Anti-Estrogen Receptor beta/ESR2 Antibody

ER beta/NR3A2 antibody

Boster Bio Anti-Estrogen Receptor beta/ESR2 Antibody catalog # PA1126. Tested in WB applications. This antibody reacts with Human.

Product Info Summary

SKU: PA1126
Size: 100 μg/vial
Reactive Species: Human
Host: Rabbit
Application: WB

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Product Name

Anti-Estrogen Receptor beta/ESR2 Antibody

View all ER beta/NR3A2 Antibodies

SKU/Catalog Number

PA1126

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Estrogen Receptor beta/ESR2 Antibody catalog # PA1126. Tested in WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Estrogen Receptor beta/ESR2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1126)

Host

Rabbit

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2mg Na2HPO4, 0.05 mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human Estrogen Receptor beta, different from the related rat and mouse sequences by four amino acids.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA1126 is reactive to ESR2 in Human

Applications

PA1126 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

65 kDa

Calculated molecular weight

59.216kDa

Background of ER beta/NR3A2

Estrogen receptor-beta (ESR2) is a member of the superfamily of nuclear receptors, which can transduce extracellular signals into transcriptional responses. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human

Validation Images & Assay Conditions

Gene/Protein Information For ESR2 (Source: Uniprot.org, NCBI)

Gene Name

ESR2

Full Name

Estrogen receptor beta

Weight

59.216kDa

Superfamily

nuclear hormone receptor family

Alternative Names

ER beta; Erb; ER-beta; ESR2; ESR-BETA; ESTRB; estrogen receptor 2 (ER beta); estrogen receptor beta 4; estrogen receptor beta; NR3A2; NR3A2ESRB; Nuclear receptor subfamily 3 group A member 2 ESR2 ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2, ODG8 estrogen receptor 2 estrogen receptor beta|estrogen receptor beta 4|estrogen receptor beta splice variant, ERbeta2delta7|estrogen receptor beta splice variant, ERbeta4delta7|estrogen receptor beta splice variant, ERbeta6|estrogen receptor beta splice variant, ERbeta6delta7|estrogen receptor beta splice variant, ERbeta7|estrogen receptor beta splice variant, ERbeta7delta7|estrogen receptor beta splice variant, ERbetaEx. 4L|estrogen receptor beta splice variant, ERbetaEx. 6L|nuclear receptor subfamily 3 group A member 2|oestrogen receptor beta

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on ESR2, check out the ESR2 Infographic

ESR2 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for ESR2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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1 Customer Q&As for Anti-Estrogen Receptor beta/ESR2 Antibody

Question

We are currently using anti-Estrogen Receptor beta/ESR2 antibody PA1126 for human tissue, and we are content with the WB results. The species of reactivity given in the datasheet says human. Is it possible that the antibody can work on goat tissues as well?

Verified Customer

Verified customer

Asked: 2017-06-12

Answer

The anti-Estrogen Receptor beta/ESR2 antibody (PA1126) has not been validated for cross reactivity specifically with goat tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in goat you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2017-06-12

Order DetailsPrice
PA1126

100μg

$370
PA1126-10ug

10μg sample (liquid)

$99
PA1126-Biotin

100 μg Biotin conjugated

$570
PA1126-Cy3

100 μg Cy3 conjugated

$570
PA1126-Dylight488

100 μg Dylight488 conjugated

$570
PA1126-Dylight550

100 μg Dylight550 conjugated

$570
PA1126-Dylight594

100 μg Dylight594 conjugated

$570
PA1126-FITC

100 μg FITC conjugated

$570
PA1126-HRP

100 μg HRP conjugated

$570
PA1126-APC

100 μg APC conjugated

$670
PA1126-PE

100 μg PE conjugated

$670
PA1126-carrier-free

Carrier Free

$370

More conjugates/formats

Free Secondary Antibody

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PA1126
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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