Anti-JAB1/COPS5 Antibody Picoband™

JAB1 antibody

Boster Bio Anti-JAB1/COPS5 Antibody Picoband™ catalog # PB9490. Tested in Flow Cytometry, IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: PB9490
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: Flow Cytometry, IF, IHC, IHC-F, ICC, WB

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Product Name

Anti-JAB1/COPS5 Antibody Picoband™

View all JAB1 Antibodies

SKU/Catalog Number

PB9490

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-JAB1/COPS5 Antibody Picoband™ catalog # PB9490. Tested in Flow Cytometry, IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-JAB1/COPS5 Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # PB9490)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E.coli-derived human JAB1 recombinant protein (Position: M8-S334). Human JAB1 shares 99.4% amino acid (aa) sequence identity with mouse JAB1.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PB9490 is reactive to COPS5 in Human, Mouse, Rat

Applications

PB9490 is guaranteed for Flow Cytometry, IF, IHC, IHC-F, ICC, WB Boster Guarantee

Observed Molecular Weight

38 kDa

Calculated molecular weight

37.579kDa

Background of JAB1

COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis), also known as COPS5 or JAB1, is a gene conserved from humans to Saccharomyces cerevisiae. It is a member of the MOV34 family. COPS5 is mapped to 8q13.1. The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. COPS5 can interact with the cytoplasmic domain of the beta-2 subunit of the alpha-L/beta-2 integrin LFA1, and it is the only protein demonstrated to interact with MIF. COPS5, VHL, and TRC8 proteins appear to be linked both physically and functionally, and all 3 may participate in the development of kidney cancer. In addition to that, COPS5 is an essential cofactor for the apoptotic function of E2F1.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Mouse, Rat, By Heat
Immunohistochemistry (Frozen Section), 0.5-1μg/ml, Human
Immunocytochemistry/Immunofluorescence, 2μg/ml, Human
Flow Cytometry, 1-3μg/1x106 cells, Human

Validation Images & Assay Conditions

Gene/Protein Information For COPS5 (Source: Uniprot.org, NCBI)

Gene Name

COPS5

Full Name

COP9 signalosome complex subunit 5

Weight

37.579kDa

Superfamily

peptidase M67A family

Alternative Names

COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis); COP9 signalosome complex subunit 5; COPS5; CSN5; CSN5COP9 (constitutive photomorphogenic, Arabidopsis, homolog) subunit 5; EC 3.4; JAB1; JAB138 kDa Mov34 homolog; Jun activation domain-binding protein 1; MOV-34; SGN5; SGN5MGC3149; Signalosome subunit 5 COPS5 CSN5, JAB1, MOV-34, SGN5 COP9 signalosome subunit 5 COP9 signalosome complex subunit 5|38 kDa Mov34 homolog|COP9 constitutive photomorphogenic homolog subunit 5|jun activation domain-binding protein 1|signalosome subunit 5|testis secretory sperm-binding protein Li 231m

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on COPS5, check out the COPS5 Infographic

COPS5 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for COPS5: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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1 Customer Q&As for Anti-JAB1/COPS5 Antibody Picoband™

Question

We are currently using anti-JAB1/COPS5 antibody PB9490 for mouse tissue, and we are content with the IF results. The species of reactivity given in the datasheet says human, mouse, rat. Is it true that the antibody can work on pig tissues as well?

N. Mangal

Verified customer

Asked: 2013-09-26

Answer

The anti-JAB1/COPS5 antibody (PB9490) has not been tested for cross reactivity specifically with pig tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in pig you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2013-09-26

Order DetailsPrice
PB9490

100μg

$370
PB9490-10ug

10μg sample (liquid)

$99
PB9490-Biotin

100 μg Biotin conjugated

$570
PB9490-Cy3

100 μg Cy3 conjugated

$570
PB9490-Dylight488

100 μg Dylight488 conjugated

$570
PB9490-Dylight550

100 μg Dylight550 conjugated

$570
PB9490-Dylight594

100 μg Dylight594 conjugated

$570
PB9490-FITC

100 μg FITC conjugated

$570
PB9490-HRP

100 μg HRP conjugated

$570
PB9490-APC

100 μg APC conjugated

$670
PB9490-PE

100 μg PE conjugated

$670
PB9490-carrier-free

Carrier Free

$370

More conjugates/formats

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Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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