Anti-human CD10 MME Monoclonal Antibody PE-Cy7 Conjugated, Flow Validated

Neprilysin/CD10 antibody

Boster Bio Anti-human CD10 MME Monoclonal Antibody PE-Cy7 Conjugated, Flow Validated (Catalog# FC04065-PE-Cy7). Tested in Flow Cytometry application(s). This antibody reacts with Human. Cited in 1 publication(s).

Product Info Summary

SKU: FC04065-PE-Cy7
Size: 100 tests, 200 tests
Reactive Species: Human
Host: Mouse
Application: Flow Cytometry

Product Name

Anti-human CD10 MME Monoclonal Antibody PE-Cy7 Conjugated, Flow Validated

View all Neprilysin/CD10 Antibodies

SKU/Catalog Number

FC04065-PE-Cy7

Size

100 tests, 200 tests

Form

Liquid

Description

Boster Bio Anti-human CD10 MME Monoclonal Antibody PE-Cy7 Conjugated, Flow Validated (Catalog# FC04065-PE-Cy7). Tested in Flow Cytometry application(s). This antibody reacts with Human.

Storage & Handling

Store at 2-8°C. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-human CD10 MME Monoclonal Antibody PE-Cy7 Conjugated, Flow Validated (Boster Biological Technology, Pleasanton CA, USA, Catalog # FC04065-PE-Cy7)

Host

Mouse

Contents

PBS pH 7.2, 0.2% (w/v) BSA, 0.09% (w/v) sodium azide

Clonality

Monoclonal

Clone Number

Clone: FR4D11

Isotype

IgG1,k

Immunogen

Raji cells

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

FC04065-PE-Cy7 is reactive to MME in Human

Applications

FC04065-PE-Cy7 is guaranteed for Flow Cytometry Boster Guarantee

Observed Molecular Weight

68 kDa

Calculated molecular weight

85.514kDa

Background of Neprilysin/CD10

CD10, also known as membrane metallo-endopeptidase, neutral endopeptidase (NEP), Neprilysin, or common acute lymphoblastic leukemia antigen (CALLA), is a zinc-dependent metalloprotease enzyme that degrades a number of small secreted peptides, most notably theamyloid beta peptide whose abnormal misfolding and aggregation in neural tissue has been implicated as a cause of Alzheimer's disease. This gene is localized to human chromosome 3 by study of somatic cell hybrids and regionalized the location to 3q21-q27 by in situ hybridization. By cDNA transfection analysis, CD10 is confirmed as a functional neutral endopeptidase of the type that has previously been called enkephalinase. CD10 has also been called atriopeptidase. Atriopeptidase specifically degrades atrial natriuretic factor. A specific enzyme inhibitor was developed and reported that it had effects similar to those of low-dose ANF infusion. These effects include diuresis, natriuresis, vasodilatation, and suppression of the renin-angiotensin-aldosterone system.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Innovating Scientists Reward

If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.

Submit A Review

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Flow Cytometry, 5μl is enough to stain 1 million PBMCs or 100μl whole blood sample

Validation Images & Assay Conditions

Gene/Protein Information For MME (Source: Uniprot.org, NCBI)

Gene Name

MME

Full Name

Neprilysin

Weight

85.514kDa

Superfamily

peptidase M13 family

Alternative Names

Atriopeptidase; CALLA; CALLAmembrane metallo-endopeptidase (neutral endopeptidase, enkephalinase); CD10 antigen; CD10; CD10); CD10membrane metallo-endopeptidase variant 1; Common acute lymphocytic leukemia antigen; DKFZp686O16152; EC 3.4.24; EC 3.4.24.11; Enkephalinase; EPN; Leu-19; membrane metallo-endopeptidase variant 2; membrane metallo-endopeptidase; MGC126681; MGC126707; MME; NEPmembrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA; Neprilysin; Neutral Endopeptidase 24.11; Neutral endopeptidase; NKH1; SFE; Skin fibroblast elastase MME CALLA, CD10, CMT2T, NEP, SCA43, SFE membrane metalloendopeptidase neprilysin|atriopeptidase|common acute lymphocytic leukemia antigen|membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10)|membrane metallo-endopeptidase variant 1|membrane metallo-endopeptidase variant 2|neprilysin-390|neprilysin-411|neutral endopeptidase 24.11|skin fibroblast elastase

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on MME, check out the MME Infographic

MME infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for MME: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

FC04065-PE-Cy7 has been cited in 1 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

A metanephric adenoma of the kidney associated with polycythemia: A case report

Have you used Anti-human CD10 MME Monoclonal Antibody PE-Cy7 Conjugated, Flow Validated?

Submit a review and receive an Amazon gift card.

  • $25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
  • $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit A Review

Be the first to review Anti-human CD10 MME Monoclonal Antibody PE-Cy7 Conjugated, Flow Validated

*The first user to submit a review for a product is eligible for Boster's Innovating Scientists Reward, which gives product credits. This is in addition to the gift card reward.

Have a question?

Find answers in Q&As, reviews.

Can't find your answer?

Submit your question

0 Customer Q&As for Anti-human CD10 MME Monoclonal Antibody PE-Cy7 Conjugated, Flow Validated

Order DetailsPrice
FC04065-PE-Cy7-100tests

100 tests

$338
FC04065-PE-Cy7-200tests

200 tests

$561

Free Secondary Antibody

Choose an option to show lead time.
Get A Quote
Eddy test
In stock
Order Product
FC04065-PE-Cy7
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$338.00

Troubleshooting

troubleshooting-box-image

Download troubleshooting handbooks for IHC, Western blot and ELISA for FREE.

Download Free PDFs Now

Boster Guarantee

Guaranteed product quality

Guaranteed product quality

We promise all of our products perform as described in datasheets.