Anti-Human AMPK beta 2 DyLight® 488 conjugated PRKAB2 Antibody(monoclonal, 6G1)

AMPK beta 2/PRKAB2 antibody

Boster Bio Anti-Human AMPK beta 2 DyLight® 488 conjugated PRKAB2 Antibody (monoclonal, 6G1) catalog # M05077-Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human.

Product Info Summary

SKU: M05077-Dyl488
Size: 50ug/vial
Reactive Species: Human
Host: Mouse
Application: Flow Cytometry

Product Name

Anti-Human AMPK beta 2 DyLight® 488 conjugated PRKAB2 Antibody(monoclonal, 6G1)

View all AMPK beta 2/PRKAB2 Antibodies

SKU/Catalog Number

M05077-Dyl488

Size

50ug/vial

Form

Liquid

Description

Boster Bio Anti-Human AMPK beta 2 DyLight® 488 conjugated PRKAB2 Antibody (monoclonal, 6G1) catalog # M05077-Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human.

Storage & Handling

At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Cite This Product

Anti-Human AMPK beta 2 DyLight® 488 conjugated PRKAB2 Antibody(monoclonal, 6G1) (Boster Biological Technology, Pleasanton CA, USA, Catalog # M05077-Dyl488)

Host

Mouse

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Clonality

Monoclonal

Clone Number

6G1

Isotype

IgG2b

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human AMPK beta 2 (56-89aa DKEFVSWQQDLEDSVKPTQQARPTVIRWSEGGKE), different from the related mouse sequence by three amino acids, and from the related rat sequence by two amino acids.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross Reactivity

No cross reactivity with other proteins.

Reactive Species

M05077-Dyl488 is reactive to PRKAB2 in Human

Applications

M05077-Dyl488 is guaranteed for Flow Cytometry Boster Guarantee

Background of AMPK beta 2/PRKAB2

5'-AMP-activated protein kinase subunit beta-2 is an enzyme that in humans is encoded by the PRKAB2 gene. The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. It is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

Flow Cytometry, 1-3μg/1x106 cells

Validation Images & Assay Conditions

Gene/Protein Information For PRKAB2 (Source: Uniprot.Org, NCBI)

Uniprot ID

O43741

Gene ID

5565

Gene Name

PRKAB2

Full Name

5'-AMP-activated protein kinase subunit beta-2

Weight

30.302kDa

Superfamily

5'-AMP-activated protein kinase beta subunit family

Alternative Names

5'-AMP-activated protein kinase, beta-2 subunit; AMPK beta 2; AMPK beta 2,5'-AMP-activated protein kinase subunit beta-2; AMPK beta-2 chain; AMPK subunit beta-2; MGC61468; PRKAB2; protein kinase, AMP-activated, beta 2 non-catalytic subunit PRKAB2 protein kinase AMP-activated non-catalytic subunit beta 2 5-AMP-activated protein kinase subunit beta-2|5-AMP-activated protein kinase, beta-2 subunit|AMP-activated protein kinase beta 2 non-catalytic subunit|AMPK beta 2|AMPK beta-2 chain|AMPK subunit beta-2|protein kinase, AMP-activated, beta 2 non-catalytic subunit

*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".

For more info on PRKAB2, check out the PRKAB2 Infographic

PRKAB2 infographic

We have 30,000+ of these available, one for each gene! check them out.

In this infographic you will see the following information for PRKAB2: database IDs, super-family, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us [email protected]

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M05077-Dyl488
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$415.00

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