Anti-LRP1/Lrp 1 Cluster Ii Rabbit Monoclonal Antibody

LRP1 antibody

Boster Bio Anti-LRP1/Lrp 1 Cluster Ii Rabbit Monoclonal Antibody catalog # M00829. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: M00829
Size: 100 μl
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: Flow Cytometry, IP, IF, IHC, ICC, WB

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Product Name

Anti-LRP1/Lrp 1 Cluster Ii Rabbit Monoclonal Antibody

View all LRP1 Antibodies

SKU/Catalog Number

M00829

Size

100 μl

Form

Liquid

Description

Boster Bio Anti-LRP1/Lrp 1 Cluster Ii Rabbit Monoclonal Antibody catalog # M00829. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-LRP1/Lrp 1 Cluster Ii Rabbit Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00829)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Clonality

Monoclonal

Clone Number

BDC-12

Isotype

Rabbit IgG

Immunogen

A synthesized peptide derived from human LRP1

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

Detects ~20kDa. Does not cross-react with αB-crystallin, βL-crystallin, ΒH- crystallin, γ-crystallin, HSP25, HSP27 or HSP47 proteins.

Reactive Species

M00829 is reactive to LRP1 in Human, Mouse, Rat

Applications

M00829 is guaranteed for Flow Cytometry, IP, IF, IHC, ICC, WB Boster Guarantee

Observed Molecular Weight

20 kDa

Calculated molecular weight

504.606kDa

Background of LRP1

Dynamin-related GTPase required for mitochondrial fusion and regulation of apoptosis. May form a diffusion barrier for proteins stored in mitochondrial cristae. Proteolytic processing in response to intrinsic apoptotic signals may lead to disassembly of OPA1 oligomers and release of the caspase activator cytochrome C (CYCS) into the mitochondrial intermembrane space.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:10000-1:20000
IHC 1:50-1:100
ICC/IF 1:50-1:100
IP 1:30
FC 1:50

Validation Images & Assay Conditions

Gene/Protein Information For LRP1 (Source: Uniprot.org, NCBI)

Gene Name

LRP1

Full Name

Prolow-density lipoprotein receptor-related protein 1

Weight

504.606kDa

Superfamily

LDLR family

Alternative Names

A2MR; Alpha-2-Macroglobulin Receptor; APOER; Apolipoprotein E receptor; APR; CD91 antigen; CD91; EC 1.1.1.94; EC 3.4.21.9; IGFBP3R; low density lipoprotein receptor-related protein 1; LRP; LRP-1; LRP1A; prolow-density lipoprotein receptor-related protein 1; TbetaR-V/LRP-1/IGFBP-3 receptor; TGFBR5; type V tgf-beta receptor LRP1 A2MR, APOER, APR, CD91, IGFBP-3R, IGFBP3R, IGFBP3R1, KPA, LRPA, TGFBR5, LRP1 LDL receptor related protein 1 prolow-density lipoprotein receptor-related protein 1|TbetaR-V/LRP-1/IGFBP-3 receptor|alpha-2-macroglobulin receptor|apolipoprotein E receptor|low density lipoprotein receptor-related protein 1|type V tgf-beta receptor

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on LRP1, check out the LRP1 Infographic

LRP1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for LRP1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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5 Customer Q&As for Anti-LRP1/Lrp 1 Cluster Ii Rabbit Monoclonal Antibody

Question

We are currently using anti-LRP1/Lrp 1 Cluster Ii Rabbit Monoclonal antibody M00829 for rat tissue, and we are satisfied with the WB results. The species of reactivity given in the datasheet says human, mouse, rat. Is it likely that the antibody can work on horse tissues as well?

Verified Customer

Verified customer

Asked: 2020-01-29

Answer

The anti-LRP1/Lrp 1 Cluster Ii Rabbit Monoclonal antibody (M00829) has not been tested for cross reactivity specifically with horse tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in horse you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2020-01-29

Question

Is a blocking peptide available for product anti-LRP1/Lrp 1 Cluster Ii Rabbit Monoclonal antibody (M00829)?

Verified Customer

Verified customer

Asked: 2019-07-30

Answer

We do provide the blocking peptide for product anti-LRP1/Lrp 1 Cluster Ii Rabbit Monoclonal antibody (M00829). If you would like to place an order for it please contact [email protected] and make a special request.

Boster Scientific Support

Answered: 2019-07-30

Question

Thank you for helping with my inquiry over the phone. Here are the WB image, lot number and protocol we used for placenta using anti-LRP1/Lrp 1 Cluster Ii Rabbit Monoclonal antibody M00829. Let me know if you need anything else.

Verified Customer

Verified customer

Asked: 2018-08-06

Answer

Thanks for the data. You have provided everything we needed. Our lab team are working to resolve your inquiry as quickly as possible, and we appreciate your patience and understanding! Please let me know if there is anything you need in the meantime.

Boster Scientific Support

Answered: 2018-08-06

Question

Is this M00829 anti-LRP1/Lrp 1 Cluster Ii Rabbit Monoclonal antibody reactive to the isotypes of LRP1?

Verified Customer

Verified customer

Asked: 2017-11-29

Answer

The immunogen of M00829 anti-LRP1/Lrp 1 Cluster Ii Rabbit Monoclonal antibody is A synthesized peptide derived from human LRP1. Could you tell me which isotype you are interested in so I can help see if the immunogen is part of this isotype?

Boster Scientific Support

Answered: 2017-11-29

Question

Does anti-LRP1/Lrp 1 Cluster Ii Rabbit Monoclonal antibody M00829 work on primate IHC with plasma?

J. Anderson

Verified customer

Asked: 2013-01-24

Answer

Our lab technicians have not validated anti-LRP1/Lrp 1 Cluster Ii Rabbit Monoclonal antibody M00829 on primate. You can run a BLAST between primate and the immunogen sequence of anti-LRP1/Lrp 1 Cluster Ii Rabbit Monoclonal antibody M00829 to see if they may cross-react. If the sequence homology is close, then you can perform a pilot test. Keep in mind that since we have not validated primate samples, this use of the antibody is not covered by our guarantee. However we have an innovator award program that if you test this antibody and show it works in primate plasma in IHC, you can get your next antibody for free.

Boster Scientific Support

Answered: 2013-01-24

Order DetailsPrice
M00829

100μL

$370
M00829-30ul

30μL sample

$99
M00829-carrier-free

Carrier Free

$370

More conjugates/formats

Free Secondary Antibody

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M00829
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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