SKU A30715
Size 100ug/vial
Reactivity Human
Clonality Polyclonal
Host Rabbit
Applications IF, IHC, WB

Overview

Product Name Anti-RAD Antibody
SKU/Catalog Number A30715
Storage & Handling At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.
Size 100ug/vial
Description Anti-RAD Antibody
Cite This Product Anti-RAD Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A30715)
Host Rabbit
Contents/Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form Liquid
Immunogen A peptide derived from human RAD. Immunogen sequence location: 41-90
Reactivity Human

Assay Details

Assay Dilutions Overview

Concentration: 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
User need to optimize the dilution ratio for this antibody

Images And Assay Conditions

/R/A/RAD primary antibodies A30715 WB testing.jpg

Western blot analysis of lysates from HeLa and HepG2/MCF-7 cells, using RAD Antibody. The lane on the right is blocked with the synthesized peptide.

/R/A/RAD primary antibodies A30715 IHC testing.jpg

Immunohistochemistry analysis of paraffin-embedded human heart tissue, using RAD Antibody. The picture on the right is blocked with the synthesized peptide.

/R/A/RAD primary antibodies A30715 IF testing.jpg

Immunofluorescence analysis of A549 cells, using RAD Antibody. The picture on the right is blocked with the synthesized peptide.

Target Info

Protein Target Info (Source: Uniprot.org)

Uniprot Id P55042
Gene Name RRAD
Protein Name GTP-binding protein RAD
Tissue Specificity Most abundantly expressed in the heart. Also found in the skeletal muscle and lung. Lesser amounts in placenta and kidney. Also detected in adipose tissue. Overexpressed in muscle of type II diabetic humans. .
Alternative Names GTP-binding protein RAD;RAD1;Ras associated with diabetes;RRAD;RAD;
Subcellular Localization Cell membrane .
Molecular Weight 33245 MW

*if product is indicated to react with multiple species, protein info is based on the human gene.

Ontology

Protein Function May play an important role in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca(2+) currents. Regulates voltage-dependent L-type calcium channel subunit alpha- 1C trafficking to the cell membrane (By similarity). Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway. Inhibits phosphorylation and activation of CAMK2D. .
Research Areas Cardiovascular, G Protein Signaling, Hypertrophy, Signal Transduction, Signaling Pathway, Small G Proteins

*You can search these to find other products in these research areas.

Other Recommended Resources

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Order Product (A30715)

Promotion:

Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
Option Price
100ug $299
100ug+Free HRP Secondary BA1054 $299
100ug+Free Biotin Secondary BA1003 $299

USD $299

Ships in 7-10 business days.

Troubleshooting

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