Anti-CTGF Antibody Picoband™

CCN2 antibody

Boster Bio Anti-CTGF Antibody Picoband™ catalog # PB9541. Tested in IHC, WB applications. This antibody reacts with Human, Rat. Cited in 10 publication(s).

Product Info Summary

SKU: PB9541
Size: 100 μg/vial
Reactive Species: Human, Rat
Host: Rabbit
Application: IHC, WB

Product Name

Anti-CTGF Antibody Picoband™

View all CCN2 Antibodies

SKU/Catalog Number

PB9541

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-CTGF Antibody Picoband™ catalog # PB9541. Tested in IHC, WB applications. This antibody reacts with Human, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-CTGF Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # PB9541)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E.coli-derived human CTGF recombinant protein (Position: R58-A349). Human CTGF shares 95.5% and 95.9% amino acid (aa) sequence identity with mouse and rat CTGF, respectively.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PB9541 is reactive to CCN2 in Human, Rat

Applications

PB9541 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

38 kDa

Calculated molecular weight

38.091kDa

Background of CCN2

CTGF, also known as CCN2 or connective tissue growth factor, is a matricellular protein of the CCN family of extracellular matrix-associated heparin-binding proteins (see also CCN intercellular signaling protein). CTGF has important roles in many biological processes, including cell adhesion, migration, proliferation, angiogenesis, skeletal development, and tissue wound repair, and is critically involved in fibrotic disease and several forms of cancers. The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. And the encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, By Heat
Western blot, 0.1-0.5μg/ml, Human, Rat

Validation Images & Assay Conditions

Gene/Protein Information For CCN2 (Source: Uniprot.org, NCBI)

Gene Name

CCN2

Full Name

CCN family member 2

Weight

38.091kDa

Superfamily

CCN family

Alternative Names

CCN family member 2 CCN2 CTGF, HCS24, IGFBP8, NOV2 cellular communication network factor 2 CCN family member 2|IBP-8|IGF-binding protein 8|IGFBP-8|connective tissue growth factor|hypertrophic chondrocyte-specific protein 24|insulin-like growth factor-binding protein 8

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on CCN2, check out the CCN2 Infographic

CCN2 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for CCN2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

PB9541 has been cited in 10 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Xu Q,Liu M,Zhang F,Liu X,Ling S,Chen X,Gu J,Ou W,Liu S,Liu N. Ubiquitin-specific protease 2 regulates Ang Ⅱ-induced cardiac fibroblasts activation by up-regulating cyclin D1 and stabilizing β-catenin in vitro. J Cell Mol Med.2020 Dec 12.doi:10.1111/jcmm.1
Species: Rat
PB9541 usage in article: APP:WB, SAMPLE:CFS, DILUTION:NA

Influence and mechanism of He-Ne laser on scar formation of filtration canal after trabeculectomy in rabbit

PCPA protects against monocrotaline-induced pulmonary arterial remodeling in rats: potential roles of connective tissue growth factor

Inhibition of angiogenesis by arsenic trioxide via TSP-1?TGF-?1-CTGF?VEGF functional module in rheumatoid arthritis

Effect and Mechanism of QiShenYiQi Pill on Experimental Autoimmune Myocarditis Rats

Molecular responses of radiation-induced liver damage in rats

Increased Expression of CCN2 in the Red Flashing Light-Induced Myopia in Guinea Pigs

Advanced Glycation End-Products Induce Connective Tissue Growth Factor-Mediated Renal Fibrosis Predominantly through Transforming Growth Factor ?-Independent Pathway

Role of transforming growth factor-beta signaling pathway in pathogenesis of benign biliary stricture

Chronic sciatic nerve compression induces fibrosis in dorsal root ganglia

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2 Customer Q&As for Anti-CTGF Antibody Picoband™

Question

Is distilled water or PBS(free Mg+ and Ca+) needed to reconstitute the PB9541?

Verified customer

Asked: 2020-10-14

Answer

It is OK to use distilled water or PBS(free Mg+ and Ca+) to reconstitute the Anti-CTGF Antibody Picoband™ (PB9541).

Boster Scientific Support

Answered: 2020-10-14

Question

We are currently using anti-CTGF antibody PB9541 for rat tissue, and we are content with the IHC results. The species of reactivity given in the datasheet says human, rat. Is it true that the antibody can work on monkey tissues as well?

Verified Customer

Verified customer

Asked: 2019-11-11

Answer

The anti-CTGF antibody (PB9541) has not been tested for cross reactivity specifically with monkey tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in monkey you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2019-11-11

Order DetailsPrice
PB9541

100μg

$370
PB9541-10ug

10μg sample (liquid)

$99
PB9541-Biotin

100 μg Biotin conjugated

$570
PB9541-Cy3

100 μg Cy3 conjugated

$570
PB9541-Dylight488

100 μg Dylight488 conjugated

$570
PB9541-Dylight550

100 μg Dylight550 conjugated

$570
PB9541-Dylight594

100 μg Dylight594 conjugated

$570
PB9541-FITC

100 μg FITC conjugated

$570
PB9541-HRP

100 μg HRP conjugated

$570
PB9541-APC

100 μg APC conjugated

$670
PB9541-PE

100 μg PE conjugated

$670
PB9541-carrier-free

Carrier Free

$370

More conjugates/formats

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PB9541
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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