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SKU:MA1057
Pack Size:100μg/vial
Sample Size:30ug for $99, contact us for details
Clonality:Monoclonal
Clone Number:HM-2
Application:IHC-P, WB
Price: $200.00
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Overview

Product Name Anti-MAP2 Antibody (Monoclonal, HM-2)
SKU/Catalog Number MA1057
Description Mouse IgG monoclonal antibody for MAP2, microtubule-associated protein 2 (MAP2) detection. Tested with WB, IHC-P in Human;mouse;rat. No cross reactivity with other proteins.
Cite This Product Anti-MAP2 Antibody (Monoclonal, HM-2) HM-2 (Boster Biological Technology, Pleasanton CA, USA, Catalog # MA1057)
Replacement Item This antibody may replace the following items: sc-12012|sc-135979|sc-166773|sc-166826|sc-166827|sc-20172|sc-32791|sc-365204|sc-365637|sc-365959|sc-390543|sc-49450|sc-49451|sc-49452|sc-5357|sc-5359|sc-56561|sc-67234|sc-74419|sc-74420|sc-74421|sc-74422|sc-80012|sc-80013 from Santa Cruz Biotechnology.
Host Mouse
Isotype Mouse IgG1
Validated Species Human, Mouse, Rat
Application IHC-P, WB

*Our Boster Guarantee covers the use of this product in the above tested applications.

**For positive and negative control design, consult "Tissue specificity" under Protein Target Info.

Recommended Detection Systems Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P).
*Blocking peptide can be purchased at $50. Contact us for more information
**Boster also offers various secondary antibodies for Immunoflourescecne and IHC. Take advantage of the buy 1 primary antibody get 1 secondary antibody for free promotion for the entire year 2017!
Immunogen Rat brain microtubule-associated proteins(MAPs).
Cross Reactivity No cross reactivity with other proteins
Pack Size 100μg/vial

Properties

Clonality Monoclonal
Clone Number HM-2
Form Lyophilized
Contents Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
*carrier free antibody available upon request.
Concentration Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Storage At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
Purification Ascites
Isotype Mouse IgG1

Protein Target Info (Source: Uniprot.org)

You can check the tissue specificity below for information on selecting positive and negative control.

Gene Name Map2
Protein Name Microtubule-associated protein 2
Molecular Weight 202411 MW
Protein Function The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.
Sequence Similarities Contains 3 Tau/MAP repeats.
Subcellular Localization Cytoplasm, cytoskeleton .
Uniprot ID P15146
Alternative Names Microtubule-associated protein 2;MAP-2;Map2;Mtap2;
Research Areas |neuroscience|cell type marker|neuron marker|soma marker| signal transduction|cytoskeleton / ecm|cytoskeleton|microtubules|mt associated proteins|map| neuroscience|dendrite marker| stem cells|neural stem cells|neuron restricted lineage|
*if product is indicated to react with multiple species, protein info is based on the human gene.

Background for Microtubule-associated protein 2

MAP2, a 280-kD protein, is highly concentrated in neuronal somata and dendrites. Microtubule-associated protein 2(MAP2)is a neurosteroid receptor. MAP2 gene contains 19 exons, and located in segment 2q34-q35. The transgenic MAP2c was present in dendrites but not in axons but transgenic MAP2c messenger RNA was limited to cell bodies.

Anti-MAP2 Antibody (Monoclonal, HM-2) Images

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Anti-MAP2 Antibody (Monoclonal, HM-2)
Anti-MAP2 antibody (monoclonal), MA1057, IHC(P)
IHC(P): Rat Brain Tissue
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Publications

