Anti-human CD11b Itgam Monoclonal Antibody Unconjugated, Flow Validated

ITGAM antibody

Boster Bio Anti-human CD11b Itgam Monoclonal Antibody Unconjugated, Flow Validated (Catalog# FC00144). Tested in Flow Cytometry application(s). This antibody reacts with Human. Cited in 1 publication(s).

Product Info Summary

SKU: FC00144
Size: 100ug, 500ug
Reactive Species: Human
Host: Mouse
Application: Flow Cytometry

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Product Name

Anti-human CD11b Itgam Monoclonal Antibody Unconjugated, Flow Validated

View all ITGAM Antibodies

SKU/Catalog Number

FC00144

Size

100ug, 500ug

Form

Liquid

Description

Boster Bio Anti-human CD11b Itgam Monoclonal Antibody Unconjugated, Flow Validated (Catalog# FC00144). Tested in Flow Cytometry application(s). This antibody reacts with Human.

Storage & Handling

Store at 2-8°C. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-human CD11b Itgam Monoclonal Antibody Unconjugated, Flow Validated (Boster Biological Technology, Pleasanton CA, USA, Catalog # FC00144)

Host

Mouse

Contents

PBS pH 7.2, 0.1% (w/v) BSA, 0.09% (w/v) sodium azide

Clonality

Monoclonal

Clone Number

Clone: OKM1

Isotype

IgG2b,k

Immunogen

Human PBMC

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

FC00144 is reactive to ITGAM in Human

Applications

FC00144 is guaranteed for Flow Cytometry Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

127.179kDa

Background of ITGAM

ITGAM (Integrin Alpha-M), also called CD11B or Mo1 ALPHA SUBUNIT (MO1A), is one protein subunit that forms the heterodimeric integrin alpha-M beta-2 (alphaMbeta2) molecule. A major surface antigen family on human leukocytes includes complement receptor type 3 (CR3A; also called ITGAM, Mac1, or Mo1), lymphocyte function-associated (LFA) antigen type 1 (ITGAL), and p150, 95 (ITGAX). By in situ hybridization, Corbi et al. (1988) demonstrated that the genes encoding the alpha subunits of LFA1 (ITGAL), Mac1, and p150, 95 (ITGAX), all of which are involved in leukocyte adhesion, constitute a cluster on 16p13.1-p11. Callen et al. (1991) narrowed the assignment to 16p11.2. Inflammation plays an essential role in the initiation and progression of atherosclerosis. Simon et al. (2000) presented evidence that it also has a role in vascular repair after mechanical arterial injury (i.e., percutaneous transluminal coronary angioplasty, or PTCA).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

User needs to optimize the dilution ratio for this antibody.

Validation Images & Assay Conditions

Gene/Protein Information For ITGAM (Source: Uniprot.org, NCBI)

Gene Name

ITGAM

Full Name

Integrin alpha-M

Weight

127.179kDa

Superfamily

integrin alpha chain family

Alternative Names

antigen CD11b (p170); CD11 antigen-like family member B; CD11b antigen; CD11b; Cell surface glycoprotein MAC-1 subunit alpha; Complement component 3 receptor 3 subunit; CR-3 alpha chain; CR3A; CR3AMGC117044; Integrin alpha M; integrin alpha-M; integrin, alpha M (complement component 3 receptor 3 subunit); ITGAM; Leukocyte adhesion receptor MO1; MAC 1; MAC1; MAC-1; Mac1, alpha subunit; MAC1A; Mac-1a; macrophage antigen alpha polypeptide; Mo1, alpha subunit; MO1A; neutrophil adherence receptor alpha-M subunit; Neutrophil adherence receptor; SLEB6 ITGAM CD11B, CR3A, MAC-1, MAC1A, MO1A, SLEB6 integrin subunit alpha M integrin alpha-M|CD11 antigen-like family member B|CR-3 alpha chain|antigen CD11b (p170)|cell surface glycoprotein MAC-1 subunit alpha|complement component 3 receptor 3 subunit|integrin, alpha M (complement component 3 receptor 3 subunit)|leukocyte adhesion receptor MO1|macrophage antigen alpha polypeptide|neutrophil adherence receptor alpha-M subunit

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on ITGAM, check out the ITGAM Infographic

ITGAM infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for ITGAM: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

FC00144 has been cited in 1 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Cloning, characterization, and expression analysis of goat (Capra hircus) phospholipid hydroperoxide glutathione peroxidase (PHGPx)

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3 Customer Q&As for Anti-human CD11b Itgam Monoclonal Antibody Unconjugated, Flow Validated

Question

I was wanting to use your anti-human CD11b Monoclonal antibody Unconjugated, Flow Validated for Flow Cytometry for human bone marrow cell on frozen tissues, but I want to know if it has been validated for this particular application. Has this antibody been validated and is this antibody a good choice for human bone marrow cell identification?

K. Anderson

Verified customer

Asked: 2020-04-20

Answer

It shows on the product datasheet, FC00144 anti-human CD11b Monoclonal antibody Unconjugated, Flow Validated has been validated for Flow Cytometry on human tissues. We have an innovator award program that if you test this antibody and show it works in human bone marrow cell in IHC-frozen, you can get your next antibody for free.

Boster Scientific Support

Answered: 2020-04-20

Question

We want to test anti-human CD11b Monoclonal antibody Unconjugated, Flow Validated FC00144 on human bone marrow cell for research purposes, then I may be interested in using anti-human CD11b Monoclonal antibody Unconjugated, Flow Validated FC00144 for diagnostic purposes as well. Is the antibody suitable for diagnostic purposes?

Verified Customer

Verified customer

Asked: 2018-01-23

Answer

The products we sell, including anti-human CD11b Monoclonal antibody Unconjugated, Flow Validated FC00144, are only intended for research use. They would not be suitable for use in diagnostic work. If you have the means to develop a product into diagnostic use, and are interested in collaborating with us and develop our product into an IVD product, please contact us for more discussions.

Boster Scientific Support

Answered: 2018-01-23

Question

Is this FC00144 anti-human CD11b Monoclonal antibody Unconjugated, Flow Validated reactive to the isotypes of ITGAM?

T. Huang

Verified customer

Asked: 2017-01-03

Answer

The immunogen of FC00144 anti-human CD11b Monoclonal antibody Unconjugated, Flow Validated is Human PBMC. Could you tell me which isotype you are interested in so I can help see if the immunogen is part of this isotype?

Boster Scientific Support

Answered: 2017-01-03

Order DetailsPrice
FC00144-100ug

100ug

$143
FC00144-500ug

500ug

$492

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FC00144
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*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$143.00

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