Anti-EAAT2/GLT-1/SLC1A2 Antibody

EAAT2/GLT1 antibody

Boster Bio Anti-EAAT2/GLT-1/SLC1A2 Antibody catalog # RP1065. Tested in IF, IHC, WB applications. This antibody reacts with Mouse, Rat. Cited in 2 publication(s).

Product Info Summary

SKU: RP1065
Size: 100 μg/vial
Reactive Species: Mouse, Rat
Host: Rabbit
Application: IF, IHC, WB

Customers Who Bought This Also Bought

Product Name

Anti-EAAT2/GLT-1/SLC1A2 Antibody

View all EAAT2/GLT1 Antibodies

SKU/Catalog Number

RP1065

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-EAAT2/GLT-1/SLC1A2 Antibody catalog # RP1065. Tested in IF, IHC, WB applications. This antibody reacts with Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-EAAT2/GLT-1/SLC1A2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # RP1065)

Host

Rabbit

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2mg Na2HPO4, 0.05 mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E.coli-derived human EAAT2 recombinant protein (Position: T461-K574). Human EAAT2 shares 96% amino acid (aa) sequence identity with both mouse and rat EAAT2.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

RP1065 is reactive to SLC1A2 in Mouse, Rat

Applications

RP1065 is guaranteed for IF, IHC, WB Boster Guarantee

Observed Molecular Weight

65 kDa

Calculated molecular weight

62.104kDa

Background of EAAT2/GLT1

SLC1A2 is also known as EAAT2 or GLT-1. This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been identified.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Innovating Scientists Reward

If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.

Submit A Review

Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Mouse, Rat
Immunofluorescence, 5 μg/ml, Mouse, Rat

Validation Images & Assay Conditions

Gene/Protein Information For SLC1A2 (Source: Uniprot.org, NCBI)

Gene Name

SLC1A2

Full Name

Excitatory amino acid transporter 2

Weight

62.104kDa

Superfamily

dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family

Alternative Names

EAAT2; GLT1; member 2; SLC1A2; solute carrier family 1 (glial high affinity glutamate transporter), member 2; Solute carrier family 1 member 2 SLC1A2 DEE41, EAAT2, EIEE41, GLT-1, HBGT solute carrier family 1 member 2 excitatory amino acid transporter 2|excitotoxic amino acid transporter 2|glutamate/aspartate transporter II|sodium-dependent glutamate/aspartate transporter 2|solute carrier family 1 (glial high affinity glutamate transporter), member 2

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on SLC1A2, check out the SLC1A2 Infographic

SLC1A2 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for SLC1A2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

RP1065 has been cited in 2 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Song T,Chen W,Chen X,Zhang H,Zou Y,Wu H,Lin F,Ren L,Kang Y,Lei H.Repeated fluoxetine treatment induces transient and long-term astrocytic plasticity in the medial prefrontal cortex of normal adult rats.Prog Neuropsychopharmacol Biol Psychiatry.2021 Jan 20
Species: Rat
RP1065 usage in article: APP:WB, SAMPLE:MPFC TISSUE, DILUTION:1:500

Ding Y, Zhang K, Liu S, Zhang Q, Ma C, Bruce Ic, Zhang X. Exp Ther Med. 2014 Dec;8(6):1909-1913. Epub 2014 Oct 15. Tumor Necrosis Factor-?? Promotes The Expression Of Excitatory Amino-Acid Transporter 2 In Astrocytes: Optimal Concentration And Inc...

Have you used Anti-EAAT2/GLT-1/SLC1A2 Antibody?

Submit a review and receive an Amazon gift card.

  • $25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
  • $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit A Review

Be the first to review Anti-EAAT2/GLT-1/SLC1A2 Antibody

*The first user to submit a review for a product is eligible for Boster's Innovating Scientists Reward, which gives product credits. This is in addition to the gift card reward.

Have a question?

Find answers in Q&As, reviews.

Can't find your answer?

Submit your question

1 Customer Q&As for Anti-EAAT2/GLT-1/SLC1A2 Antibody

Question

We are currently using anti-EAAT2/GLT-1/SLC1A2 antibody RP1065 for human tissue, and we are happy with the WB results. The species of reactivity given in the datasheet says human, mouse, rat. Is it possible that the antibody can work on monkey tissues as well?

Verified Customer

Verified customer

Asked: 2019-10-29

Answer

The anti-EAAT2/GLT-1/SLC1A2 antibody (RP1065) has not been tested for cross reactivity specifically with monkey tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in monkey you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2019-10-29

Order DetailsPrice
RP1065

100μg

$370
RP1065-10ug

10μg sample (liquid)

$99
RP1065-Biotin

100 μg Biotin conjugated

$570
RP1065-Cy3

100 μg Cy3 conjugated

$570
RP1065-Dylight488

100 μg Dylight488 conjugated

$570
RP1065-Dylight550

100 μg Dylight550 conjugated

$570
RP1065-Dylight594

100 μg Dylight594 conjugated

$570
RP1065-FITC

100 μg FITC conjugated

$570
RP1065-HRP

100 μg HRP conjugated

$570
RP1065-APC

100 μg APC conjugated

$670
RP1065-PE

100 μg PE conjugated

$670
RP1065-carrier-free

Carrier Free

$370

More conjugates/formats

Free Secondary Antibody

Choose an option to show lead time.
Get A Quote
Eddy test
In stock
Order Product
RP1065
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

Troubleshooting

troubleshooting-box-image

Download troubleshooting handbooks for IHC, Western blot and ELISA for FREE.

Download Free PDFs Now

Boster Guarantee

Guaranteed product quality

Guaranteed product quality

We promise all of our products perform as described in datasheets.