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Anti-Human NFAT2 DyLight® 488 conjugated NFATC1 Antibody
Boster Bio Anti-Human NFAT2 DyLight® 488 conjugated NFATC1 Antibody catalog # A00340-Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human.
Storage & Handling
At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Cite This Product
Anti-Human NFAT2 DyLight® 488 conjugated NFATC1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00340-Dyl488)
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
E. coli-derived human NFAT2 recombinant protein (Position: Q589-K652).
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
No cross reactivity with other proteins.
A00340-Dyl488 is reactive to NFATC1 in Human
A00340-Dyl488 is guaranteed for Flow Cytometry Boster Guarantee
Background of NFATC1/NFAT2
NFATC1 (Nuclear factor of activated T-cells, cytoplasmic 1), also known as NFATC or NFAT2, is a protein that in humans is encoded by the NFATC1 gene. And it is also a component of the nuclear factor of activated T cells DNA-binding transcription complex. The NFATC1 gene is mapped on 18q23. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. NFATC1 was not detected in brain, liver, or kidney. NFATC1 is an inducible nuclear component which functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. The solution structure of the binary complex formed between the core DNA-binding domain of human NFATC1 and the 12-bp oligonucleotide duplex containing the ARRE2 DNA site from the IL2 promoter. Nfatc1 was expressed exclusively in mouse hair follicle stem cells, and using gain- and loss-of-function approaches, and Nfatc1 inhibited stem cell activation.
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.
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Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.
Flow Cytometry, 1-3μg/1x106 cells
Validation Images & Assay Conditions
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Boster Kit Box
Gene/Protein Information For NFATC1 (Source: Uniprot.org, NCBI)
Nuclear factor of activated T-cells, cytoplasmic 1
MGC138448; NFAT transcription complex cytosolic component; NFAT2; NFAT2cytoplasmic 1; NFATC; NF-ATC; NFATC1; NF-ATc1; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 NFATC1 NF-ATC, NF-ATc1.2, NFAT2, NFATc nuclear factor of activated T cells 1 nuclear factor of activated T-cells, cytoplasmic 1|NFAT transcription complex cytosolic component|nuclear factor of activated T-cells c|nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".
For more info on NFATC1, check out the NFATC1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for NFATC1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected]
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