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SKU:MA1008
Clonality:Monoclonal
Clone Number:CN-A1
Application:IHC-P, WB
Price: $200.00
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Overview

Product Name Anti-Calcineurin Alpha Antibody (Monoclonal, CN-A1)
SKU/Catalog Number MA1008
Description Mouse IgG monoclonal antibody for Calcineurin alpha, protein phosphatase 3, regulatory subunit B, alpha (PPP3R1) detection. Tested with WB, IHC-P in Human;bovine;rat. No cross reactivity with other proteins.
Cite This Product Anti-Calcineurin Alpha Antibody (Monoclonal, CN-A1) CN-A1 (Boster Biological Technology, Pleasanton CA, USA, Catalog # MA1008)
Replacement Item This antibody may replace the following items: sc-130393|sc-135349|sc-169808|sc-169810|sc-33166|sc-373803|sc-376734|sc-393131|sc-6119 from Santa Cruz Biotechnology.
Host Mouse
Isotype Mouse IgG1
Validated Species Bovine, Human, Rat
Predicted Species Bovine, Canine, Chicken, Monkey

*This antibody is predicted to react with the above species based on antigen sequence similarities. Our Boster Guarantee covers the use of this product with the above species.

Application IHC-P, WB

*Our Boster Guarantee covers the use of this product in the above tested applications.

**For positive and negative control design, consult "Tissue specificity" under Protein Target Info.

Recommended Detection Systems Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P).
*Blocking peptide can be purchased at $50. Contact us for more information
**Boster also offers various secondary antibodies for Immunoflourescecne and IHC. Take advantage of the buy 1 primary antibody get 1 secondary antibody for free promotion for the entire year 2017!
Immunogen Bovine brain calcineurin.
Cross Reactivity No cross reactivity with other proteins
Pack Size 100μg/vial

Properties

Clonality Monoclonal
Clone Number CN-A1
Form Liquid
Contents Each vial contains 50% glycerol, 1.2% Sodium acetate, 1% BSA, 0.02% NaN3.
*carrier free antibody available upon request.
Storage At -20˚C for one year, at 4˚C for one month. Avoid repeated freezing and thawing.
Purification Ascites
Isotype Mouse IgG1

Protein Target Info (Source: Uniprot.org)

You can check the tissue specificity below for information on selecting positive and negative control.

Gene Name Ppp3r1
Protein Name Calcineurin subunit B type 1
Molecular Weight 19300 MW
Protein Function Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.
Tissue Specificity Isoform 2 is testis specific. .
Sequence Similarities Belongs to the calcineurin regulatory subunit family.
Subcellular Localization Cytoplasm, cytosol . Cell membrane ; Lipid-anchor . Cell membrane, sarcolemma. Translocates from the cytosol to the sarcolemma in a CIB1- dependent manner during cardiomyocytes hypertrophy. .
Uniprot ID P63100
Alternative Names Calcineurin subunit B type 1;Protein phosphatase 2B regulatory subunit 1;Protein phosphatase 3 regulatory subunit B alpha isoform 1;Ppp3r1;Cna2, Cnb;
Research Areas PPP3R1|
*if product is indicated to react with multiple species, protein info is based on the human gene.

Background for Calcineurin subunit B type 1

Calcineurin, the Ca(2+)/calmodulin-regulated protein phosphatase, first detected in skeletal muscle and brain, has been found in all cells from yeast to mammals. Calcineurin A alpha(PPP3CA),is located on human chromosomes 4, Chromosomal mapping of the human genes for the calmodulin-dependent protein phosphatase(calcineurin) catalytic subunit. Calcineurin regulates bone formation by the osteoblast.
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FAQs

Q: Is your western blot protocol provided from the website applicable for all your antibodies? Keyword: applications, WB
A: The protocol is applicable for all our antibodies in WB, the NC Membrane(0.45μm or 0.22μm) and transfer time(70 mins or 50 mins) depends on the protein molecular weight, details can be found in included protocol.
Q: Can I conjugate markers to this antibody? Can I link custom conjugates to this antibody? Keyword: conjugation
A: The antibody is stored with BSA and cannot be conjugated with markers. Carrier free antibodies are available upon request. Please contact support@bosterbio.com
Q: Can you provide monoclonal antibodies carrier free?
A: We cannot.
Q: What are some alternative names that could be used to describe this product?
A: One other very common name is ccn1 antibody