Anti-NIPP1 PPP1R8 Antibody

NIPP1 antibody

Boster Bio Anti-NIPP1 PPP1R8 Antibody catalog # A05396-1. Tested in WB,IHC,IF applications. This antibody reacts with Human,Mouse,Rat.

Product Info Summary

SKU: A05396-1
Size: 100ul
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: IF, IHC, WB

Product Name

Anti-NIPP1 PPP1R8 Antibody

View all NIPP1 Antibodies

SKU/Catalog Number

A05396-1

Size

100ul

Form

Liquid

Description

Boster Bio Anti-NIPP1 PPP1R8 Antibody catalog # A05396-1. Tested in WB,IHC,IF applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-NIPP1 PPP1R8 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05396-1)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human CNG-1beta

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A05396-1 is reactive to PPP1R8 in Human, Mouse, Rat

Applications

A05396-1 is guaranteed for IF, IHC, WB Boster Guarantee

Observed Molecular Weight

111 kDa

Calculated molecular weight

38.479kDa

Background of NIPP1

Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis.

Beebe S.J., Mol. Endocrinol. 4:465-475(1990).
Gregory S.G., Nature 441:315-321(2006).
Wu K.-J., Oncogene 21:7872-7882(2002).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:2000
IHC/IF: 1:50-1:200

Validation Images & Assay Conditions

Gene/Protein Information For PPP1R8 (Source: Uniprot.org, NCBI)

Gene Name

PPP1R8

Full Name

Nuclear inhibitor of protein phosphatase 1

Weight

38.479kDa

Alternative Names

activator of RNA decay; ARD1; ard-1; ARD1nuclear inhibitor of protein phosphatase 1; NIPP1; NIPP1nuclear inhibitor of protein phosphatase-1; NIPP-1nuclear subunit of PP-1; PPP1R8; PRO2047; Protein phosphatase 1 regulatory inhibitor subunit 8; protein phosphatase 1 regulatory subunit 8; protein phosphatase 1, regulatory (inhibitor) subunit 8; RNase E PPP1R8 ARD-1, ARD1, NIPP-1, NIPP1, PRO2047 protein phosphatase 1 regulatory subunit 8 nuclear inhibitor of protein phosphatase 1|RNase E|activator of RNA decay|nuclear inhibitor of protein phosphatase-1 alpha|nuclear inhibitor of protein phosphatase-1 beta|nuclear subunit of PP-1|protein phosphatase 1, regulatory (inhibitor) subunit 8

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on PPP1R8, check out the PPP1R8 Infographic

PPP1R8 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for PPP1R8: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A05396-1-100ul

100ul

$405

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