Anti-Mouse CD45.2 Monoclonal Antibody FITC Conjugated, Flow Validated

SKU FC00555-8-FITC
Size 25μg, 100μg, 500μg
Reactivity Mouse
Clonality Monoclonal
Clone Number 104
Host Mouse
Ig Isotype Mouse IgG2a, kappa
Applications Flow Cytometry

Overview

Product Name Anti-Mouse CD45.2 Monoclonal Antibody FITC Conjugated, Flow Validated
SKU/Catalog Number FC00555-8-FITC
Storage & Handling The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Size 25μg, 100μg, 500μg
Description Mouse IgG2a, kappa Monoclonal Anti-Mouse CD45.2 Antibody FITC Conjugated, Flow Validated
Cite This Product Anti-Mouse CD45.2 Monoclonal Antibody FITC Conjugated, Flow Validated (Boster Biological Technology, Pleasanton CA, USA, Catalog # FC00555-8-FITC)
Host Mouse
Contents/Buffer Phosphate-buffered aqueous solution, 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Form Liquid
Immunogen [immunogen]
Reactivity Mouse

Assay Details

Assay Dilutions Overview

Concentration: 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Flow Cytometry, 5μl per sample

Images And Assay Conditions

/F/C/FC00555 8 FITC flow cytometry test Anti Mouse CD45.2 FITC.jpg

C57BI/6 bone marrow cells were stained with FITC 104 with relevant isotype control in Red.

Target Info

Protein Target Info (Source: Uniprot.org)

Uniprot Id P06800
Gene Name Ptprc
Protein Name Receptor-type tyrosine-protein phosphatase C
Alternative Names Receptor-type tyrosine-protein phosphatase C;3.1.3.48;Leukocyte common antigen;L-CA;Lymphocyte antigen 5;Ly-5;T200;CD45;Ptprc;Ly-5;
Subcellular Localization Membrane; Single-pass type I membrane protein. Membrane raft . Colocalized with DPP4 in membrane rafts. .
Molecular Weight 144604 MW

*if product is indicated to react with multiple species, protein info is based on the human gene.

Ontology

Protein Function Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN (By similarity). Dephosphorylates LYN, and thereby modulates LYN activity. .
Research Areas Adapters, Adaptive Immunity, B Cells, Cell Type Markers, Immunology, Protein Phosphorylation, Signal Transduction, T Cells, Transmembrane, Tyrosine Phosphatases

*You can search these to find other products in these research areas.

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Publications

Isolation and morphological characterization of ovine amniotic fluid mesenchymal stem cells