Product Info Summary
SKU: | A04226-1 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IHC, WB |
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Product info
Product Name
Anti-PLC Beta 3 (D1099) PLCB3 Antibody
View all PLC-beta 3 Antibodies
SKU/Catalog Number
A04226-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-PLC Beta 3 (D1099) PLCB3 Antibody catalog # A04226-1. Tested in WB,IHC applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-PLC Beta 3 (D1099) PLCB3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04226-1)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from internal of human LTK.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A04226-1 is reactive to PLCB3 in Human, Mouse, Rat
Applications
A04226-1 is guaranteed for IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
138.799kDa
Background of PLC-beta 3
Orphan receptor with a tyrosine-protein kinase activity. The exact function of this protein is not known. Studies with chimeric proteins (replacing its extracellular region with that of several known growth factor receptors, such as EGFR and CSFIR) demonstrate its ability to promote growth and specifically neurite outgrowth, and cell survival. Signaling appears to involve the PI3 kinase pathway. Involved in regulation of the secretory pathway involving endoplasmic reticulum (ER) export sites (ERESs) and ER to Golgi transport.
Toyoshima H., Proc. Natl. Acad. Sci. U.S.A. 90:5404-5408(1993).
Krolewski J.J., EMBO J. 10:2911-2919(1991).
Maru Y., Oncogene Res. 5:199-204(1990).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:1000
IHC: 1:50-1:200
Validation Images & Assay Conditions
Click image to see more details
Figure 2. Immunohistochemistry validation of PLCB3 using Anti-PLC Beta 3 (D1099) PLCB3 Antibody (A04226-1).
Immunohistochemistry (IHC) analyzes of PLC β3 (D1099) pAb in paraffin-embedded human breast carcinoma tissue at 1:50.For more protocol information of IHC
Click image to see more details
Figure 1. Western blotting validation for Anti-PLC Beta 3 (D1099) PLCB3 Antibody A04226-1
Western blot (WB) analysis of PLC β3 (D1099) polyclonal antibody at 1:500 dilutionLane1:CT-26 whole cell lysate(40ug)
Lane2:PC12 whole cell lysate(40ug)
Lane3:HEK293T whole cell lysate(40ug)
Lane4:Hela whole cell lysate(40ug)
Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For PLCB3 (Source: Uniprot.org, NCBI)
Gene Name
PLCB3
Full Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
Weight
138.799kDa
Alternative Names
1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3; EC 3.1.4.11; FLJ37084; Phosphoinositide phospholipase C-beta-3; phospholipase C, beta 3 (phosphatidylinositol-specific); Phospholipase C-beta-3; PLC beta 3; PLCB3; PLCbeta 3; PLC-beta 3; PLC-beta-3 PLCB3 SMDCD phospholipase C beta 3 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3|PLC beta 3|phosphoinositide phospholipase C-beta-3|phospholipase C, beta 3 (phosphatidylinositol-specific)
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PLCB3, check out the PLCB3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for PLCB3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-PLC Beta 3 (D1099) PLCB3 Antibody (A04226-1)
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No publications found for A04226-1
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