Product Info Summary
SKU: | A03636-1 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-NLRP6 Antibody
SKU/Catalog Number
A03636-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-NLRP6 Antibody catalog # A03636-1. Tested in WB applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-NLRP6 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03636-1)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
A synthetic peptide of human NLRP6
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A03636-1 is reactive to Nlrp6 in Human, Mouse, Rat
Applications
A03636-1 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
97.402kDa
Background of NALP6
Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis By similarity. Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor: LRP6 during Wnt signaling (in vitro).
Benovic J.L., J. Biol. Chem. 268:19521-19527(1993).
Haribabu B., Proc. Natl. Acad. Sci. U.S.A. 90:9398-9402(1993).
Stoffel R.H., J. Biol. Chem. 269:27791-27794(1994).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of extracts of various cell lines, using NLRP6 antibody.
Protein Target Info & Infographic
Gene/Protein Information For Nlrp6 (Source: Uniprot.org, NCBI)
Gene Name
Nlrp6
Full Name
NACHT, LRR and PYD domains-containing protein 6
Weight
97.402kDa
Superfamily
NLRP family
Alternative Names
Angiotensin II/Vasopressin Receptor; AVR; CLR11.4; NACHT, Leucine Rich Repeat And PYD Containing 6; NACHT, LRR And PYD Containing Protein 6; NACHT, LRR And PYD Domains-Containing Protein 6; NALP6; NAVR; NAVR/AVR; NLR Family, Pyrin Domain Containing 6; NLRP6 ; NLRP6; Nucleotide-Binding Oligomerization Domain, Leucine Rich Repeat And Pyrin Domain Containing 6; PAN3; PYPAF5; PYRIN-Containing APAF1-Like Protein 5 Nlrp6|AI504961, Avr, N, Nalp6, Navr, Navr/Avr, Non-AVR, Pypaf5|NLR family, pyrin domain containing 6|NACHT, LRR and PYD domains-containing protein 6|NACHT, leucine rich repeat and PYD containing 6|NACHT/LRR/pyrin domain-containing protein 6|PYRIN-containing APAF1-like protein 5|angiotensin II/vasopressin receptor|non-angiotensin-vasopressin receptor
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Nlrp6, check out the Nlrp6 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Nlrp6: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-NLRP6 Antibody (A03636-1)
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No publications found for A03636-1
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