Anti-LOX-1/OLR1 Antibody Picoband™

LOX-1/OLR1 antibody

Boster Bio Anti-LOX-1/OLR1 Antibody Picoband™ catalog # A00760-1. Tested in WB applications. This antibody reacts with Human.

Product Info Summary

SKU: A00760-1
Size: 100 μg/vial
Reactive Species: Human
Host: Rabbit
Application: WB

Product Name

Anti-LOX-1/OLR1 Antibody Picoband™

View all LOX-1/OLR1 Antibodies

SKU/Catalog Number

A00760-1

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-LOX-1/OLR1 Antibody Picoband™ catalog # A00760-1. Tested in WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-LOX-1/OLR1 Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00760-1)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human LOX-1/OLR1, different from the related rat sequence by thirteen amino acids.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

A00760-1 is reactive to OLR1 in Human

Applications

A00760-1 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

38 kDa

Calculated molecular weight

30.959kDa

Background of LOX-1/OLR1

OLR1 (oxidized low density lipoprotein (lectin-like) receptor 1) also called CLEC8A, LOX-1, SCARE1, is a receptor protein which belongs to the C-type lectin superfamily. The OLR1 gene encodes a cell-surface endocytosis receptor for oxidized low density lipoprotein (OxLDL). This gene is mapped on 12p13.2. Incubation of the cells with LDL had no effect on LOX1 expression, but incubation with OxLDL resulted in a dose-dependent increase in LOX1 mRNA and protein expression; however, very high concentrations of OxLDL caused a decrease in OxLDL expression, perhaps indicating toxic effects on endothelial cells. LOX1 was also expressed in macrophages, but not in vascular smooth muscle cells. The findings suggested a role for LOX1 in the pathophysiology of atherosclerotic cardiovascular disease. LOX1 expression was detected in all choroidal neovascular membranes, regardless of structure, whereas there was no evidence of LOX1 within the posterior segments of normal eyes. LOX1 plays an active role in the pathogenesis of choroidal neovascularization, especially in ARMD.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human

Validation Images & Assay Conditions

Gene/Protein Information For OLR1 (Source: Uniprot.org, NCBI)

Gene Name

OLR1

Full Name

Oxidized low-density lipoprotein receptor 1

Weight

30.959kDa

Alternative Names

CLEC8A; CLEC8ASLOX1; C-type lectin domain family 8 member A; hLOX-1; Lectin-like oxidized LDL receptor 1; Lectin-like oxLDL receptor 1; Lectin-type oxidized LDL receptor 1; LOX1; LOX-1; LOX1ox LDL receptor 1; LOXIN; OLR1; oxidised low density lipoprotein (lectin-like) receptor 1; oxidized low density lipoprotein (lectin-like) receptor 1; oxidized low-density lipoprotein receptor 1; oxidized low-density lipoprotein receptor 1, soluble form; Ox-LDL receptor 1; SCARE1; scavenger receptor class E, member 1; SR-E1 OLR1 CLEC8A, LOX1, LOXIN, SCARE1, SLOX1 oxidized low density lipoprotein receptor 1 oxidized low-density lipoprotein receptor 1|C-type lectin domain family 8 member A|hLOX-1|lectin-type oxidized LDL receptor 1|ox LDL receptor 1|oxidized low density lipoprotein (lectin-like) receptor 1|oxidized low-density lipoprotein receptor 1, soluble form|scavenger receptor class E, member 1

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on OLR1, check out the OLR1 Infographic

OLR1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for OLR1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A00760-1

100μg

$370
A00760-1-10ug

10μg sample (liquid)

$99
A00760-1-Biotin

100 μg Biotin conjugated

$570
A00760-1-Cy3

100 μg Cy3 conjugated

$570
A00760-1-Dylight488

100 μg Dylight488 conjugated

$570
A00760-1-Dylight550

100 μg Dylight550 conjugated

$570
A00760-1-Dylight594

100 μg Dylight594 conjugated

$570
A00760-1-FITC

100 μg FITC conjugated

$570
A00760-1-HRP

100 μg HRP conjugated

$570
A00760-1-APC

100 μg APC conjugated

$670
A00760-1-PE

100 μg PE conjugated

$670
A00760-1-carrier-free

Carrier Free

$370

More conjugates/formats

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A00760-1
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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