Anti-Phospho-4E-BP1 (T69) EIF4EBP1 Antibody

4EBP1 antibody

Boster Bio Anti-Phospho-4E-BP1 (T69) EIF4EBP1 Antibody catalog # A00968T69. Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse, Rat.

Product Info Summary

SKU: A00968T69
Size: 100ul
Reactive Species: Mouse, Rat
Host: Rabbit
Application: ELISA, IHC, WB

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Product Name

Anti-Phospho-4E-BP1 (T69) EIF4EBP1 Antibody

View all 4EBP1 Antibodies

SKU/Catalog Number

A00968T69

Size

100ul

Form

Liquid

Description

Boster Bio Anti-Phospho-4E-BP1 (T69) EIF4EBP1 Antibody catalog # A00968T69. Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Phospho-4E-BP1 (T69) EIF4EBP1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00968T69)

Host

Rabbit

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human 4E-BP1 around the phosphorylation site of T46.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A00968T69 is reactive to EIF4EBP1 in Mouse, Rat

Applications

A00968T69 is guaranteed for ELISA, IHC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

12.58kDa

Background of 4EBP1

4E-BP1 encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

Gingras AC, et al. (1998) Genes Dev 12(4): 502-513.
Brugarolas J, et al. (2004) Genes Dev 18(23): 2893-2904.
Kumar V, et al. (2000) EMBO J 19(5): 1087-1097.
Moody CA, et al. (2005) J Virol 79(9): 5499-5506.
Burnett PE, et al. (1998) Proc Natl Acad Sci U S A 95(4): 1432-1437.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:5000

Validation Images & Assay Conditions

Gene/Protein Information For EIF4EBP1 (Source: Uniprot.org, NCBI)

Gene Name

EIF4EBP1

Full Name

Eukaryotic translation initiation factor 4E-binding protein 1

Weight

12.58kDa

Superfamily

eIF4E-binding protein family

Alternative Names

4EBP1; 4E-BP1; eIF4E-binding protein 1; EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1,4EBP1,4E-BP1BP-1; eukaryotic translation initiation factor 4E-binding protein 1; PHAS-I; PHAS-IMGC4316; Phosphorylated heat- and acid-stable protein regulated by insulin 1 EIF4EBP1 4E-BP1, 4EBP1, BP-1, PHAS-I eukaryotic translation initiation factor 4E binding protein 1 eukaryotic translation initiation factor 4E-binding protein 1|eIF4E-binding protein 1|phosphorylated heat- and acid-stable protein regulated by insulin 1

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on EIF4EBP1, check out the EIF4EBP1 Infographic

EIF4EBP1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for EIF4EBP1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A00968T69-100ul

100ul

$380

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*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
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