Song, S., Tan, J., Miao, Y., & Zhang, Q. (2017). Effect of different levels of intermittent hypoxia on autophagy of hippocampal neurons. Sleep and Breathing, 1-8. Advance online publication. doi:10.1007/s11325-017-1512-7
Ying Yang1, Nandan Wu1, Sijia Tian1, Fan Li1, Huan Hu1, Pei Chen1, Xiaoxiao Cai1, Lijun Xu1, Jing Zhang1, Zhao Chen1, Jian Ge1, Keming Yu1 and Jing Zhuang1 Lithium promotes DNA stability and survival of ischemic retinal neurocytes by upregulating DNA ligase IV Cell Death and Disease (2016) 7, e2473; doi:10.1038/cddis.2016.341
Tu Q, Pang L, Chen Y, Zhang Y, Zhang R, Lu B, Wang J. Analyst. 2014 Jan 7;139(1):105-15. Doi: 10.1039/C3An01796F. Epub 2013 Oct 25. Effects Of Surface Charges Of Graphene Oxide On Neuronal Outgrowth And Branching.
Chen Db, Feng L, Lin Xp, Zhang W, Li Fr, Liang Xl, Li Xh. Plos One. 2012;7(5):E37709. Doi: 10.1371/Journal.Pone.0037709. Epub 2012 May 21. Penicillamine Increases Free Copper And Enhances Oxidative Stress In The Brain Of Toxic Milk Mice.
Tu Q, Li L, Zhang Y, Wang J, Liu R, Li M, Liu W, Wang X, Ren L, Wang J. Biomaterials. 2011 Apr;32(12):3253-64. Doi: 10.1016/J.Biomaterials.2011.01.044. The Effect Of Acetylcholine-Like Biomimetic Polymers On Neuronal Growth.
Zhou Q, Zhang Q, Zhao X, Duan Yy, Lu Y, Li C, Li T. Brain Res. 2010 Jan 22;1311:148-57. Doi: 10.1016/J.Brainres.2009.11.022. Epub 2009 Nov 24. Cortical Electrical Stimulation Alone Enhances Functional Recovery And Dendritic Structures After Focal ...
Wang L, Luo J, Fang M, Jiang G, Zhang X, Yu W, Wang X. Synapse. 2012 Jun;66(6):533-41. Doi: 10.1002/Syn.21540. Epub 2012 Mar 16. A New Trick Of Inpp4A: Decreased Expression Of Inpp4A In Patients With Temporal Lobe Epilepsy And Pilocarpine-Induced ...
Zhao F, Hu Y, Zhang Y, Zhu Q, Zhang X, Luo J, Xu Y, Wang X. Synapse. 2012 Sep;66(9):781-91. Doi: 10.1002/Syn.21567. Epub 2012 May 23. Abnormal Expression Of Stathmin 1 In Brain Tissue Of Patients With Intractable Temporal Lobe Epilepsy And A Rat M...
Chen P, Hu H, Chen Z, Cai X, Zhang Z, Yang Y, Yu N, Zhang J, Xia L, Ge J, Yu K, Zhuang J. Plos One. 2014 Jun 11;9(6):E99371. Doi: 10.1371/Journal.Pone.0099371. Ecollection 2014. Brca1 Silencing Is Associated With Failure Of Dna Repairing In Retina...
Li Yy, Chen Xn, Fan Xx, Zhang Yj, Gu J, Fu Xw, Wang Zh, Wang Xf, Xiao Z. Synapse. 2015 Feb;69(2):67-77. Doi: 10.1002/Syn.21788. Epub 2014 Nov 11. Upregulated Dynamin 1 In An Acute Seizure Model And In Epileptic Patients.
Wang D, Ren M, Guo J, Yang G, Long X, Hu R, Shen W, Wang X, Zeng K. Plos One. 2014 Dec 23;9(12):E115801. Doi: 10.1371/Journal.Pone.0115801. Ecollection 2014. The Inhibitory Effects Of Npas4 On Seizures In Pilocarpine-Induced Epileptic Rats.
Wang X, Wei F, Liu A, Wang L, Wang Jc, Ren L, Liu W, Tu Q, Li L, Wang J. Biomaterials. 2012 May;33(14):3719-32. Doi: 10.1016/J.Biomaterials.2012.01.058. Epub 2012 Feb 18. Cancer Stem Cell Labeling Using Poly(L-Lysine)-Modified Iron Oxide Nanoparti...
Li L, Ren L, Liu W, Wang Jc, Wang Y, Tu Q, Xu J, Liu R, Zhang Y, Yuan Ms, Li T, Wang J. Anal Chem. 2012 Aug 7;84(15):6444-53. Doi: 10.1021/Ac3013708. Epub 2012 Jul 26. Spatiotemporally Controlled And Multifactor Involved Assay Of Neuronal Compartm...
