Product Info Summary
SKU: | FC02591-PerCP-Cy5.5 |
---|---|
Size: | 100 tests, 200 tests |
Reactive Species: | Human |
Host: | Mouse |
Application: | Flow Cytometry |
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Product info
Product Name
Anti-human CD13 ANPEP Monoclonal Antibody PerCP-Cy5.5 Conjugated, Flow Validated
View all Aminopeptidase N/CD13 Antibodies
SKU/Catalog Number
FC02591-PerCP-Cy5.5
Size
100 tests, 200 tests
Form
Liquid
Description
Boster Bio Anti-human CD13 ANPEP Monoclonal Antibody PerCP-Cy5.5 Conjugated, Flow Validated (Catalog# FC02591-PerCP-Cy5.5). Tested in Flow Cytometry application(s). This antibody reacts with Human.
Storage & Handling
Store at 2-8°C. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-human CD13 ANPEP Monoclonal Antibody PerCP-Cy5.5 Conjugated, Flow Validated (Boster Biological Technology, Pleasanton CA, USA, Catalog # FC02591-PerCP-Cy5.5)
Host
Mouse
Contents
PBS pH 7.2, 0.2% (w/v) BSA, 0.09% (w/v) sodium azide
Clonality
Monoclonal
Clone Number
Clone: APN/1464
Isotype
IgG1,k
Immunogen
Recombinant human CD13 protein
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
FC02591-PerCP-Cy5.5 is reactive to ANPEP in Human
Applications
FC02591-PerCP-Cy5.5 is guaranteed for Flow Cytometry Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
109.54kDa
Background of Aminopeptidase N/CD13
Alanine aminopeptidase, also known as ANPEP or CD13. is an enzyme that is used as a biomarker to detect damage to the kidneys, and that may be used to help diagnose certain kidney disorders. It is mapped to 15q26.1. Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine, Aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases, and it is also thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Petrovic et al showed that CD13 was required for endothelial cell invasion in response to bradykinin. Inhibition of CD13 abrogated internalization of bradykinin receptor B2 and reduced endothelial cell motility.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
User needs to optimize the dilution ratio for this antibody.
Validation Images & Assay Conditions
Click image to see more details
Lymphocytes gated PBMCs stained with FITC conjugated anti-human CD7 (clone 4H9, red histogram). Lymphocytes gated PBMCs stained with IgG2a FITC isotype control (blue histogram).
Protein Target Info & Infographic
Gene/Protein Information For ANPEP (Source: Uniprot.org, NCBI)
Gene Name
ANPEP
Full Name
Aminopeptidase N
Weight
109.54kDa
Superfamily
peptidase M1 family
Alternative Names
alanyl (membrane) aminopeptidase; Alanyl aminopeptidase; Aminopeptidase M; Aminopeptidase N; ANPEP; AP-M; APN; AP-N; CD13 antigen; CD13; CD13APN; EC 3.4.11; EC 3.4.11.2; gp150; LAP1; Microsomal aminopeptidase; Myeloid plasma membrane glycoprotein CD13; p150; PEPN; PEPNhAPN ANPEP APN, CD13, GP150, LAP1, P150, PEPN alanyl aminopeptidase, membrane aminopeptidase N|AP-M|AP-N|alanyl (membrane) aminopeptidase|aminopeptidase M|hAPN|membrane alanyl aminopeptidase|microsomal aminopeptidase|myeloid plasma membrane glycoprotein CD13
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ANPEP, check out the ANPEP Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ANPEP: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-human CD13 ANPEP Monoclonal Antibody PerCP-Cy5.5 Conjugated, Flow Validated (FC02591-PerCP-Cy5.5)
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No publications found for FC02591-PerCP-Cy5.5
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