Anti-FMO3 Antibody Picoband™

FMO3 antibody

Boster Bio Anti-FMO3 Antibody Picoband™ catalog # PB9590. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: PB9590
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: WB

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Product Name

Anti-FMO3 Antibody Picoband™

View all FMO3 Antibodies

SKU/Catalog Number

PB9590

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-FMO3 Antibody Picoband™ catalog # PB9590. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-FMO3 Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # PB9590)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human FMO3, different from the related mouse sequence by eight amino acids, and from the related rat sequence by six amino acids.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PB9590 is reactive to FMO3 in Human, Mouse, Rat

Applications

PB9590 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

60 kDa

Calculated molecular weight

60.033kDa

Background of FMO3

FMO3 (Flavin-containing Monooxygenase 3) is an enzyme that in humans is encoded by the FMO3 gene. The mammalian flavin-containing monooxygenases (FMO) represent a multigene family whose gene products are localized in the endoplasmic reticulum of many tissues. The FMO3 gene contains 1 noncoding and 8 coding exons. And the FMO3 gene is mapped on 1q24.3. Using quantitative RNase protection assays, FMO3 is present in low abundance in fetal liver and lung and in adult kidney and lung, and in much greater abundance in adult liver. By Western blot analysis of human liver microsomal samples ranging from 8 weeks gestation to 18 years of age, FMO1 is the major fetal isoform and FMO3 is the major adult isoform. FMO3 was expressed at intermediate levels until 11 years of age when a gender-independent increase in FMO3 expression was observed during puberty. Sufferers of trimethylaminuria may display a reduced ability to metabolize substrates for FMO3 such as nicotine. FMO3 metabolizes a number of drugs, including amphetamine, clozapine, deprenyl, metamphetamine, tamoxifen, ethionamide, thiacetazone, and sulindac sulfide.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat

Validation Images & Assay Conditions

Gene/Protein Information For FMO3 (Source: Uniprot.org, NCBI)

Gene Name

FMO3

Full Name

Dimethylaniline monooxygenase [N-oxide-forming] 3

Weight

60.033kDa

Superfamily

FMO family

Alternative Names

dimethylaniline monooxygenase [N-oxide-forming] 3; Dimethylaniline oxidase 3; dJ127D3.1; EC 1.14.13.8; flavin containing monooxygenase 3; FMO 3; FMO form 2; FMO II; FMOII; Hepatic flavin-containing monooxygenase 3; hepatic flavin-containing monooxygenase-3; MGC34400; TMAU FMO3 FMOII, TMAU, dJ127D3.1 flavin containing dimethylaniline monoxygenase 3 dimethylaniline monooxygenase [N-oxide-forming] 3|FMO form 2|dimethylaniline oxidase 3|flavin containing monooxygenase 3|hepatic flavin-containing monooxygenase-3|trimethylamine monooxygenase

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on FMO3, check out the FMO3 Infographic

FMO3 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for FMO3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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1 Customer Q&As for Anti-FMO3 Antibody Picoband™

Question

We are currently using anti-FMO3 antibody PB9590 for mouse tissue, and we are content with the WB results. The species of reactivity given in the datasheet says human, mouse, rat. Is it likely that the antibody can work on feline tissues as well?

J. Roberts

Verified customer

Asked: 2017-05-23

Answer

The anti-FMO3 antibody (PB9590) has not been validated for cross reactivity specifically with feline tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in feline you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2017-05-23

Order DetailsPrice
PB9590

100μg

$370
PB9590-10ug

10μg sample (liquid)

$99
PB9590-Biotin

100 μg Biotin conjugated

$570
PB9590-Cy3

100 μg Cy3 conjugated

$570
PB9590-Dylight488

100 μg Dylight488 conjugated

$570
PB9590-Dylight550

100 μg Dylight550 conjugated

$570
PB9590-Dylight594

100 μg Dylight594 conjugated

$570
PB9590-FITC

100 μg FITC conjugated

$570
PB9590-HRP

100 μg HRP conjugated

$570
PB9590-APC

100 μg APC conjugated

$670
PB9590-PE

100 μg PE conjugated

$670
PB9590-carrier-free

Carrier Free

$370

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PB9590
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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