|Applications||IF, IHC, WB|
|Product Name||Anti-RAD Antibody|
|Storage & Handling||At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.|
|Cite This Product||Anti-RAD Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A30715)|
|Contents/Buffer||Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|Immunogen||A peptide derived from human RAD. Immunogen sequence location: 41-90|
Assay Dilutions Overview
User need to optimize the dilution ratio for this antibody
Images And Assay Conditions
Western blot analysis of lysates from HeLa and HepG2/MCF-7 cells, using RAD Antibody. The lane on the right is blocked with the synthesized peptide.
Immunohistochemistry analysis of paraffin-embedded human heart tissue, using RAD Antibody. The picture on the right is blocked with the synthesized peptide.
Immunofluorescence analysis of A549 cells, using RAD Antibody. The picture on the right is blocked with the synthesized peptide.
Protein Target Info (Source: Uniprot.org)
|Protein Name||GTP-binding protein RAD|
|Tissue Specificity||Most abundantly expressed in the heart. Also found in the skeletal muscle and lung. Lesser amounts in placenta and kidney. Also detected in adipose tissue. Overexpressed in muscle of type II diabetic humans. .|
|Alternative Names||GTP-binding protein RAD;RAD1;Ras associated with diabetes;RRAD;RAD;|
|Subcellular Localization||Cell membrane .|
|Molecular Weight||33245 MW|
*if product is indicated to react with multiple species, protein info is based on the human gene.
|Protein Function||May play an important role in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca(2+) currents. Regulates voltage-dependent L-type calcium channel subunit alpha- 1C trafficking to the cell membrane (By similarity). Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway. Inhibits phosphorylation and activation of CAMK2D. .|
*You can search these to find other products in these research areas.
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