Anti-CD11a / Integrin alphaL / LFA-1 alpha Chain Monoclonal Antibody

ITGAL antibody

Boster Bio Anti-CD11a / Integrin alphaL / LFA-1 alpha Chain Monoclonal Antibody (Catalog # M04466). Tested in Flow Cytometry, IF, Functional Assay applications. This antibody reacts with Human.

Product Info Summary

SKU: M04466
Size: 100ug/vial
Reactive Species: Human
Host: Mouse
Application: Flow Cytometry, IF, Functional Assay

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Product Name

Anti-CD11a / Integrin alphaL / LFA-1 alpha Chain Monoclonal Antibody

View all ITGAL Antibodies

SKU/Catalog Number

M04466

Size

100ug/vial

Form

Liquid

Description

Boster Bio Anti-CD11a / Integrin alphaL / LFA-1 alpha Chain Monoclonal Antibody (Catalog # M04466). Tested in Flow Cytometry, IF, Functional Assay applications. This antibody reacts with Human.

Storage & Handling

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Cite This Product

Anti-CD11a / Integrin alphaL / LFA-1 alpha Chain Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M04466)

Host

Mouse

Contents

Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Clonality

Monoclonal

Clone Number

Clone: CRIS-3

Isotype

IgG2b, kappa

Immunogen

Stimulated human leukocytes

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

Does not cross-react with primate, avian or amphibian GR.

Reactive Species

M04466 is reactive to ITGAL in Human

Applications

M04466 is guaranteed for Flow Cytometry, IF, Functional Assay Boster Guarantee

Observed Molecular Weight

68 kDa

Calculated molecular weight

128.77kDa

Background of ITGAL

Recognizes a protein of 180kDa, identified as CD11a (Leucocyte Workshop II; Code N202). CD11a complex with the 2 subunit of the integrin family, CD18, to form the cell surface heterodimer, LFA-1 or CD11a /C18 (aLbL). LFA-1 is expressed on all leukocytes including lymphocytes, monocytes, and granulocytes. It is involved in leukocyte adhesion to its ligands including intercellular adhesion molecule-1 (ICAM-1 or CD54), ICAM-2 (CD102), ICAM-3 (CD50) and Telencephalin (TLN) and play a role in most immune/inflammatory responses.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Reconstitute with distilled water.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Flow Cytometry (1-2ug/million cells)
Immunofluorescence (1-2ug/ml) Functional Studies (Order Ab without BSA & Azide)
Optimal dilution for a specific application should be determined.

Validation Images & Assay Conditions

Gene/Protein Information For ITGAL (Source: Uniprot.org, NCBI)

Gene Name

ITGAL

Full Name

Integrin alpha-L

Weight

128.77kDa

Superfamily

integrin alpha chain family

Alternative Names

CD11 antigen-like family member A; CD11a antigen; CD11a; CD11Aantigen CD11A (p180), lymphocyte function-associated antigen 1, alphapolypeptide; Integrin alpha L; integrin alpha-L; integrin gene promoter; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen1; alpha polypeptide); ITGAL; Leukocyte adhesion glycoprotein LFA-1 alpha chain; Leukocyte function-associated molecule 1 alpha chain; LFA-1 alpha; LFA-1; LFA1A; LFA-1A; Ly-15; Ly-21; lymphocyte function-associated antigen 1 ITGAL CD11A, LFA-1, LFA1A integrin subunit alpha L integrin alpha-L|CD11 antigen-like family member A|LFA-1 alpha|LFA-1A|antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide|integrin gene promoter|integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)|leukocyte adhesion glycoprotein LFA-1 alpha chain|leukocyte function-associated molecule 1 alpha chain|lymphocyte function-associated antigen 1, alpha polypeptide

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on ITGAL, check out the ITGAL Infographic

ITGAL infographic

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In this infographic, you will see the following information for ITGAL: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
M04466-100ug

100 μg

$468

Free Secondary Antibody

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M04466
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$468.00

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