Anti-CD74 Antibody Picoband™

CD74 antibody

Boster Bio Anti-CD74 Antibody Picoband™ catalog # A01340-3. Tested in IHC, WB applications. This antibody reacts with Human.

Product Info Summary

SKU: A01340-3
Size: 100 μg/vial
Reactive Species: Human
Host: Rabbit
Application: IHC, WB

Product Name

Anti-CD74 Antibody Picoband™

View all CD74 Antibodies

SKU/Catalog Number

A01340-3

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-CD74 Antibody Picoband™ catalog # A01340-3. Tested in IHC, WB applications. This antibody reacts with Human.

Storage & Handling

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Cite This Product

Anti-CD74 Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01340-3)

Host

Rabbit

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Clonality

Polyclonal

Immunogen

A synthetic peptide corresponding to a sequence of human CD74 (EDHVMHLLQNADPLKVYPPLK).

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A01340-3 is reactive to CD74 in Human

Applications

A01340-3 is guaranteed for IHC, WB Boster Guarantee

Background of CD74

HLA class II histocompatibility antigen gamma chain also known as HLA-DR antigens-associated invariant chain or CD74 (Cluster of Differentiation 74), is a protein that in humans is encoded by the CD74 gene. The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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Reconsitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

Western blot, 0.25-0.5 μg/ml, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human

Validation Images & Assay Conditions

Gene/Protein Information For CD74 (Source: Uniprot.Org, NCBI)

Uniprot ID

P04233

Gene ID

972

Gene Name

CD74

Full Name

HLA class II histocompatibility antigen gamma chain

Weight

33.516kDa

Alternative Names

CD74 antigen (invariant polypeptide of major histocompatibility complex, classII antigen-associated); CD74 antigen; CD74 molecule, major histocompatibility complex, class II invariant chain; CD74; CLIP; DHLAG; DHLAGgamma chain of class II antigens; HLA class II histocompatibility antigen gamma chain; HLADG; HLA-DR antigens-associated invariant chain; HLA-DR-gamma; Ia antigen-associated invariant chain; Ia-associated invariant chain; Ia-gamma; Ii; INVG34; MHC HLA-DR gamma chain; p33 CD74 DHLAG, HLADG, II, Ia-GAMMA, p33 CD74 molecule HLA class II histocompatibility antigen gamma chain|CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)|CD74 molecule, major histocompatibility complex, class II invariant chain|HLA-DR antigens-associated invariant chain|HLA-DR-gamma|Ia-associated invariant chain|MHC HLA-DR gamma chain|gamma chain of class II antigens

*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".

For more info on CD74, check out the CD74 Infographic

CD74 infographic

We have 30,000+ of these available, one for each gene! check them out.

In this infographic you will see the following information for CD74: database IDs, super-family, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us [email protected]

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Size

Conjugation

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Total: $315

Size:100 μg

SKU:A01340-3

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A01340-3
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$315.00

$50 fee for conjugation. Antibody size is reduced to 50ug.

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