Anti-Glucocorticoid Receptor/NR3C1 Antibody Picoband™

NR3C1 antibody

Boster Bio Anti-Glucocorticoid Receptor/NR3C1 Antibody Picoband™ catalog # PB9232. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. Cited in 2 publication(s).

Product Info Summary

SKU: PB9232
Size: 100 μg/vial
Reactive Species: Human
Host: Rabbit
Application: Flow Cytometry, IF, IHC, ICC, WB

Product Name

Anti-Glucocorticoid Receptor/NR3C1 Antibody Picoband™

View all NR3C1 Antibodies

SKU/Catalog Number

PB9232

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Glucocorticoid Receptor/NR3C1 Antibody Picoband™ catalog # PB9232. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Glucocorticoid Receptor/NR3C1 Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # PB9232)

Host

Rabbit

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E.coli-derived human NR3C1 recombinant protein (Position: M1-D373). Human NR3C1 shares 85% and 82% amino acid (aa) sequences identity with mouse and rat NR3C1, respectively.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PB9232 is reactive to NR3C1 in Human

Applications

PB9232 is guaranteed for Flow Cytometry, IF, IHC, ICC, WB Boster Guarantee

Observed Molecular Weight

95 kDa

Calculated molecular weight

85.659kDa

Background of NR3C1

The glucocorticoid receptor (GR, or GCR), also known as NR3C1, is the receptor to which cortisol and other glucocorticoids bind. In humans, the GR protein is encoded by NR3C1 gene which is located on chromosome 5 (5q31). GR is expressed in almost every cell in the body and regulates genes controlling the development, metabolism, and immune response. Because the receptor gene is expressed in several forms, it has many different (pleiotropic) effects in different parts of the body. The activated GR complex up-regulates the expression of anti-inflammatory proteins in the nucleus or represses the expression of pro-inflammatory proteins in the cytosol (by preventing the translocation of other transcription factors from the cytosol into the nucleus).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Innovating Scientists Reward

If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.

Submit A Review

Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human
Immunohistochemistry (Paraffin-embedded Section), 2-5μg/ml, Human, By Heat
Immunocytochemistry/Immunofluorescence, 5μg/ml, Human
Flow Cytometry, 1-3μg/1x106 cells, Human

Validation Images & Assay Conditions

Gene/Protein Information For NR3C1 (Source: Uniprot.org, NCBI)

Gene Name

NR3C1

Full Name

Glucocorticoid receptor

Weight

85.659kDa

Superfamily

nuclear hormone receptor family

Alternative Names

GCR; glucocorticoid receptor; GR; GRGCCR; GRLNuclear receptor subfamily 3 group C member 1; NR3C1; nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor); nuclear receptor subfamily 3, group C, member 1 NR3C1 GCCR, GCR, GCRST, GR, GRL nuclear receptor subfamily 3 group C member 1 glucocorticoid receptor|glucocorticoid nuclear receptor variant 1|nuclear receptor subfamily 3 group C member 1 variant hGR-B(54)|nuclear receptor subfamily 3 group C member 1 variant hGR-B(77)|nuclear receptor subfamily 3 group C member 1 variant hGR-B(93)|nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on NR3C1, check out the NR3C1 Infographic

NR3C1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for NR3C1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

PB9232 has been cited in 2 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Lifen Ma,Xiaozhen Tan,Jiaqi Li,Yang Long,Zhen Xiao,Ji De,Yan Ren,Haoming Tian,T.a.o. Chen,A Novel Glucocorticoid Receptor Mutation in Primary Generalized Glucocorticoid Resistance Disease, Endocrine Practice, Volume 26,Issue 6,2020,651-659,ISSN 1530-891X,
Species: Human
PB9232 usage in article: APP:IF, SAMPLE:COS-7 CELL, DILUTION:NA

Sharma S, Maras JS, Das S, Hussain S, Mishra AK, Shasthry SM, Sharma CB, Weiss E, Elkrief L, Rautou PE, Gilgenkrantz H, Lotersztajn S, Paradis V, de la Grange P, Junot C0, Moreau R, Sarin SK. Sci Rep. 2017 Jul 28;7(1):6816. doi: 10.1038/s41598-017...

Have you used Anti-Glucocorticoid Receptor/NR3C1 Antibody Picoband™?

Submit a review and receive an Amazon gift card.

  • $25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
  • $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit A Review

Be the first to review Anti-Glucocorticoid Receptor/NR3C1 Antibody Picoband™

*The first user to submit a review for a product is eligible for Boster's Innovating Scientists Reward, which gives product credits. This is in addition to the gift card reward.

Have a question?

Find answers in Q&As, reviews.

Can't find your answer?

Submit your question

0 Customer Q&As for Anti-Glucocorticoid Receptor/NR3C1 Antibody Picoband™

Order DetailsPrice
PB9232

100μg

$370
PB9232-10ug

10μg sample (liquid)

$99
PB9232-Biotin

100 μg Biotin conjugated

$570
PB9232-Cy3

100 μg Cy3 conjugated

$570
PB9232-Dylight488

100 μg Dylight488 conjugated

$570
PB9232-Dylight550

100 μg Dylight550 conjugated

$570
PB9232-Dylight594

100 μg Dylight594 conjugated

$570
PB9232-FITC

100 μg FITC conjugated

$570
PB9232-HRP

100 μg HRP conjugated

$570
PB9232-APC

100 μg APC conjugated

$670
PB9232-PE

100 μg PE conjugated

$670
PB9232-carrier-free

Carrier Free

$370

More conjugates/formats

Free Secondary Antibody

Choose an option to show lead time.
Get A Quote
Eddy test
In stock
Order Product
PB9232
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

Troubleshooting

troubleshooting-box-image

Download troubleshooting handbooks for IHC, Western blot and ELISA for FREE.

Download Free PDFs Now

Boster Guarantee

Guaranteed product quality

Guaranteed product quality

We promise all of our products perform as described in datasheets.