Anti-PAK3 Antibody Picoband™

PAK3 antibody

Boster Bio Anti-PAK3 Antibody Picoband™ catalog # PB9877. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: PB9877
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: WB

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Product Name

Anti-PAK3 Antibody Picoband™

View all PAK3 Antibodies

SKU/Catalog Number

PB9877

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-PAK3 Antibody Picoband™ catalog # PB9877. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-PAK3 Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # PB9877)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human PAK3, identical to the related mouse and rat sequences.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

PB9877 is reactive to PAK3 in Human, Mouse, Rat

Applications

PB9877 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

62 kDa

Calculated molecular weight

62.31kDa

Background of PAK3

Serine/threonine-protein kinase PAK 3 is an enzyme that in humans is encoded by the PAK3 gene. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities. The protein encoded by this gene forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1 proteins which then catalyzes a variety of targets. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of non-syndromic mental retardation X-linked type 30 (MRX30), also called X-linked mental retardation type 47 (MRX47). Alternatively spliced transcript variants encoding different isoforms have been identified.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Mouse, Rat, Human

Validation Images & Assay Conditions

Gene/Protein Information For PAK3 (Source: Uniprot.org, NCBI)

Gene Name

PAK3

Full Name

Serine/threonine-protein kinase PAK 3

Weight

62.31kDa

Superfamily

protein kinase superfamily

Alternative Names

beta-PAK; bPAK; CDKN1A; EC 2.7.11; EC 2.7.11.1; hPAK3; mental retardation, X-linked 47; MRX30; MRX47; oligophrenin-3; OPHN3; p21 (CDKN1A)-activated kinase 3; p21 protein (Cdc42/Rac)-activated kinase 3; p21-activated kinase 3; PAK3; PAK-3; PAK3beta; serine/threonine-protein kinase PAK 3 PAK3 ARA, MRX30, MRX47, OPHN3, PAK-3beta, bPAK, beta-PAK, PAK3 p21 (RAC1) activated kinase 3 serine/threonine-protein kinase PAK 3|adriamycin resistance-associated|oligophrenin-3|p21 (CDKN1A)-activated kinase 3|p21 protein (Cdc42/Rac)-activated kinase 3

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on PAK3, check out the PAK3 Infographic

PAK3 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for PAK3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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3 Customer Q&As for Anti-PAK3 Antibody Picoband™

Question

We are currently using anti-PAK3 antibody PB9877 for rat tissue, and we are happy with the WB results. The species of reactivity given in the datasheet says human, mouse, rat. Is it likely that the antibody can work on dog tissues as well?

Verified Customer

Verified customer

Asked: 2020-04-09

Answer

The anti-PAK3 antibody (PB9877) has not been validated for cross reactivity specifically with dog tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in dog you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2020-04-09

Question

Does anti-PAK3 antibody PB9877 work for WB with middle temporal gyrus?

Verified Customer

Verified customer

Asked: 2020-03-26

Answer

According to the expression profile of middle temporal gyrus, PAK3 is highly expressed in middle temporal gyrus. So, it is likely that anti-PAK3 antibody PB9877 will work for WB with middle temporal gyrus.

Boster Scientific Support

Answered: 2020-03-26

Question

Is this PB9877 anti-PAK3 antibody reactive to the isotypes of PAK3?

Verified Customer

Verified customer

Asked: 2018-08-27

Answer

The immunogen of PB9877 anti-PAK3 antibody is A synthetic peptide corresponding to a sequence at the N-terminus of human PAK3 (13-49aa APPLRMNSNNRDSSALNHSSKPLPMAPEEKNKKARLR), identical to the related mouse and rat sequences. Could you tell me which isotype you are interested in so I can help see if the immunogen is part of this isotype?

Boster Scientific Support

Answered: 2018-08-27

Order DetailsPrice
PB9877

100μg

$370
PB9877-10ug

10μg sample (liquid)

$99
PB9877-Biotin

100 μg Biotin conjugated

$570
PB9877-Cy3

100 μg Cy3 conjugated

$570
PB9877-Dylight488

100 μg Dylight488 conjugated

$570
PB9877-Dylight550

100 μg Dylight550 conjugated

$570
PB9877-Dylight594

100 μg Dylight594 conjugated

$570
PB9877-FITC

100 μg FITC conjugated

$570
PB9877-HRP

100 μg HRP conjugated

$570
PB9877-APC

100 μg APC conjugated

$670
PB9877-PE

100 μg PE conjugated

$670
PB9877-carrier-free

Carrier Free

$370

More conjugates/formats

Free Secondary Antibody

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PB9877
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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