Anti-C Reactive Protein/CRP Antibody

C-Reactive Protein/CRP antibody

Boster Bio Anti-C Reactive Protein/CRP Antibody catalog # PA1028. Tested in WB applications. This antibody reacts with Human. Cited in 1 publication(s).

Product Info Summary

SKU: PA1028
Size: 100 μg/vial
Reactive Species: Human
Host: Rabbit
Application: WB

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Product Name

Anti-C Reactive Protein/CRP Antibody

View all C-Reactive Protein/CRP Antibodies

SKU/Catalog Number

PA1028

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-C Reactive Protein/CRP Antibody catalog # PA1028. Tested in WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-C Reactive Protein/CRP Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1028)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human C Reactive Protein.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA1028 is reactive to CRP in Human

Applications

PA1028 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

43 kDa

Calculated molecular weight

25.039kDa

Background of C-Reactive Protein/CRP

C Reactive Protein (CRP) is a major acute phase reactant synthesized primarily in the liver hepatocytes. It is composed of 5 identical, 21,500-molecular weight subunits. CRP mediates activities associated with preimmune nonspecific host resistance. CRP shows the strongest association with cardiovascular events. It is detectable on the surface of about 4% of normal peripheral blood lymphocytes. Acute phase reactant CRP is produced in the liver.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human

Validation Images & Assay Conditions

Gene/Protein Information For CRP (Source: Uniprot.org, NCBI)

Gene Name

CRP

Full Name

C-reactive protein

Weight

25.039kDa

Superfamily

pentraxin family

Alternative Names

C-Reactive Protein; C-reactive protein, pentraxin-related; CRP; MGC88244; pentraxin 1; PTX1MGC149895 CRP PTX1 C-reactive protein C-reactive protein|C-reactive protein, pentraxin-related|pentraxin 1

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on CRP, check out the CRP Infographic

CRP infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for CRP: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

PA1028 has been cited in 1 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Shi L, Song J, Zhang X, Li Y, Li H. Exp Ther Med. 2013 Aug;6(2):532-536. Epub 2013 May 28. Correlation Between The Microinflammatory State And Left Ventricular Structural And Functional Changes In Maintenance Haemodialysis Patients.

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4 Customer Q&As for Anti-C Reactive Protein/CRP Antibody

Question

My question regards using your anti-C Reactive Protein/CRP antibody for innate immune response studies. Has this antibody been tested with western blotting on smmc cell lysate? We would like to see some validation images before ordering.

Verified Customer

Verified customer

Asked: 2020-04-23

Answer

I appreciate your inquiry. This PA1028 anti-C Reactive Protein/CRP antibody is tested on smmc cell lysate, ht1080 cell lysate. It is guaranteed to work for WB in human. Our Boster guarantee will cover your intended experiment even if the sample type has not been be directly tested.

Boster Scientific Support

Answered: 2020-04-23

Question

My team were content with the WB result of your anti-C Reactive Protein/CRP antibody. However we have seen positive staining in right lobe of liver secreted. using this antibody. Is that expected? Could you tell me where is CRP supposed to be expressed?

J. Krishna

Verified customer

Asked: 2020-01-06

Answer

According to literature, right lobe of liver does express CRP. Generally CRP expresses in secreted. Regarding which tissues have CRP expression, here are a few articles citing expression in various tissues:
Liver, Pubmed ID: 15489334
Urinary bladder, Pubmed ID: 14702039

Boster Scientific Support

Answered: 2020-01-06

Question

We have observed staining in human urinary bladder. Any tips? Is anti-C Reactive Protein/CRP antibody supposed to stain urinary bladder positively?

P. Banerjee

Verified customer

Asked: 2019-11-12

Answer

Based on literature urinary bladder does express CRP. Based on Uniprot.org, CRP is expressed in right lobe of liver, liver, urinary bladder, among other tissues. Regarding which tissues have CRP expression, here are a few articles citing expression in various tissues:
Liver, Pubmed ID: 15489334
Urinary bladder, Pubmed ID: 14702039

Boster Scientific Support

Answered: 2019-11-12

Question

We are currently using anti-C Reactive Protein/CRP antibody PA1028 for human tissue, and we are well pleased with the WB results. The species of reactivity given in the datasheet says human. Is it true that the antibody can work on pig tissues as well?

Verified Customer

Verified customer

Asked: 2017-08-21

Answer

The anti-C Reactive Protein/CRP antibody (PA1028) has not been tested for cross reactivity specifically with pig tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in pig you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2017-08-21

Order DetailsPrice
PA1028

100μg

$370
PA1028-10ug

10μg sample (liquid)

$99
PA1028-Biotin

100 μg Biotin conjugated

$570
PA1028-Cy3

100 μg Cy3 conjugated

$570
PA1028-Dylight488

100 μg Dylight488 conjugated

$570
PA1028-Dylight550

100 μg Dylight550 conjugated

$570
PA1028-Dylight594

100 μg Dylight594 conjugated

$570
PA1028-FITC

100 μg FITC conjugated

$570
PA1028-HRP

100 μg HRP conjugated

$570
PA1028-APC

100 μg APC conjugated

$670
PA1028-PE

100 μg PE conjugated

$670
PA1028-carrier-free

Carrier Free

$370

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