|Validated Species:||Human, Mouse, Rabbit, Rat|
Data & Images
|Product Name||Anti-HSP90 Antibody (Monoclonal, AC-16)|
|Description||Mouse IgG monoclonal antibody for HSP90, heat shock protein 90kDa alpha (cytosolic), class A member 1; heat shock protein 90kDa alpha (cytosolic), class B member 1 (HSP90AA1;HSP90AB1) detection. Tested with WB in Human; mouse; rat; rabbit. No cross reactivity with other proteins.|
|Cite This Product||Anti-HSP90 Antibody (Monoclonal, AC-16) AC-16 (Boster Biological Technology, Pleasanton CA, USA, Catalog # MA1051)|
|Replacement Item||This antibody may replace the following items: sc-160182|sc-160181 from Santa Cruz Biotechnology.|
|Validated Species||Human, Mouse, Rabbit, Rat|
|Predicted Species||Bovine, Monkey|
*This antibody is predicted to react with the above species based on antigen sequence similarities. Our Boster Guarantee covers the use of this product with the above species.
*Our Boster Guarantee covers the use of this product in the above tested applications.
**For positive and negative control design, consult "Tissue specificity" under Protein Target Info.
|Recommended Detection Systems||Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot.
*Blocking peptide can be purchased at $50. Contact us for more information
**Boster also offers various secondary antibodies for Immunoflourescecne and IHC. Take advantage of the buy 1 primary antibody get 1 secondary antibody for free promotion for the entire year 2018!
|Immunogen||Heat shock protein 90(HSP90) from the water mold Achlya ambisexualis.|
|Cross Reactivity||No cross reactivity with other proteins|
|Contents||Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.|
|Concentration||Add 1ml of PBS buffer will yield a concentration of 100ug/ml.|
|Storage||At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.|
Protein Target Info (Source: Uniprot.org)
You can check the tissue specificity below for information on selecting positive and negative control.
|Protein Name||Heat shock protein HSP 90-alpha; Heat shock protein HSP 90-beta|
|Molecular Weight||83281 MW|
|Protein Function||Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity). .|
|Subcellular Localization||Cytoplasm . Melanosome .|
|Alternative Names||Heat shock protein HSP 90-beta;Heat shock 84 kDa;HSP 84;HSP84;Hsp90ab1;Hsp84, Hspcb;|
|Research Areas||signal transduction|protein trafficking|chaperones|heat shock proteins|cancer|tumor biomarkers||