Anti-human CD62L SELL Monoclonal Antibody APC Conjugated, Flow Validated

L-Selectin/CD62L antibody

Boster Bio Anti-human CD62L SELL Monoclonal Antibody APC Conjugated, Flow Validated (Catalog# FC00652-APC). Tested in Flow Cytometry application(s). This antibody reacts with Human, Baboon. Cited in 1 publication(s).

Product Info Summary

SKU: FC00652-APC
Size: 100 tests, 200 tests
Reactive Species: Human, Baboon
Host: Mouse
Application: Flow Cytometry

Product Name

Anti-human CD62L SELL Monoclonal Antibody APC Conjugated, Flow Validated

View all L-Selectin/CD62L Antibodies

SKU/Catalog Number

FC00652-APC

Size

100 tests, 200 tests

Form

Liquid

Description

Boster Bio Anti-human CD62L SELL Monoclonal Antibody APC Conjugated, Flow Validated (Catalog# FC00652-APC). Tested in Flow Cytometry application(s). This antibody reacts with Human, Baboon.

Storage & Handling

Store at 2-8°C. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-human CD62L SELL Monoclonal Antibody APC Conjugated, Flow Validated (Boster Biological Technology, Pleasanton CA, USA, Catalog # FC00652-APC)

Host

Mouse

Contents

PBS pH 7.2, 0.2% (w/v) BSA, 0.09% (w/v) sodium azide

Clonality

Monoclonal

Clone Number

Clone: DREG56

Isotype

IgG1,k

Immunogen

PMA-activated human peripheral blood leukocytes

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

FC00652-APC is reactive to SELL in Human, Baboon

Applications

FC00652-APC is guaranteed for Flow Cytometry Boster Guarantee

Observed Molecular Weight

68 kDa

Calculated molecular weight

42.187kDa

Background of L-Selectin/CD62L

L-selectin, also known as CD62L, is a cell adhesion molecule found on leukocytes. It belongs to the selectin family of proteins, which recognize sialylated carbohydrate groups. It is cleaved by ADAM17.SELL (L-selectin)is a cell surface component that is a member of a family of adhesion/homing receptors which play important roles in leukocyte-endothelial cell interactions. The molecule is composed of multiple domains: one homologous to lectins, one to epidermal growth factor, and two to the consensus repeat units found in C3/C4 binding proteins.1L-selectin acts as a "homing receptor" for leukocytes to enter secondary lymphoid tissues via high endothelial venules. Ligands present on endothelial cells will bind to leukocyte expressing L-selectin, slowing leukocyte trafficking through the blood, and facilitating entry into a secondary lymphoid organ at that point2.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

User needs to optimize the dilution ratio for this antibody.

Validation Images & Assay Conditions

Gene/Protein Information For SELL (Source: Uniprot.org, NCBI)

Gene Name

SELL

Full Name

L-selectin

Weight

42.187kDa

Superfamily

selectin/LECAM family

Alternative Names

CD62L antigen; CD62L; gp90-MEL; hLHRc; LAM1; LAM-1; LAM1LECAM1; LECAM1; LEU8; Leu-8; Leukocyte adhesion molecule 1; Leukocyte surface antigen Leu-8; Leukocyte-endothelial cell adhesion molecule 1; LNHR; LNHRTQ1; LSEL; L-Selectin; LYAM1; Lyam-1; LYAM1CD62 antigen-like family member L; Lymph node homing receptor; lymphocyte adhesion molecule 1; pln homing receptor; PLNHR; selectin L; SELL; TQ1 SELL CD62L, LAM1, LECAM1, LEU8, LNHR, LSEL, LYAM1, PLNHR, TQ1 selectin L L-selectin|CD62 antigen-like family member L|gp90-MEL|leukocyte surface antigen Leu-8|leukocyte-endothelial cell adhesion molecule 1|lymph node homing receptor|lymphocyte adhesion molecule 1|pln homing receptor

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on SELL, check out the SELL Infographic

SELL infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for SELL: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

FC00652-APC has been cited in 1 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

HIV-1 Nef and Vpu Interfere with L-Selectin (CD62L) Cell Surface Expression To Inhibit Adhesion and Signaling in Infected CD4+ T Lymphocytes

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Order DetailsPrice
FC00652-APC-100tests

100 tests

$325
FC00652-APC-200tests

200 tests

$511

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