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Product Info Summary
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Anti-human CD8 Cd8a Monoclonal Antibody Unconjugated, Flow Validated
Boster Bio Anti-human CD8 Cd8a Monoclonal Antibody Unconjugated, Flow Validated catalog # FC02236. Tested in Flow Cytometry applications. This antibody reacts with Human.
Storage & Handling
Store at 4°C for one year. Do not freeze.
Cite This Product
Anti-human CD8 Cd8a Monoclonal Antibody Unconjugated, Flow Validated (Boster Biological Technology, Pleasanton CA, USA, Catalog # FC02236)
PBS, pH7.2, 0.09% NaN3
FC02236 is reactive to Cd8a in Human
FC02236 is guaranteed for Flow Cytometry Boster Guarantee
Background of CD8
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. It is mapped to 2p11.2. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene also encodes the CD8 alpha chain isoforms.
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.
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Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.
User need to optimize the dilution ratio for this antibody
Validation Images & Assay Conditions
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PBMCs lymphocytes stained with purified antiuman CD8 (clone OKT8) followed by Goat antiouse IgG (H+L) Alexa Fluor 488 (red histogram). PBMCs lymphocytes stained with only Goat antiouse IgG (H+L) Alexa Fluor 488 (Blue histogram).
Gene/Protein Information For Cd8a (Source: Uniprot.org, NCBI)
T-cell surface glycoprotein CD8 alpha chain
53-6.7 CD8 Alpha; 53-6.7 CD8 Aplha; 53-6.7 CD8; 53-6.7 Clone; 53-6.7; CD8; CD8; CD8a molecule; CD8A; Cytotoxic T cell marker; Cytotoxic T lymphocyte marker; LEU2; p32; T cell marker Cd8a|BB154331, Ly-, Ly-2, Ly-3, Ly-35, Ly-B, Lyt-, Lyt-2|CD8 antigen, alpha chain|T-cell surface glycoprotein CD8 alpha chain|Lyt-2.1 lymphocyte differentiation antigen (AA at 100)|T-cell surface glycoprotein Lyt-2*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".
For more info on Cd8a, check out the Cd8a Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Cd8a: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected]
Specific Publications For Anti-human CD8 Cd8a Monoclonal Antibody Unconjugated, Flow Validated (FC02236)
FC02236 has been cited in 2 publications:
*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.
Effect of Hejie decoction on T cell immune state of chronic hepatitis B patients
Xu Y, Tan X, Wang D, Wang W, Li Y, Wu M, Chen S, Wu Y, Tan C. Int J Mol Med. 2015 Jun;35(6):1501-10. Doi: 10.3892/Ijmm.2015.2154. Epub 2015 Mar 24. Elevated Survivin Expression In Peripheral Blood Mononuclear Cells Is Central To Collateral Formati...
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