Anti-C-C motif chemokine 8 CCL8 Antibody

CCL8/MCP-2 antibody

Boster Bio Anti-C-C motif chemokine 8 CCL8 Antibody catalog # A03237. Tested in WB,IHC,IF applications. This antibody reacts with Human,Mouse.

Product Info Summary

SKU: A03237
Size: 100ul
Reactive Species: Human, Mouse
Host: Rabbit
Application: IF, IHC, WB

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Product Name

Anti-C-C motif chemokine 8 CCL8 Antibody

View all CCL8/MCP-2 Antibodies

SKU/Catalog Number

A03237

Size

100ul

Form

Liquid

Description

Boster Bio Anti-C-C motif chemokine 8 CCL8 Antibody catalog # A03237. Tested in WB,IHC,IF applications. This antibody reacts with Human,Mouse.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-C-C motif chemokine 8 CCL8 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03237)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human ZNF147.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A03237 is reactive to CCL8 in Human, Mouse

Applications

A03237 is guaranteed for IF, IHC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

11.246kDa

Background of CCL8/MCP-2

Functions as a ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection. Promotes ISGylation of 14-3-3 sigma (SFN), an adapter protein implicated in the regulation of a large spectrum signaling pathway. Mediates estrogen action in various target organs.

Inoue S., Proc. Natl. Acad. Sci. U.S.A. 90:11117-11121(1993).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Rush J., Nat. Biotechnol. 23:94-101(2005).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:2000
IHC: 1:50-1:100
IF: 1:50-1:100

Validation Images & Assay Conditions

Gene/Protein Information For CCL8 (Source: Uniprot.org, NCBI)

Gene Name

CCL8

Full Name

C-C motif chemokine 8

Weight

11.246kDa

Superfamily

intercrine beta (chemokine CC) family

Alternative Names

C-C motif chemokine 8; CCL8; chemokine (C-C motif) ligand 8; HC14; MCP2; MCP-2; member 8 (monocyte chemotactic protein 2); monocyte chemoattractant protein 2; SCYA10; small-inducible cytokine A8 CCL8 HC14, MCP-2, MCP2, SCYA10, SCYA8 C-C motif chemokine ligand 8 C-C motif chemokine 8|chemokine (C-C motif) ligand 8|monocyte chemoattractant protein 2|monocyte chemotactic protein 2|small inducible cytokine subfamily A (Cys-Cys), member 8 (monocyte chemotactic protein 2)|small-inducible cytokine A8

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on CCL8, check out the CCL8 Infographic

CCL8 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for CCL8: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A03237-100ul

100ul

$405

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