Product Info Summary
SKU: | A02812-2 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IHC, WB |
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Product info
Product Name
Anti-ERK 5 MAPK7 Antibody
SKU/Catalog Number
A02812-2
Size
100ul
Form
Liquid
Description
Boster Bio Anti-ERK 5 MAPK7 Antibody catalog # A02812-2. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-ERK 5 MAPK7 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02812-2)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant Protein
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A02812-2 is reactive to MAPK7 in Human, Mouse, Rat
Applications
A02812-2 is guaranteed for IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
88.386kDa
Background of ERK5/BMK1
Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway and the steroid hormone signaling pathway. Involved in regulating STAT3 signaling via inhibiting STAT3 DNA-binding and suppressing cell growth.
Jiang-Hong Man, Nucleic Acids Res., Nov 2006; 34: 5552 - 5566.
Amir Sonnenblick, Mol. Cell. Biol., Dec 2004; 24: 10584 - 10592.
Jianyin Long, PNAS, Jan 2004; 101: 99.
Hyun Duk Jang, J. Biol. Chem., Jun 2004; 279: 24873 - 24880.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:1000-2000
IHC 1:200-500
Validation Images & Assay Conditions
Click image to see more details
Figure 2. Immunohistochemistry validation of MAPK7 using Anti-ERK 5 MAPK7 Antibody (A02812-2).
Immunohistochemistry (IHC) analysis of paraffin-embedded Human Breast Carcicnoma using ERK 5 polyclonal antibody.For more protocol information of IHC
Click image to see more details
Figure 1. Western blotting validation for Anti-ERK 5 MAPK7 Antibody A02812-2
Western Blot (WB) analysis of 1) HeLaProtein Target Info & Infographic
Gene/Protein Information For MAPK7 (Source: Uniprot.org, NCBI)
Gene Name
MAPK7
Full Name
Mitogen-activated protein kinase 7
Weight
88.386kDa
Superfamily
protein kinase superfamily
Alternative Names
Big MAP kinase 1; BMK1 kinase; BMK1; BMK-1; BMK1EC 2.7.11.24; EC 2.7.11; ERK5; ERK-5; ERK5MAPK 7; Extracellular signal-regulated kinase 5; extracellular-signal-regulated kinase 5; MAP kinase 7; MAPK7; mitogen-activated protein kinase 7; PRKM7ERK4 MAPK7 BMK1, ERK4, ERK5, PRKM7 mitogen-activated protein kinase 7 mitogen-activated protein kinase 7|BMK-1|BMK1 kinase|ERK-5|MAP kinase 7|MAPK 7|big MAP kinase 1|extracellular-signal-regulated kinase 5
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on MAPK7, check out the MAPK7 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for MAPK7: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-ERK 5 MAPK7 Antibody (A02812-2)
Hello CJ!
No publications found for A02812-2
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