Anti-p27 KIP 1/CDKN1B Antibody Picoband™

p27/Kip1 antibody

Boster Bio Anti-p27 KIP 1/CDKN1B Antibody Picoband™ catalog # PB9070. Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. Cited in 2 publication(s).

Product Info Summary

SKU: PB9070
Size: 100 μg/vial
Reactive Species: Human
Host: Rabbit
Application: Flow Cytometry, IF, ICC, WB

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Product Name

Anti-p27 KIP 1/CDKN1B Antibody Picoband™

View all p27/Kip1 Antibodies

SKU/Catalog Number

PB9070

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-p27 KIP 1/CDKN1B Antibody Picoband™ catalog # PB9070. Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-p27 KIP 1/CDKN1B Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # PB9070)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E.coli-derived human P27 KIP 1 recombinant protein (Position: S10-T198). Human P27 KIP 1 shares 87% amino acid (aa) sequence identity with mouse P27 KIP 1.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PB9070 is reactive to CDKN1B in Human

Applications

PB9070 is guaranteed for Flow Cytometry, IF, ICC, WB Boster Guarantee

Observed Molecular Weight

27 kDa

Calculated molecular weight

22.073kDa

Background of p27/Kip1

Cyclin-dependent kinase inhibitor 1B (p27KIP1), also known as KIP1 or P27, is an enzyme inhibitor that in humans is encoded by the CDKN1B gene. It encodes a protein which belongs to the Cip/Kipfamily of cyclin dependent kinase (Cdk) inhibitor proteins. It is mapped to 12p13.1. p27KIP1 can inhibit both CDK activation and the kinase activity of assembled and activated cyclin-CDK. The function of p27KIP1 is associated with an aggressive phenotype in human breast cancer. Downregulation of p27KIP1 by CK2-alpha-prime is necessary for development of agonist- and stress-induced cardiac hypertrophy.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human
Immunocytochemistry/Immunofluorescence, 5μg/ml, Human
Flow Cytometry, 1-3μg/1x106 cells, Human

Validation Images & Assay Conditions

Gene/Protein Information For CDKN1B (Source: Uniprot.org, NCBI)

Gene Name

CDKN1B

Full Name

Cyclin-dependent kinase inhibitor 1B

Weight

22.073kDa

Superfamily

CDI family

Alternative Names

CDKN1B; CDKN4; cyclin-dependent kinase inhibitor 1B (p27, Kip1); cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; Kip1; KIP1P27KIP1; MEN1B; MEN4; p27; p27Kip1 CDKN1B CDKN4, KIP1, MEN1B, MEN4, P27KIP1 cyclin dependent kinase inhibitor 1B cyclin-dependent kinase inhibitor 1B|cyclin-dependent kinase inhibitor 1B (p27, Kip1)

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on CDKN1B, check out the CDKN1B Infographic

CDKN1B infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for CDKN1B: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

PB9070 has been cited in 2 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Hepatitis B virus induces G1 phase arrest by regulating cell cycle genes in HepG2.2.15 cells

Li Bh, Xu Sb, Li F, Zou Xg, Saimaiti A, Simayi D, Wang Yh, Zhang Y, Yuan J, Zhang Wj. Cell Signal. 2012 Mar;24(3):718-25. Doi: 10.1016/J.Cellsig.2011.11.005. Epub 2011 Nov 13. Stat6 Activity-Related Th2 Cytokine Profile And Tumor Growth Advantage ...

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2 Customer Q&As for Anti-p27 KIP 1/CDKN1B Antibody Picoband™

Question

Has PB9070 been tested with IHC on prostate tissue?

Verified customer

Asked: 2020-12-23

Answer

Unfortunately, our lab hasn't tested the Anti-P27 KIP 1/CDKN1B Antibody Picoband™ (PB9070) with IHC on prostate tissue.

Boster Scientific Support

Answered: 2020-12-23

Question

We are currently using anti-p27 KIP 1/CDKN1B antibody PB9070 for human tissue, and we are content with the IF results. The species of reactivity given in the datasheet says human, rat. Is it true that the antibody can work on horse tissues as well?

Verified Customer

Verified customer

Asked: 2018-02-28

Answer

The anti-p27 KIP 1/CDKN1B antibody (PB9070) has not been validated for cross reactivity specifically with horse tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in horse you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2018-02-28

Order DetailsPrice
PB9070

100μg

$370
PB9070-10ug

10μg sample (liquid)

$99
PB9070-Biotin

100 μg Biotin conjugated

$570
PB9070-Cy3

100 μg Cy3 conjugated

$570
PB9070-Dylight488

100 μg Dylight488 conjugated

$570
PB9070-Dylight550

100 μg Dylight550 conjugated

$570
PB9070-Dylight594

100 μg Dylight594 conjugated

$570
PB9070-FITC

100 μg FITC conjugated

$570
PB9070-HRP

100 μg HRP conjugated

$570
PB9070-APC

100 μg APC conjugated

$670
PB9070-PE

100 μg PE conjugated

$670
PB9070-carrier-free

Carrier Free

$370

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Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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