Anti-Human CRM1 DyLight® 488 conjugated XPO1 Antibody (monoclonal, 5G3)

CRM1 antibody

Boster Bio Anti-Human CRM1 DyLight® 488 conjugated XPO1 Antibody (monoclonal, 5G3) catalog # M01180-Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human.

Product Info Summary

SKU: M01180-Dyl488
Size: 100 μg/vial
Reactive Species: Human
Host: Mouse
Application: Flow Cytometry

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Product Name

Anti-Human CRM1 DyLight® 488 conjugated XPO1 Antibody (monoclonal, 5G3)

View all CRM1 Antibodies

SKU/Catalog Number

M01180-Dyl488

Size

100 μg/vial

Form

Liquid

Description

Boster Bio Anti-Human CRM1 DyLight® 488 conjugated XPO1 Antibody (monoclonal, 5G3) catalog # M01180-Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human.

Storage & Handling

At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Cite This Product

Anti-Human CRM1 DyLight® 488 conjugated XPO1 Antibody (monoclonal, 5G3) (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01180-Dyl488)

Host

Mouse

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Clonality

Monoclonal

Clone Number

5G3

Isotype

Mouse IgG2b

Immunogen

E.coli-derived human CRM1 recombinant protein (Position: N966-D1071). Human CRM1 shares 93.4% and 91.5% amino acid (aa) sequence identity with mouse and rat CRM1, respectively.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

M01180-Dyl488 is reactive to XPO1 in Human

Applications

M01180-Dyl488 is guaranteed for Flow Cytometry Boster Guarantee

Observed Molecular Weight

39 kDa

Calculated molecular weight

123.386kDa

Background of CRM1

Exportin 1 (XPO1), also known as chromosomal maintenance 1 (CRM1), is an eukaryotic protein that mapped to human chromosome 2p16 by fluorescence in situ hybridization. This protein mediates leucine-rich nuclear export signal (NES)-dependent protein transport. It specifically inhibits the nuclear export of Rev and U snRNAs. Additionally, this protein is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. It also regulates NFAT and AP-1.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500μg/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Flow Cytometry, 1-3μg/1x106 cells

Validation Images & Assay Conditions

Gene/Protein Information For XPO1 (Source: Uniprot.org, NCBI)

Gene Name

XPO1

Full Name

Exportin-1

Weight

123.386kDa

Superfamily

exportin family

Alternative Names

Chromosome region maintenance 1 protein homolog; DKFZp686B1823; emb; exp1; exportin 1 (CRM1 homolog, yeast); exportin 1 (CRM1, yeast, homolog); Exportin-1 (required for chromosome region maintenance); exportin-1; yeast, homolog XPO1 CRM-1, CRM1, emb, exp1 exportin 1 exportin-1|chromosome region maintenance 1 homolog|chromosome region maintenance 1 protein homolog|exportin 1 (CRM1 homolog, yeast)|exportin-1 (required for chromosome region maintenance)

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on XPO1, check out the XPO1 Infographic

XPO1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for XPO1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
M01180-Dyl488

100μg

$515
M01180-Dyl488-carrier-free

Carrier Free

$515

Free Secondary Antibody

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M01180-Dyl488
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$515.00

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