene Name

ARID1A

Full Name

AT-rich interactive domain-containing protein 1A

Weight

242.045kDa

Alternative Names

ARID domain-containing protein 1A; AT rich interactive domain 1A (SWI- like); AT rich interactive domain 1A (SWI-like); AT-rich interactive domain-containing protein 1A; B120SWI-like protein; BAF250a; BAF250SWI/SNF complex protein p270; BM029; brain protein 120; BRG1-associated factor 250; BRG1-associated factor 250a; C10rf4; C1orf4SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatinsubfamily F member 1; chromatin remodeling factor p250; hELD; hOSA1; matrix associated, actin dependent regulator of chromatin; Osa homolog 1; OSA1 nuclear protein; OSA1; P270; SMARCF1; subfam ARID1A B120, BAF250, BAF250a, BM029, C1orf4, CSS2, ELD, MRD14, OSA1, P270, SMARCF1, hELD, hOSA1 AT-rich interaction domain 1A AT-rich interactive domain-containing protein 1A|ARID domain-containing protein 1A|AT rich interactive domain 1A (SWI-like)|BRG1-associated factor 250a|OSA1 nuclear protein|SWI-like protein|SWI/SNF complex protein p270|SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1|brain protein 120|chromatin remodeling factor p250|osa homolog 1

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on ARID1A, check out the ARID1A Infographic

ARID1A infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for ARID1A: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A00247-0.1 mg

0.1 mg

$449

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