Zhang Y, Xu Y, Zhu Q, Zhao F, Luo J, Zhang X, Wang X. Synapse. 2012 Jul;66(7):622-9. Doi: 10.1002/Syn.21548. Epub 2012 Mar 30. Upregulation Of Dysbindin In Temporal Lobe Epileptic Foci Of Human And Experimental Animals.
Cheng X, Li T, Zhou H, Zhang Q, Tan J, Gao W, Wang J, Li C, Duan Yy. Brain Res Bull. 2012 Nov 1;89(3-4):124-32. Doi: 10.1016/J.Brainresbull.2012.07.009. Epub 2012 Jul 28. Cortical Electrical Stimulation With Varied Low Frequencies Promotes Functio...
Xu Y, Luo J, Yue Z, Wu L, Zhang X, Zhou C, Zhao F, Wang X, Chen G. Brain Res. 2012 Jan 6;1429:124-33. Doi: 10.1016/J.Brainres.2011.10.008. Epub 2011 Oct 6. Increased Expression Of Placental Growth Factor In Patients With Temporal Lobe Epilepsy And...
Sun X, Jiang R, Zhang Y, Chen M, Xiang P, Qi Y, Gao Q, Huang B, Ge J. Mol Vis. 2009 Dec 2;15:2503-14. Gene Expression And Differentiation Characteristics In Mice E13.5 And E17.5 Neural Retinal Progenitors.
Luo J, Zeng K, Zhang C, Fang M, Zhang X, Zhu Q, Wang L, Wang W, Wang X, Chen G. Neurochem Res. 2012 Jul;37(7):1381-91. Doi: 10.1007/S11064-012-0712-6. Epub 2012 Feb 23. Down-Regulation Of Crmp-1 In Patients With Epilepsy And A Rat Model.
Wang Z, Chen Y, L?? Y, Chen X, Cheng L, Mi X, Xu X, Deng W, Zhang Y, Wang N, Li J, Li Y, Wang X. Neuroscience. 2015 Aug 6;300:314-24. Doi: 10.1016/J.Neuroscience.2015.05.008. Epub 2015 May 19. Effects Of Jip3 On Epileptic Seizures: Evidence From Te...
Li T, Mo X, Jiang Z, He W, Lu W, Zhang H, Zhang J, Zeng L, Yang B, Xiao H, Hu Z. Oxid Med Cell Longev. 2012;2012:945071. Doi: 10.1155/2012/945071. Epub 2012 Oct 12. Study Of ??b-Crystallin Expression In Gerbil Bcao Model Of Transient Global Cerebra...
Ge Xt, Lei P, Wang Hc, Zhang Al, Han Zl, Chen X, Li Sh, Jiang Rc, Kang Cs, Zhang Jn. Sci Rep. 2014 Oct 24;4:6718. Doi: 10.1038/Srep06718. Mir-21 Improves The Neurological Outcome After Traumatic Brain Injury In Rats.
Meng Xt, Chen D, Dong Zy, Liu Jm. Cell Biol Int. 2007 Jul;31(7):691-8. Epub 2007 Jan 19. Enhanced Neural Differentiation Of Neural Stem Cells And Neurite Growth By Amniotic Epithelial Cell Co-Culture.
Chen Y, Wei G, Nie H, Lin Y, Tian H, Liu Y, Yu X, Cheng S, Yan R, Wang Q, Liu Dh, Deng W, Lai Y, Zhou Jh, Zhang Sx, Lin Ww, Chen Df. Brain Res. 2014 Mar 13;1552:41-54. Doi: 10.1016/J.Brainres.2014.01.005. Epub 2014 Jan 20. ??-Asarone Prevents Autop...

FAQs

Q: Is your western blot protocol provided from the website applicable for all your antibodies? Keyword: applications, WB
A: The protocol is applicable for all our antibodies in WB, the NC Membrane(0.45μm or 0.22μm) and transfer time(70 mins or 50 mins) depends on the protein molecular weight, details can be found in included protocol.
Q: Can I conjugate markers to this antibody? Can I link custom conjugates to this antibody? Keyword: conjugation
A: The antibody is stored with BSA and cannot be conjugated with markers. Carrier free antibodies are available upon request. Please contact support@bosterbio.com
Q: Can you provide monoclonal antibodies carrier free?
A: We cannot.
Q: What are some alternative names that could be used to describe this product?
A: Some common names include but are not limited to map2 antibody, map 2 antibody, map-2 antibody