Anti-Carbonyl Reductase 3 CBR3 Antibody

CBR3 antibody

Boster Bio Anti-Carbonyl Reductase 3 CBR3 Antibody catalog # A06200-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: A06200-1
Size: 100μl
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: WB

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Product Name

Anti-Carbonyl Reductase 3 CBR3 Antibody

View all CBR3 Antibodies

SKU/Catalog Number

A06200-1

Size

100μl

Form

Liquid

Description

Boster Bio Anti-Carbonyl Reductase 3 CBR3 Antibody catalog # A06200-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Carbonyl Reductase 3 CBR3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06200-1)

Host

Rabbit

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from the Internal region of human Carbonyl Reductase 3. at AA rangle: 120-200

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A06200-1 is reactive to CBR3 in Human, Mouse, Rat

Applications

A06200-1 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

39 kDa

Calculated molecular weight

30.85kDa

Background of CBR3

APC2, also known as Anaphase promoting complex subunit 2, APC2, Cyclosome subunit 2, and ANAPC2, is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/cyclosome protein complex promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitors, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains at least eleven subunits. The composition of APC is highly conserved in organisms from yeast to humans. APC2 is a cullin family member that interacts through the cullin domain with ANAPC11 and UBCH10.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB, 1:500-1:2000

Validation Images & Assay Conditions

Gene/Protein Information For CBR3 (Source: Uniprot.org, NCBI)

Gene Name

CBR3

Full Name

Carbonyl reductase [NADPH] 3

Weight

30.85kDa

Superfamily

short-chain dehydrogenases/reductases (SDR) family

Alternative Names

carbonyl reductase (NADPH) 3; carbonyl reductase (NADPH) 3, EC 1.1.1.18410EC 1.1.1; carbonyl reductase [NADPH] 3; carbonyl reductase 3; EC 1.1.1.184; hCBR3; NADPH-dependent carbonyl reductase 3; SDR21C2; short chain dehydrogenase/reductase family 21C, member 2 CBR3 HEL-S-25, SDR21C2, hCBR3 carbonyl reductase 3 carbonyl reductase [NADPH] 3|NADPH-dependent carbonyl reductase 3|carbonyl reductase (NADPH) 3|epididymis secretory protein Li 25|short chain dehydrogenase/reductase family 21C member 2

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on CBR3, check out the CBR3 Infographic

CBR3 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for CBR3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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4 Customer Q&As for Anti-Carbonyl Reductase 3 CBR3 Antibody

Question

I was wanting to use your anti-Carbonyl Reductase 3 antibody for WB for human placenta on frozen tissues, but I want to know if it has been tested for this particular application. Has this antibody been tested and is this antibody a good choice for human placenta identification?

Verified Customer

Verified customer

Asked: 2020-03-18

Answer

As indicated on the product datasheet, A06200-1 anti-Carbonyl Reductase 3 antibody has been tested for WB on human, mouse, rat tissues. We have an innovator award program that if you test this antibody and show it works in human placenta in IHC-frozen, you can get your next antibody for free.

Boster Scientific Support

Answered: 2020-03-18

Question

Would anti-Carbonyl Reductase 3 antibody A06200-1 work for WB with placenta?

Verified Customer

Verified customer

Asked: 2019-11-28

Answer

According to the expression profile of placenta, CBR3 is highly expressed in placenta. So, it is likely that anti-Carbonyl Reductase 3 antibody A06200-1 will work for WB with placenta.

Boster Scientific Support

Answered: 2019-11-28

Question

Is this A06200-1 anti-Carbonyl Reductase 3 antibody reactive to the isotypes of CBR3?

Verified Customer

Verified customer

Asked: 2017-10-23

Answer

The immunogen of A06200-1 anti-Carbonyl Reductase 3 antibody is Synthesized peptide derived from the Internal region of human Carbonyl Reductase 3. at AA rangle: 120-200. Could you tell me which isotype you are interested in so I can help see if the immunogen is part of this isotype?

Boster Scientific Support

Answered: 2017-10-23

Question

We are currently using anti-Carbonyl Reductase 3 antibody A06200-1 for human tissue, and we are happy with the WB results. The species of reactivity given in the datasheet says human, mouse, rat. Is it true that the antibody can work on monkey tissues as well?

J. Moore

Verified customer

Asked: 2014-01-14

Answer

The anti-Carbonyl Reductase 3 antibody (A06200-1) has not been validated for cross reactivity specifically with monkey tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in monkey you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2014-01-14

Order DetailsPrice
A06200-1

100uL

$399

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