Anti-GTPase HRAS Antibody

HRAS antibody

Boster Bio Anti-GTPase HRAS Antibody catalog # RP1098. Tested in WB applications. This antibody reacts with Human, Mouse.

Product Info Summary

SKU: RP1098
Size: 100 μg/vial
Reactive Species: Human, Mouse
Host: Rabbit
Application: WB

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Product Name

Anti-GTPase HRAS Antibody

View all HRAS Antibodies

SKU/Catalog Number

RP1098

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-GTPase HRAS Antibody catalog # RP1098. Tested in WB applications. This antibody reacts with Human, Mouse.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-GTPase HRAS Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # RP1098)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human GTPase HRAS, identical to the related mouse and rat sequences.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

RP1098 is reactive to HRAS in Human, Mouse

Applications

RP1098 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

21 kDa

Calculated molecular weight

21.298kDa

Background of HRAS

GTPase HRas, also known as transforming protein p21, is an enzyme that in humans is encoded by the HRAS gene. This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human, Mouse

Validation Images & Assay Conditions

Gene/Protein Information For HRAS (Source: Uniprot.org, NCBI)

Gene Name

HRAS

Full Name

GTPase HRas

Weight

21.298kDa

Superfamily

small GTPase superfamily

Alternative Names

Nothing Found HRAS C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV1, RASH1, p21ras, HRAS HRas proto-oncogene, GTPase GTPase HRas|GTP- and GDP-binding peptide B|Ha-Ras1 proto-oncoprotein|Harvey rat sarcoma viral oncogene homolog|Harvey rat sarcoma viral oncoprotein|Ras family small GTP binding protein H-Ras|c-has/bas p21 protein|p19 H-RasIDX protein|transformation gene: oncogene HAMSV|transforming protein p21|v-Ha-ras Harvey rat sarcoma viral oncogene homolog

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on HRAS, check out the HRAS Infographic

HRAS infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for HRAS: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
RP1098

100μg

$370
RP1098-10ug

10μg sample (liquid)

$99
RP1098-Biotin

100 μg Biotin conjugated

$570
RP1098-Cy3

100 μg Cy3 conjugated

$570
RP1098-Dylight488

100 μg Dylight488 conjugated

$570
RP1098-Dylight550

100 μg Dylight550 conjugated

$570
RP1098-Dylight594

100 μg Dylight594 conjugated

$570
RP1098-FITC

100 μg FITC conjugated

$570
RP1098-HRP

100 μg HRP conjugated

$570
RP1098-APC

100 μg APC conjugated

$670
RP1098-PE

100 μg PE conjugated

$670
RP1098-carrier-free

Carrier Free

$370

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RP1098
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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