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SKU:MA1013
Clonality:Monoclonal
Clone Number:CTD-19
Application:IHC-P, WB
Price: $200.00
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Overview

Product Name Anti-Cathepsin D Antibody
Description Mouse IgG monoclonal antibody for Cathepsin D, cathepsin D (CTSD) detection. Tested with WB, IHC-P in Human. No cross reactivity with other proteins.
Cite This Product Anti-Cathepsin D Antibody CTD-19 (Boster Biological Technology, Pleasanton CA, USA, Catalog # MA1013)
Replacement Item This antibody may replace the following items: sc-161659|sc-161658|sc-161658|sc-161659 from Santa Cruz Biotechnology.
Host Mouse
Isotype Mouse IgG2a
Validated Species Human
Application IHC-P, WB

*Our Boster Guarantee covers the use of this product in the above tested applications.

**For positive and negative control design, consult "Tissue specificity" under Protein Target Info.

Recommended Detection Systems Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P).
*Blocking peptide can be purchased at $50. Contact us for more information
**Boster also offers various secondary antibodies for Immunoflourescecne and IHC. Take advantage of the buy 1 primary antibody get 1 secondary antibody for free promotion for the entire year 2017!
Immunogen Human liver cathepsin D.
Cross Reactivity No cross reactivity with other proteins
Pack Size 100μg/vial

Properties

Clonality Monoclonal
Clone Number CTD-19
Form Lyophilized
Contents Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
*carrier free antibody available upon request.
Concentration Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Storage At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
Purification Ascites
Isotype Mouse IgG2a

Protein Target Info (Source: Uniprot.org)

You can check the tissue specificity below for information on selecting positive and negative control.

Gene Name Ctsd
Protein Name Cathepsin D
Molecular Weight 44681 MW
Protein Function Acid protease active in intracellular protein breakdown.
Tissue Specificity CTSD: Expressed in the aorta extrcellular space (atprotein level).
Sequence Similarities Belongs to the peptidase A1 family.
Subcellular Localization Lysosome. Melanosome . Secreted, extracellular space .
Uniprot ID P24268
Alternative Names Cathepsin D;3.4.23.5;Cathepsin D 12 kDa light chain;Cathepsin D 9 kDa light chain;Cathepsin D 34 kDa heavy chain;Cathepsin D 30 kDa heavy chain;Ctsd;
Research Areas |neuroscience|cell adhesion proteins|membrane proteins| signal transduction|cytoskeleton / ecm|extracellular matrix|ecm enzymes|other enzymes| cancer|invasion/microenvironment| cell biology|proteolysis / ubiquitin|proteolytic enzymes|cysteine protease|cathepsins|
*if product is indicated to react with multiple species, protein info is based on the human gene.

Background for Cathepsin D

Cathepsin D is one of the lysosomal proteinases. It is ubiquitously expressed and is involved in proteolytic degradation, cell invasion, and apoptosis. Cathepsin D is mapped to chromosome 11. The amino acid sequence predicted from the cDNA sequence shows that human cathepsin D consists of 412 amino acids with 20 and 44 amino acids in a pre- and a prosegment, respectively.

Anti-Cathepsin D Antibody Images

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Anti-Cathepsin D Antibody
Anti- Cathepsin D antibody, MA1013, IHC(P)
IHC(P): Human Intestinal Cancer Tissue
Anti-Cathepsin D Antibody
Anti- Cathepsin D antibody, MA1013, IHC(P)
IHC(P): Human Lung Cancer Tissue
Anti-Cathepsin D Antibody
Anti- Cathepsin D antibody, MA1013, IHC(P)
IHC(P): Human Mammary Cancer Tissue
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FAQs

Q: Is your western blot protocol provided from the website applicable for all your antibodies? Keyword: applications, WB
A: The protocol is applicable for all our antibodies in WB, the NC Membrane(0.45μm or 0.22μm) and transfer time(70 mins or 50 mins) depends on the protein molecular weight, details can be found in included protocol.
Q: Can I conjugate markers to this antibody? Can I link custom conjugates to this antibody? Keyword: conjugation
A: The antibody is stored with BSA and cannot be conjugated with markers. Carrier free antibodies are available upon request. Please contact support@bosterbio.com
Q: Can you provide monoclonal antibodies carrier free?
A: We cannot.
Q: What are some alternative names that could be used to describe this product?
A: One other very common name is cd antibody