Anti-CKIP1 PLEKHO1 Antibody

CKIP-1 antibody

Boster Bio Anti-CKIP1 PLEKHO1 Antibody (Catalog # A06065). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: A06065
Size: 0.1 mg
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: ELISA, WB

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Product Name

Anti-CKIP1 PLEKHO1 Antibody

View all CKIP-1 Antibodies

SKU/Catalog Number

A06065

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-CKIP1 PLEKHO1 Antibody (Catalog # A06065). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

CKIP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-CKIP1 PLEKHO1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06065)

Host

Rabbit

Contents

CKIP1 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Clone Number

SK7

Isotype

IgG

Immunogen

CKIP1 antibody was raised against an 18 amino acid synthetic peptide from near the carboxy terminus of human CKIP1. The immunogen is located within the last 50 amino acids of CKIP1.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

ATAD3A antibody is predicted to not cross-react with other ATAD protein family members. At least two isoforms are known to exist.

Reactive Species

A06065 is reactive to PLEKHO1 in Human, Mouse, Rat

Applications

A06065 is guaranteed for ELISA, WB Boster Guarantee

Observed Molecular Weight

68 kDa

Calculated molecular weight

46.237kDa

Background of CKIP-1

CKIP1 was identified through a yeast-two hybrid screening as a protein that would interact with only one of the two catalytic subunits of the casein kinase 2 complex. CKIP1 is a pleckstrin homology domain-containing protein localized within the nucleus and at the plasma membrane that interacts with CK2alpha but not CK2alpha', and is thought to play a role in targeting CK2alpha to a particular cellular location. CKIP1 has been implicated in muscle differentiation and the regulation of cell morphology and actin cytoskeleton. CKIP1 can also interact with other proteins such as ATM, an upstream kinase of p53, and recruit the nuclear ATM to the plasma membrane, suggesting CKIP1 may regulate ATM function through re-localizing ATM. CKIP1 can also form a complex with the kinase AKT, leading to a down-regulation of PI3K/AKT signaling and suppression of tumor growth in vivo.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

CKIP1 antibody can be used for detection of CKIP1 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

Gene/Protein Information For PLEKHO1 (Source: Uniprot.org, NCBI)

Gene Name

PLEKHO1

Full Name

Pleckstrin homology domain-containing family O member 1

Weight

46.237kDa

Alternative Names

2810052M02Rik; Casein kinase 2-interacting protein 1; C-Jun-binding protein; CK2 interacting protein 1; HQ0024c protein; CK2-interacting protein 1; CKIP1; CKIP-1PH domain-containing family O member 1; JBP; OC120; Osteoclast maturation-associated gene 120 protein; pleckstrin homology domain containing, family O member 1; pleckstrin homology domain-containing family O member 1 PLEKHO1 CKIP-1, CKIP1, JBP, OC120 pleckstrin homology domain containing O1 pleckstrin homology domain-containing family O member 1|C-Jun-binding protein|CK2 interacting protein 1; HQ0024c protein|CK2-interacting protein 1|PH domain-containing family O member 1|casein kinase 2-interacting protein 1|osteoclast maturation-associated gene 120 protein

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on PLEKHO1, check out the PLEKHO1 Infographic

PLEKHO1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for PLEKHO1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A06065-0.1 mg

0.1 mg

$449

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