Product Info Summary
SKU: | M04466 |
---|---|
Size: | 100ug/vial |
Reactive Species: | Human |
Host: | Mouse |
Application: | Flow Cytometry, IF, Functional Assay |
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Product info
Product Name
Anti-CD11a / Integrin alphaL / LFA-1 alpha Chain Monoclonal Antibody
SKU/Catalog Number
M04466
Size
100ug/vial
Form
Liquid
Description
Boster Bio Anti-CD11a / Integrin alphaL / LFA-1 alpha Chain Monoclonal Antibody (Catalog # M04466). Tested in Flow Cytometry, IF, Functional Assay applications. This antibody reacts with Human.
Storage & Handling
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Cite This Product
Anti-CD11a / Integrin alphaL / LFA-1 alpha Chain Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M04466)
Host
Mouse
Contents
Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Clonality
Monoclonal
Clone Number
Clone: CRIS-3
Isotype
IgG2b, kappa
Immunogen
Stimulated human leukocytes
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Does not cross-react with primate, avian or amphibian GR.
Reactive Species
M04466 is reactive to ITGAL in Human
Applications
M04466 is guaranteed for Flow Cytometry, IF, Functional Assay Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
128.77kDa
Background of ITGAL
Recognizes a protein of 180kDa, identified as CD11a (Leucocyte Workshop II; Code N202). CD11a complex with the 2 subunit of the integrin family, CD18, to form the cell surface heterodimer, LFA-1 or CD11a /C18 (aLbL). LFA-1 is expressed on all leukocytes including lymphocytes, monocytes, and granulocytes. It is involved in leukocyte adhesion to its ligands including intercellular adhesion molecule-1 (ICAM-1 or CD54), ICAM-2 (CD102), ICAM-3 (CD50) and Telencephalin (TLN) and play a role in most immune/inflammatory responses.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Reconsitution
Reconstitute with distilled water.
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Flow Cytometry (1-2ug/million cells)
Immunofluorescence (1-2ug/ml) Functional Studies (Order Ab without BSA & Azide)
Optimal dilution for a specific application should be determined.
Validation Images & Assay Conditions
Click image to see more details
Flow Cytometric staining of human PBMCs using Anti-CD11a Mouse Monoclonal Antibody (CRIS-3).
Protein Target Info & Infographic
Gene/Protein Information For ITGAL (Source: Uniprot.org, NCBI)
Gene Name
ITGAL
Full Name
Integrin alpha-L
Weight
128.77kDa
Superfamily
integrin alpha chain family
Alternative Names
CD11 antigen-like family member A; CD11a antigen; CD11a; CD11Aantigen CD11A (p180), lymphocyte function-associated antigen 1, alphapolypeptide; Integrin alpha L; integrin alpha-L; integrin gene promoter; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen1; alpha polypeptide); ITGAL; Leukocyte adhesion glycoprotein LFA-1 alpha chain; Leukocyte function-associated molecule 1 alpha chain; LFA-1 alpha; LFA-1; LFA1A; LFA-1A; Ly-15; Ly-21; lymphocyte function-associated antigen 1 ITGAL CD11A, LFA-1, LFA1A integrin subunit alpha L integrin alpha-L|CD11 antigen-like family member A|LFA-1 alpha|LFA-1A|antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide|integrin gene promoter|integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)|leukocyte adhesion glycoprotein LFA-1 alpha chain|leukocyte function-associated molecule 1 alpha chain|lymphocyte function-associated antigen 1, alpha polypeptide
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ITGAL, check out the ITGAL Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ITGAL: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-CD11a / Integrin alphaL / LFA-1 alpha Chain Monoclonal Antibody (M04466)
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No publications found for M04466
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