Anti-Human CD68 Monoclonal Antibody, Flow Validated

CD68/SR-D1 antibody

Boster Bio Anti-Human CD68 Monoclonal Antibody Unconjugated Conjugated, Flow Validated (Catalog# FC00602). Tested in Flow Cytometry application(s). This antibody reacts with Human. Cited in 4 publication(s).

Product Info Summary

SKU: FC00602
Size: 100ug, 500ug
Reactive Species: Human
Host: Mouse
Application: Flow Cytometry

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Product Name

Anti-Human CD68 Monoclonal Antibody, Flow Validated

View all CD68/SR-D1 Antibodies

SKU/Catalog Number

FC00602

Size

100ug, 500ug

Form

Liquid, in PBS, pH7.2, <0.09% NaN3 and 0.2% (w/v) BSA

Description

Boster Bio Anti-Human CD68 Monoclonal Antibody Unconjugated Conjugated, Flow Validated (Catalog# FC00602). Tested in Flow Cytometry application(s). This antibody reacts with Human.

Storage & Handling

Store at 2-8°C. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Human CD68 Monoclonal Antibody, Flow Validated (Boster Biological Technology, Pleasanton CA, USA, Catalog # FC00602)

Host

Mouse

Contents

PBS pH 7.2, 0.1% (w/v) BSA, 0.09% (w/v) sodium azide

Clonality

Monoclonal

Clone Number

Clone: KP1

Isotype

IgG1,k

Immunogen

Lysosomal fraction of human alveolar macrophages.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

FC00602 is reactive to CD68 in Human

Applications

FC00602 is guaranteed for Flow Cytometry Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

37.408kDa

Background of CD68/SR-D1

CD2 (cluster of differentiation 2) is a cell adhesion molecule found on the surface of T cells and natural killer (NK) cells. It has also been called T-cell surface antigen T11/Leu-5, LFA-2, LFA-3 receptor, erythrocyte receptor and rosette receptor. Monoclonal antibodies directed against CD2 inhibit the formation of rosettes with sheep erythrocytes, indicating that CD2 is the erythrocyte receptor or is closely associated with it. It is one of the earliest T-cell markers, being present on more than 95% of thymocytes; it is also found on some natural killer cells but not on B lymphocytes. Due to its structural characteristics, CD2 is a member of the immunoglobulin superfamily; it possesses two immunoglobulin-like domains in its extracellular portionThe localization of CD2 to 1p13 was established by in situ hybridization. By Southern blotting of DNA from a panel of somatic cell hybrids, Clayton et al. (1988) assigned the CD2 gene to human chromosome 1 and murine chromosome 3.CD2 interacts with other adhesion molecules, such as lymphocyte function-associated antigen-3 (LFA-3/CD58) in humans, or CD48 in rodents, which are expressed on the surfaces of other cells. With the use of transgenic mice, such an LCR was identified within the 3-prime flanking region of the human CD2 gene.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

User needs to optimize the dilution ratio for this antibody.

Validation Images & Assay Conditions

Gene/Protein Information For CD68 (Source: Uniprot.org, NCBI)

Gene Name

CD68

Full Name

Macrosialin

Weight

37.408kDa

Superfamily

LAMP family

Alternative Names

CD68 antigenmacrophage antigen CD68; CD68 molecule; CD68; DKFZp686M18236; gp110; Macrosialin; SCARD1; scavenger receptor class D, member 1; SRD1; SR-D1 CD68 GP110, LAMP4, SCARD1 CD68 molecule macrosialin|CD68 antigen|macrophage antigen CD68|scavenger receptor class D, member 1

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on CD68, check out the CD68 Infographic

CD68 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for CD68: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

FC00602 has been cited in 4 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Targeting Src attenuates peritoneal fibrosis and inhibits the epithelial to mesenchymal transition

PTEN inhibits macrophage polarization from M1 to M2 through CCL2 and VEGF-A reduction and NHERF-1 synergism

Pang Y, Zhang Y, Huang L, Xu L, Wang K, Wang D, Guan L, Zhang Y, Yu F, Chen Z, Xie X. Int J Mol Sci. 2017 Dec 19;18(12). pii: E2766. doi: 10.3390/ijms18122766. Effects and Mechanisms of Total Flavonoids from Blumea balsamifera (L.) DC. on Skin Wou...

Peng K, Liu L, Wei D, Lv Y, Wang G, Xiong W, Wang X, Altaf A, Wang L, He D, Wang H, Qu P. Int J Mol Med. 2015 May;35(5):1179-88. Doi: 10.3892/Ijmm.2015.2129. Epub 2015 Mar 9. P2X7R Is Involved In The Progression Of Atherosclerosis By Promoting Nlr...

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1 Customer Q&As for Anti-Human CD68 Monoclonal Antibody, Flow Validated

Question

What Are CD68 Macrophages?

Verified customer

Asked: 2021-10-20

Answer

CD68 is a protein highly expressed by cells in the monocyte lineage by circulating macrophages, and by tissue macrophages such as Kupffer cells, microglia.

Boster Scientific Support

Answered: 2021-10-20

Order DetailsPrice
FC00602-100ug

100ug

$147
FC00602-500ug

500ug

$492

Free Secondary Antibody

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FC00602
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$147.00

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