Anti-Phospho-GABAB R1 (Ser923) Antibody

GABA-B R1 antibody

Boster Bio Anti-Phospho-GABAB R1 (Ser923) Antibody (Catalog # P07297). Tested in WB applications. This antibody reacts with Mouse, Rat. Cited in 1 publication(s).

Product Info Summary

SKU: P07297
Size: 100 µl
Reactive Species: Mouse, Rat
Host: Rabbit
Application: WB

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Product Name

Anti-Phospho-GABAB R1 (Ser923) Antibody

View all GABA-B R1 Antibodies

SKU/Catalog Number

P07297

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-Phospho-GABAB R1 (Ser923) Antibody (Catalog # P07297). Tested in WB applications. This antibody reacts with Mouse, Rat.

Storage & Handling

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C. After date of receipt, stable for at least 1 year at -20°C.

Cite This Product

Anti-Phospho-GABAB R1 (Ser923) Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # P07297)

Host

Rabbit

Contents

10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

Clonality

Polyclonal

Clone Number

1B9

Isotype

IgG

Immunogen

Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser923 of the R1-subunit of rat GABAB receptor, conjugated to keyhole limpet hemocyanin (KLH). Immunogen species is Rat.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

P07297 is reactive to GABBR1 in Mouse, Rat

Applications

P07297 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

52 kDa

Calculated molecular weight

108.32kDa

Background of GABA-B R1

Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. There are two major classes of GABA receptors: the GABA-A and the GABA-B subtype of receptors. GABA-B receptors are heterodimeric G protein-coupled receptors that mediate slow synaptic inhibition in the central nervous system. Phosphorylation enhances GABA-B receptor effector coupling (Couve et al., 2004). Phosphorylation of Ser-923 is thought to be important in the regulation of GABA-B receptor function.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Restore with deionized water (or equivalent) for reconstitution volume of 100 µL

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:1000

Validation Images & Assay Conditions

Gene/Protein Information For GABBR1 (Source: Uniprot.org, NCBI)

Gene Name

GABBR1

Full Name

Gamma-aminobutyric acid type B receptor subunit 1

Weight

108.32kDa

Superfamily

G-protein coupled receptor 3 family

Alternative Names

FLJ92613; GABA B R1; GABABR1; GABBR1; GABBR1-3; gamma-aminobutyric acid (GABA) B receptor, 1; gamma-aminobutyric acid type B receptor subunit 1; Gb1; GPRC3A; GPRC3Asubunit 1c; hGB1a; seven transmembrane helix receptor GABBR1 GABABR1-3, GB1, GPRC3A, GABBR1 gamma-aminobutyric acid type B receptor subunit 1 gamma-aminobutyric acid type B receptor subunit 1|GABA-B receptor, R1 subunit|gamma-aminobutyric acid (GABA) B receptor, 1|seven transmembrane helix receptor

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on GABBR1, check out the GABBR1 Infographic

GABBR1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for GABBR1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

P07297 has been cited in 1 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

The Herbal Constituents in An-Gong-Niu-Huang Wan (AGNH) Protect against Cinnabar- and Realgar-Induced Hepatorenal Toxicity and Accumulations of Mercury and Arsenic in Mice

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5 Customer Q&As for Anti-Phospho-GABAB R1 (Ser923) Antibody

Question

Please see the WB image, lot number and protocol we used for cerebellum {eco:0000303 using anti-Phospho-GABAB R1 (Ser923) antibody P07297. Please let me know if you require anything else.

Verified Customer

Verified customer

Asked: 2020-02-19

Answer

Thank you very much for the data. Our lab team are working to resolve this as quickly as possible, and we appreciate your patience and understanding! You have provided everything we needed. Please let me know if there is anything you need in the meantime.

Boster Scientific Support

Answered: 2020-02-19

Question

Is a blocking peptide available for product anti-Phospho-GABAB R1 (Ser923) antibody (P07297)?

K. Baker

Verified customer

Asked: 2019-11-22

Answer

We do provide the blocking peptide for product anti-Phospho-GABAB R1 (Ser923) antibody (P07297). If you would like to place an order for it please contact [email protected] and make a special request.

Boster Scientific Support

Answered: 2019-11-22

Question

Will anti-Phospho-GABAB R1 (Ser923) antibody P07297 work on bovine WB with pubmed:10906333}?

Verified Customer

Verified customer

Asked: 2019-07-16

Answer

Our lab technicians have not validated anti-Phospho-GABAB R1 (Ser923) antibody P07297 on bovine. You can run a BLAST between bovine and the immunogen sequence of anti-Phospho-GABAB R1 (Ser923) antibody P07297 to see if they may cross-react. If the sequence homology is close, then you can perform a pilot test. Keep in mind that since we have not validated bovine samples, this use of the antibody is not covered by our guarantee. However we have an innovator award program that if you test this antibody and show it works in bovine pubmed:10906333} in WB, you can get your next antibody for free.

Boster Scientific Support

Answered: 2019-07-16

Question

you antibody to test anti-Phospho-GABAB R1 (Ser923) antibody P07297 on rat cerebellum {eco:0000303 for research purposes, then I may be interested in using anti-Phospho-GABAB R1 (Ser923) antibody P07297 for diagnostic purposes as well. Is the antibody suitable for diagnostic purposes?

Verified Customer

Verified customer

Asked: 2017-08-16

Answer

The products we sell, including anti-Phospho-GABAB R1 (Ser923) antibody P07297, are only intended for research use. They would not be suitable for use in diagnostic work. If you have the means to develop a product into diagnostic use, and are interested in collaborating with us and develop our product into an IVD product, please contact us for more discussions.

Boster Scientific Support

Answered: 2017-08-16

Question

I see that the anti-Phospho-GABAB R1 (Ser923) antibody P07297 works with WB, what is the protocol used to produce the result images on the product page?

E. Parker

Verified customer

Asked: 2013-11-07

Answer

You can find protocols for WB on the "support/technical resources" section of our navigation menu. If you have any further questions, please send an email to [email protected]

Boster Scientific Support

Answered: 2013-11-07

Order DetailsPrice
P07297

100uL

$465

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