Anti-HSP60 Hspd1 Antibody (Monoclonal, LK1)

HSP60 antibody

Boster Bio Anti-HSP60 Hspd1 Antibody (Monoclonal, LK1) catalog # MA1049. Tested in IHC, WB applications. This antibody reacts with Chicken, Human, Mouse, Rat. Cited in 6 publication(s).

Product Info Summary

SKU: MA1049
Size: 100 μg/vial
Reactive Species: Chicken, Human, Mouse, Rat
Host: Mouse
Application: IHC, WB

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Product Name

Anti-HSP60 Hspd1 Antibody (Monoclonal, LK1)

View all HSP60 Antibodies

SKU/Catalog Number

MA1049

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-HSP60 Hspd1 Antibody (Monoclonal, LK1) catalog # MA1049. Tested in IHC, WB applications. This antibody reacts with Chicken, Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-HSP60 Hspd1 Antibody (Monoclonal, LK1) (Boster Biological Technology, Pleasanton CA, USA, Catalog # MA1049)

Host

Mouse

Contents

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Clonality

Monoclonal

Clone Number

LK1

Isotype

Mouse IgG1

Immunogen

Recombinant human heat shock protein 60 (HSP60)

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

MA1049 is reactive to HSPD1 in Chicken, Human, Mouse, Rat

Applications

MA1049 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

65 kDa

Calculated molecular weight

61.055kDa

Background of HSP60

Heat shock 60KD protein (HSP60) is a member of the chaperonin class of protein factors and the nuclear encoded mitochondrial HSP60 is required for the assembly into oligomeric complexes of proteins imported into the mitochondrial matrix. HSP60 is linked head to head comprising approximately 17 kb and consist of 12 exons. HSP60 is a self-molecule, it can downregulate adaptive immune responses by upregulating Tregs innately through TLR2 signaling.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 2-4μg/ml, Human, chicken, rat
Immunohistochemistry (Paraffin-embedded Section), 4-8μg/ml, Human, chicken, mouse, rat, By Heat

Validation Images & Assay Conditions

Gene/Protein Information For HSPD1 (Source: Uniprot.org, NCBI)

Gene Name

HSPD1

Full Name

60 kDa heat shock protein, mitochondrial

Weight

61.055kDa

Superfamily

chaperonin (HSP60) family

Alternative Names

60 kDa chaperonin; Chaperonin 60; cpn60; GROEL; heat shock 60kD protein 1 (chaperonin); heat shock 60kDa protein 1 (chaperonin); Heat shock protein 60; heat shock protein 65; HLD4; HSP60; HSP-60; HSP60SPG13; HSP65; HSPD1; HuCHA60; Mitochondrial matrix protein P1,60 kDa heat shock protein, mitochondrial; P60 lymphocyte protein; short heat shock protein 60 Hsp60s1; spastic paraplegia 13 (autosomal dominant); SPG13 HSPD1 CPN60, GROEL, HLD4, HSP-60, HSP60, HSP65, HuCHA60, SPG13 heat shock protein family D (Hsp60) member 1 60 kDa heat shock protein, mitochondrial|60 kDa chaperonin|P60 lymphocyte protein|chaperonin 60|epididymis secretory sperm binding protein|heat shock 60kDa protein 1 (chaperonin)|heat shock protein 65|mitochondrial matrix protein P1|short heat shock protein 60 Hsp60s1

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on HSPD1, check out the HSPD1 Infographic

HSPD1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for HSPD1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

MA1049 has been cited in 6 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Expression and location of HSP60 and HSP10 in the heart tissue of heat-stressed rats

Hepatic mitochondrial and ER stress induced by defective PPAR? signaling in the pathogenesis of hepatic steatosis

Cui Yd, Du Yz, Lu Mx, Qiang Ck. J Insect Sci. 2010;10:100. Doi: 10.1673/031.010.10001. Cloning Of The Heat Shock Protein 60 Gene From The Stem Borer, Chilo Suppressalis, And Analysis Of Expression Characteristics Under Heat Stress.

Hager L, Li L, Pun H, Liu L, Hossain Ma, Maguire Gf, Naples M, Baker C, Magomedova L, Tam J, Adeli K, Cummins Cl, Connelly Pw, Ng Ds. J Biol Chem. 2012 Jun 8;287(24):20755-68. Doi: 10.1074/Jbc.M112.340919. Epub 2012 Apr 12. Lecithin:Cholesterol Ac...

Li L, Nan P, Zhai S, Wang L, Si S, Chang Z. Mol Cell Biochem. 2014 Feb;387(1-2):143-50. Doi: 10.1007/S11010-013-1879-0. Epub 2013 Nov 21. Molecular Cloning, Characterization, And Expression Of Hsp60 In Caudal Fin Regeneration Of Misgurnus Anguilli...

Li L, Zhai S, Wang L, Si S, Wu H, Chang Z. Fish Shellfish Immunol. 2014 Feb;36(2):401-8. Doi: 10.1016/J.Fsi.2013.12.016. Epub 2013 Dec 29. Hsp60 In Caudal Fin Regeneration From Paramisgurnus Dabryanus: Molecular Cloning And Expression Characteriza...

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Order DetailsPrice
MA1049

100μg

$370
MA1049-10ug

10μg sample (liquid)

$99
MA1049-Biotin

100 μg Biotin conjugated

$570
MA1049-Cy3

100 μg Cy3 conjugated

$570
MA1049-Dylight488

100 μg Dylight488 conjugated

$570
MA1049-Dylight550

100 μg Dylight550 conjugated

$570
MA1049-Dylight594

100 μg Dylight594 conjugated

$570
MA1049-FITC

100 μg FITC conjugated

$570
MA1049-HRP

100 μg HRP conjugated

$570
MA1049-APC

100 μg APC conjugated

$670
MA1049-PE

100 μg PE conjugated

$670
MA1049-carrier-free

Carrier Free

$370

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MA1049
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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