Anti-human CD13 ANPEP Monoclonal Antibody Unconjugated, Flow Validated

Aminopeptidase N/CD13 antibody

Boster Bio Anti-human CD13 ANPEP Monoclonal Antibody Unconjugated, Flow Validated (Catalog# FC02591). Tested in Flow Cytometry application(s). This antibody reacts with Human.

Product Info Summary

SKU: FC02591
Size: 100ug, 500ug
Reactive Species: Human
Host: Mouse
Application: Flow Cytometry

Product Name

Anti-human CD13 ANPEP Monoclonal Antibody Unconjugated, Flow Validated

View all Aminopeptidase N/CD13 Antibodies

SKU/Catalog Number

FC02591

Size

100ug, 500ug

Form

Liquid

Description

Boster Bio Anti-human CD13 ANPEP Monoclonal Antibody Unconjugated, Flow Validated (Catalog# FC02591). Tested in Flow Cytometry application(s). This antibody reacts with Human.

Storage & Handling

Store at 2-8°C. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-human CD13 ANPEP Monoclonal Antibody Unconjugated, Flow Validated (Boster Biological Technology, Pleasanton CA, USA, Catalog # FC02591)

Host

Mouse

Contents

PBS pH 7.2, 0.1% (w/v) BSA, 0.09% (w/v) sodium azide

Clonality

Monoclonal

Clone Number

Clone: APN/1464

Isotype

IgG1,k

Immunogen

Recombinant human CD13 protein

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

FC02591 is reactive to ANPEP in Human

Applications

FC02591 is guaranteed for Flow Cytometry Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

109.54kDa

Background of Aminopeptidase N/CD13

Alanine aminopeptidase, also known as ANPEP or CD13. is an enzyme that is used as a biomarker to detect damage to the kidneys, and that may be used to help diagnose certain kidney disorders. It is mapped to 15q26.1. Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine, Aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases, and it is also thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Petrovic et al showed that CD13 was required for endothelial cell invasion in response to bradykinin. Inhibition of CD13 abrogated internalization of bradykinin receptor B2 and reduced endothelial cell motility.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Flow Cytometry, 5μl is enough to stain 1 million PBMCs or 100μl whole blood sample

Validation Images & Assay Conditions

Gene/Protein Information For ANPEP (Source: Uniprot.org, NCBI)

Gene Name

ANPEP

Full Name

Aminopeptidase N

Weight

109.54kDa

Superfamily

peptidase M1 family

Alternative Names

alanyl (membrane) aminopeptidase; Alanyl aminopeptidase; Aminopeptidase M; Aminopeptidase N; ANPEP; AP-M; APN; AP-N; CD13 antigen; CD13; CD13APN; EC 3.4.11; EC 3.4.11.2; gp150; LAP1; Microsomal aminopeptidase; Myeloid plasma membrane glycoprotein CD13; p150; PEPN; PEPNhAPN ANPEP APN, CD13, GP150, LAP1, P150, PEPN alanyl aminopeptidase, membrane aminopeptidase N|AP-M|AP-N|alanyl (membrane) aminopeptidase|aminopeptidase M|hAPN|membrane alanyl aminopeptidase|microsomal aminopeptidase|myeloid plasma membrane glycoprotein CD13

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on ANPEP, check out the ANPEP Infographic

ANPEP infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for ANPEP: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
FC02591-100ug

100ug

$147
FC02591-500ug

500ug

$492

Free Secondary Antibody

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FC02591
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$147.00

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