Anti-HNF1 beta/HNF1B Antibody Picoband™

TCF-2/HNF-1 beta antibody

Boster Bio Anti-HNF1 beta/HNF1B Antibody Picoband™ catalog # PB9597. Tested in WB applications. This antibody reacts with Human, Rat.

Product Info Summary

SKU: PB9597
Size: 100 μg/vial
Reactive Species: Human, Rat
Host: Rabbit
Application: WB

Product Name

Anti-HNF1 beta/HNF1B Antibody Picoband™

View all TCF-2/HNF-1 beta Antibodies

SKU/Catalog Number

PB9597

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-HNF1 beta/HNF1B Antibody Picoband™ catalog # PB9597. Tested in WB applications. This antibody reacts with Human, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-HNF1 beta/HNF1B Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # PB9597)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human HNF1 beta, identical to the related mouse and rat sequences.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PB9597 is reactive to HNF1B in Human, Rat

Applications

PB9597 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

61 kDa

Calculated molecular weight

61.324kDa

Background of TCF-2/HNF-1 beta

HNF1 homeobox B (hepatocyte nuclear factor 1 homeobox B), also known as HNF1B or transcription factor 2 (TCF2), is a human gene. It is a member of the homeodomain-containing superfamily of transcription factors. This gene is mapped to 17q12. The HNF1B protein is believed to form heterodimers with another liver-specific member of this transcription factor family, TCF1. HNF1B functions as both a classic transcriptional activator and as a bookmarking factor that marks target genes for rapid transcriptional reactivation after mitosis. HNF1B also can regulate renal tubulogenesis by controlling expression of SOC3. Mutation of HNF1B that disrupts normal function has been identified as the cause of MODY5 (Maturity-Onset of Diabetes, Type 5).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human, Rat

Validation Images & Assay Conditions

Gene/Protein Information For HNF1B (Source: Uniprot.org, NCBI)

Gene Name

HNF1B

Full Name

Hepatocyte nuclear factor 1-beta

Weight

61.324kDa

Superfamily

HNF1 homeobox family

Alternative Names

FJHN; hepatocyte nuclear factor 1-beta; HNF1 beta A; HNF-1 beta; HNF1 homeobox B; HNF1B; HNF-1B; HNF1beta; HNF-1-beta; HNF2; Homeoprotein LFB3; LFB3; LF-B3; MODY5; MODY5HPC11; TCF2; TCF-2; TCF2transcription factor 2, hepatic; LF-B3; variant hepatic nuclear factor; Transcription factor 2; transcription factor 2, hepatic; Variant hepatic nuclear factor 1; VHNF1 HNF1B ADTKD3, FJHN, HNF-1-beta, HNF-1B, HNF1beta, HNF2, HPC11, LF-B3, LFB3, MODY5, RCAD, T2D, TCF-2, TCF2, VHNF1 HNF1 homeobox B hepatocyte nuclear factor 1-beta|HNF1 beta A|homeoprotein LFB3|transcription factor 2, hepatic

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on HNF1B, check out the HNF1B Infographic

HNF1B infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for HNF1B: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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1 Customer Q&As for Anti-HNF1 beta/HNF1B Antibody Picoband™

Question

We are currently using anti-HNF1 beta/HNF1B antibody PB9597 for human tissue, and we are satisfied with the WB results. The species of reactivity given in the datasheet says human, rat. Is it likely that the antibody can work on monkey tissues as well?

S. Thomas

Verified customer

Asked: 2014-06-03

Answer

The anti-HNF1 beta/HNF1B antibody (PB9597) has not been validated for cross reactivity specifically with monkey tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in monkey you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2014-06-03

Order DetailsPrice
PB9597

100μg

$370
PB9597-10ug

10μg sample (liquid)

$99
PB9597-Biotin

100 μg Biotin conjugated

$570
PB9597-Cy3

100 μg Cy3 conjugated

$570
PB9597-Dylight488

100 μg Dylight488 conjugated

$570
PB9597-Dylight550

100 μg Dylight550 conjugated

$570
PB9597-Dylight594

100 μg Dylight594 conjugated

$570
PB9597-FITC

100 μg FITC conjugated

$570
PB9597-HRP

100 μg HRP conjugated

$570
PB9597-APC

100 μg APC conjugated

$670
PB9597-PE

100 μg PE conjugated

$670
PB9597-carrier-free

Carrier Free

$370

More conjugates/formats

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Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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