Anti-Coxsackie Adenovirus Receptor/CXADR Antibody

CXADR antibody

Boster Bio Anti-Coxsackie Adenovirus Receptor/CXADR Antibody catalog # PA1852. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: PA1852
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: WB

Product Name

Anti-Coxsackie Adenovirus Receptor/CXADR Antibody

View all CXADR Antibodies

SKU/Catalog Number

PA1852

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Coxsackie Adenovirus Receptor/CXADR Antibody catalog # PA1852. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Coxsackie Adenovirus Receptor/CXADR Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1852)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human Coxsackie Adenovirus Receptor, identical to the related rat and mouse sequences.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA1852 is reactive to CXADR in Human, Mouse, Rat

Applications

PA1852 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

50 kDa

Calculated molecular weight

40.03kDa

Background of CXADR

CXADR (Coxsackie virus and adenovirus receptor) is a protein that in humans is encoded by the CXADR gene, also known as CAR,CVB3-binding protein, Coxsackievirus B-adenovirus receptor. The CAR cDNA encodes a predicted 365-amino acid polypeptide that contains a single transmembrane domain and is a member of the immunoglobulin superfamily. By Northern blot analysis, they detected highest expression of 1.4-kb and 6-kb CXADR transcripts in pancreas, brain, heart, small intestine, testis, and prostate, lower expression in liver and lung, and no expression in kidney, placenta, peripheral blood leukocytes, thymus, and spleen. In comparison, mouse Cxadr showed highest expression in liver, and lower levels in kidney, heart, lung, and brain. The protein encoded by this gene is a type I membrane receptor for group B coxsackie viruses and subgroup C adenoviruses. Pseudogenes of this gene are found on chromosomes 15, 18, and 21. CAR is strongly expressed in the developing central nervous system. It functions as a homophilic and also as a heterophilic cell adhesion molecule through its interactions with extracellular matrix glycoproteins , such as: fibronectin, agrin, laminin-1 and tenascin-R.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat

Validation Images & Assay Conditions

Gene/Protein Information For CXADR (Source: Uniprot.org, NCBI)

Gene Name

CXADR

Full Name

Coxsackievirus and adenovirus receptor

Weight

40.03kDa

Alternative Names

CAR10Coxsackievirus B-adenovirus receptor; CAR4/6; coxsackie virus and adenovirus receptor; coxsackie virus B receptor; coxsackievirus and adenovirus receptor; CVB3 binding protein; CVB3 BP; CVB3-binding protein; CXADR; HCAR; HCVADR CXADR CAR, CAR4/6, HCAR CXADR Ig-like cell adhesion molecule coxsackievirus and adenovirus receptor|46 kD coxsackievirus and adenovirus receptor (CAR) protein|CVB3-binding protein|HCVADR|coxsackie virus and adenovirus receptor|coxsackievirus B-adenovirus receptor

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on CXADR, check out the CXADR Infographic

CXADR infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for CXADR: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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1 Customer Q&As for Anti-Coxsackie Adenovirus Receptor/CXADR Antibody

Question

We are currently using anti-Coxsackie Adenovirus Receptor/CXADR antibody PA1852 for rat tissue, and we are satisfied with the WB results. The species of reactivity given in the datasheet says human, mouse, rat. Is it possible that the antibody can work on horse tissues as well?

A. Johnson

Verified customer

Asked: 2017-11-06

Answer

The anti-Coxsackie Adenovirus Receptor/CXADR antibody (PA1852) has not been tested for cross reactivity specifically with horse tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in horse you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2017-11-06

Order DetailsPrice
PA1852

100μg

$370
PA1852-10ug

10μg sample (liquid)

$99
PA1852-Biotin

100 μg Biotin conjugated

$570
PA1852-Cy3

100 μg Cy3 conjugated

$570
PA1852-Dylight488

100 μg Dylight488 conjugated

$570
PA1852-Dylight550

100 μg Dylight550 conjugated

$570
PA1852-Dylight594

100 μg Dylight594 conjugated

$570
PA1852-FITC

100 μg FITC conjugated

$570
PA1852-HRP

100 μg HRP conjugated

$570
PA1852-APC

100 μg APC conjugated

$670
PA1852-PE

100 μg PE conjugated

$670
PA1852-carrier-free

Carrier Free

$370

More conjugates/formats

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PA1852
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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