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SKU:MA1047
Pack Size:100μg/vial
Sample Size:30ug for $99, contact us for details
Clonality:Monoclonal
Clone Number:K79bB10
Application:IHC-P
Price: $200.00
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Overview

Product Name Anti-Glucagon Antibody (Monoclonal, K79bB10)
SKU/Catalog Number MA1047
Description Mouse IgG monoclonal antibody for Glucagon, glucagon (GCG) detection. Tested with IHC-P in Human, mouse, rat, rabbit. No cross reactivity with other proteins.
Cite This Product Anti-Glucagon Antibody (Monoclonal, K79bB10) K79bB10 (Boster Biological Technology, Pleasanton CA, USA, Catalog # MA1047)
Replacement Item This antibody may replace the following items: sc-130624|sc-13091|sc-167994|sc-167996|sc-167998|sc-26637|sc-514592|sc-57164|sc-57165|sc-57166|sc-57167|sc-57168|sc-57169|sc-57170|sc-57171|sc-57510|sc-65388|sc-65389|sc-71150|sc-71151|sc-71152|sc-73508|sc-7779|sc-7779-R|sc-7780|sc-7781|sc-7782|sc-80570|sc-80574|sc-80602|sc-80603|sc-80604 from Santa Cruz Biotechnology.
Host Mouse
Isotype Mouse IgG1
Validated Species Human, Mouse, Rabbit, Rat
Predicted Species Monkey

*This antibody is predicted to react with the above species based on antigen sequence similarities. Our Boster Guarantee covers the use of this product with the above species.

Application IHC-P

*Our Boster Guarantee covers the use of this product in the above tested applications.

**For positive and negative control design, consult "Tissue specificity" under Protein Target Info.

Recommended Detection Systems Boster recommends HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P).
*Blocking peptide can be purchased at $50. Contact us for more information
**Boster also offers various secondary antibodies for Immunoflourescecne and IHC. Take advantage of the buy 1 primary antibody get 1 secondary antibody for free promotion for the entire year 2017!
Immunogen Polymerized porcine glucagon.
Cross Reactivity No cross reactivity with other proteins
Pack Size 100μg/vial

Properties

Clonality Monoclonal
Clone Number K79bB10
Form Lyophilized
Contents Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
*carrier free antibody available upon request.
Concentration Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Storage At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
Purification Ascites
Isotype Mouse IgG1

Protein Target Info (Source: Uniprot.org)

You can check the tissue specificity below for information on selecting positive and negative control.

Gene Name Gcg
Protein Name Glucagon
Molecular Weight 20846 MW
Protein Function Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. Plays an important role in initiating and maintaining hyperglycemic conditions in diabetes. .
Tissue Specificity Glucagon is secreted in the A cells of the islets of Langerhans. GLP-1, GLP-2, oxyntomodulin and glicentin are secreted from enteroendocrine cells throughout the gastrointestinal tract. .
Sequence Similarities Belongs to the glucagon family.
Subcellular Localization Secreted.
Uniprot ID P06883
Alternative Names Glucagon;Glicentin;Glicentin-related polypeptide;GRPP;Oxyntomodulin;OXM;OXY;Glucagon;Glucagon-like peptide 1;GLP-1;Glucagon-like peptide 1(7-37);GLP-1(7-37);Glucagon-like peptide 1(7-36);GLP-1(7-36);Glucagon-like peptide 2;GLP-2;Gcg;
Research Areas |signal transduction|growth factors/hormones| stem cells|lineage markers|endoderm| cancer|tumor biomarkers| developmental biology|lineage specification|cancer metabolism|metabolic signaling pathway|integration of energy metabolism| metabolism|pathways and processes|metabolic signaling pathways|energy transfer pathways|integration of energy|types of disease|
*if product is indicated to react with multiple species, protein info is based on the human gene.

Background for Glucagon

Glucagon is a member of a multigene family that includes secretin. Glucagon is a 29-amino acid pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. The human glucagon gene is approximately 9.4 kb long and contains 6 exons and 5 introns, and assigned to 2q36-2q37.

Anti-Glucagon Antibody (Monoclonal, K79bB10) Images

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Anti-Glucagon Antibody (Monoclonal, K79bB10)
Anti-Glucagon antibody (monoclonal), MA1047, IHC(P)
IHC(P): Rat Pancreas Tissue
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Publications

Lan F, Yue X, Han L, Shi Z, Yang Y, Pu P, Yao Z, Kang C. Int J Oncol. 2012 Feb;40(2):519-26. Doi: 10.3892/Ijo.2011.1215. Epub 2011 Sep 28. Genome-Wide Identification Of Tcf7L2/Tcf4 Target Mirnas Reveals A Role For Mir-21 In Wnt-Driven Epithelial C...
Jiang H, Deng Xf, Duan Cm, Chen C, Xiang Jl, Lu Yl, Ma Qf. Lymphology. 2011 Mar;44(1):21-8. Somatostatin Receptors Sstr2 And Sstr5 Are Expressed In The Human Thoracic Duct.
Zhang Y, Ye C, Wang G, Gao Y, Tan K, Zhuo Z, Liu Z, Xia H, Yang D, Li P. Biomed Res Int. 2013;2013:526367. Doi: 10.1155/2013/526367. Epub 2013 May 27. Kidney-Targeted Transplantation Of Mesenchymal Stem Cells By Ultrasound-Targeted Microbubble Des...
Zhang W, Jin H, Hu Y, Yu Y, Li X, Ding Z, Kang Y, Wang B. Hum Gene Ther. 2010 Feb;21(2):171-8. Doi: 10.1089/Hum.2009.095. Protective Response Against Type 1 Diabetes In Nonobese Diabetic Mice After Coimmunization With Insulin And Dna Encoding Proi...
Liu Jj, Raynal S, Bailb?? D, Gausseres B, Carbonne C, Autier V, Movassat J, Kergoat M, Portha B. Biochim Biophys Acta. 2015 May;1852(5):980-91. Doi: 10.1016/J.Bbadis.2015.02.001. Epub 2015 Feb 9. Expression Of The Kynurenine Pathway Enzymes In The ...
Tang Mm, Zhu Qe, Fan Wz, Zhang Sl, Li Dz, Liu Lz, Chen M, Zhang M, Zhou J, Wei Cj. Mol Ther. 2011 Jan;19(1):60-6. Doi: 10.1038/Mt.2010.187. Epub 2010 Sep 14. Intra-Arterial Targeted Islet-Specific Expression Of Sirt1 Protects ?? Cells From Streptoz...

FAQs

Q: Is your western blot protocol provided from the website applicable for all your antibodies? Keyword: applications, WB
A: The protocol is applicable for all our antibodies in WB, the NC Membrane(0.45μm or 0.22μm) and transfer time(70 mins or 50 mins) depends on the protein molecular weight, details can be found in included protocol.
Q: Can I conjugate markers to this antibody? Can I link custom conjugates to this antibody? Keyword: conjugation
A: The antibody is stored with BSA and cannot be conjugated with markers. Carrier free antibodies are available upon request. Please contact support@bosterbio.com
Q: Can you provide monoclonal antibodies carrier free?
A: We cannot.
Q: What are some alternative names that could be used to describe this product?
A: Some common names include but are not limited to glp 1 antibody, glp1 antibody, glp2 antibody