Anti-E3 SUMO-protein ligase PIAS4 Antibody

PIASy antibody

Boster Bio Anti-E3 SUMO-protein ligase PIAS4 Antibody catalog # PA2215. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: PA2215
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: WB

Product Name

Anti-E3 SUMO-protein ligase PIAS4 Antibody

View all PIASy Antibodies

SKU/Catalog Number

PA2215

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-E3 SUMO-protein ligase PIAS4 Antibody catalog # PA2215. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-E3 SUMO-protein ligase PIAS4 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA2215)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human PIAS4, identical to the related mouse and rat sequences.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA2215 is reactive to PIAS4 in Human, Mouse, Rat

Applications

PA2215 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

57 kDa

Calculated molecular weight

56.504kDa

Background of PIASy

E3 SUMO-protein ligase PIAS4, also known as protein inhibitor of activated STAT protein 4 (PIAS4) or protein inhibitor of activated STAT protein gamma (PIASg or PIASy) is an enzyme that in humans is encoded by the PIAS4 gene. This gene is mapped to 19p13.3. This gene plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53/TP53 pathway, the Wnt pathway and the steroid hormone signaling pathway. It functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. This gene involved in gene silencing.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat

Validation Images & Assay Conditions

Gene/Protein Information For PIAS4 (Source: Uniprot.org, NCBI)

Gene Name

PIAS4

Full Name

E3 SUMO-protein ligase PIAS4

Weight

56.504kDa

Superfamily

PIAS family

Alternative Names

E3 SUMO-protein ligase PIAS4; FLJ12419; MGC35296; Piasg; PIAS-gamma; PIASY; Protein inhibitor of activated STAT protein 4; Protein inhibitor of activated STAT protein gamma; protein inhibitor of activated STAT protein PIASy; protein inhibitor of activated STAT, 4; zinc finger, MIZ-type containing 6; ZMIZ6 PIAS4 PIAS-gamma, PIASY, Piasg, ZMIZ6 protein inhibitor of activated STAT 4 E3 SUMO-protein ligase PIAS4|RING-type E3 ubiquitin transferase PIAS4|protein inhibitor of activated STAT protein 4|protein inhibitor of activated STAT protein PIASy|protein inhibitor of activated STAT protein gamma|zinc finger, MIZ-type containing 6

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on PIAS4, check out the PIAS4 Infographic

PIAS4 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for PIAS4: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
PA2215

100μg

$370
PA2215-10ug

10μg sample (liquid)

$99
PA2215-Biotin

100 μg Biotin conjugated

$570
PA2215-Cy3

100 μg Cy3 conjugated

$570
PA2215-Dylight488

100 μg Dylight488 conjugated

$570
PA2215-Dylight550

100 μg Dylight550 conjugated

$570
PA2215-Dylight594

100 μg Dylight594 conjugated

$570
PA2215-FITC

100 μg FITC conjugated

$570
PA2215-HRP

100 μg HRP conjugated

$570
PA2215-APC

100 μg APC conjugated

$670
PA2215-PE

100 μg PE conjugated

$670
PA2215-carrier-free

Carrier Free

$370

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PA2215
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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