Anti-RMP URI1 Antibody

URI antibody

Boster Bio Anti-RMP URI1 Antibody (Catalog # A05245). Tested in WB, IHC applications. This antibody reacts with Human, Mouse.

Product Info Summary

SKU: A05245
Size: 100 µl
Reactive Species: Human, Mouse
Host: Rabbit
Application: IHC, WB

Customers Who Bought This Also Bought

Product Name

Anti-RMP URI1 Antibody

View all URI Antibodies

SKU/Catalog Number

A05245

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-RMP URI1 Antibody (Catalog # A05245). Tested in WB, IHC applications. This antibody reacts with Human, Mouse.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-RMP URI1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05245)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from C-terminal of human RMP.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A05245 is reactive to URI1 in Human, Mouse

Applications

A05245 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

111 kDa

Calculated molecular weight

59.832kDa

Background of URI

Involved in gene transcription regulation. Acts as a transcriptional repressor in concert with the corepressor UXT to regulate androgen receptor (AR) transcription. May act as a tumor suppressor to repress AR-mediated gene transcription and to inhibit anchorage-independent growth in prostate cancer cells. Required for cell survival in ovarian cancer cells. Together with UXT, associates with chromatin to the NKX3-1 promoter region. Antagonizes transcriptional modulation via hepatitis B virus X protein. Plays a central role in maintaining S6K1 signaling and BAD phosphorylation under normal growth conditions thereby protecting cells from potential deleterious effects of sustained S6K1 signaling. The URI1-PPP1CC complex acts as a central component of a negative feedback mechanism that counteracts excessive S6K1 survival signaling to BAD in response to growth factors. Mediates inhibition of PPP1CC phosphatase activity in mitochondria. Coordinates the regulation of nutrient-sensitive gene expression availability in a mTOR-dependent manner. Seems to be a scaffolding protein able to assemble a prefoldin-like complex that contains PFDs and proteins with roles in transcription and ubiquitination.

Van Leuven F., Genomics 54:511-520(1998).
Ota T., Nat. Genet. 36:40-45(2004).
Grimwood J., Nature 428:529-535(2004).<

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Innovating Scientists Reward

If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.

Submit A Review

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Validation Images & Assay Conditions

Gene/Protein Information For URI1 (Source: Uniprot.org, NCBI)

Gene Name

URI1

Full Name

Unconventional prefoldin RPB5 interactor 1

Weight

59.832kDa

Superfamily

RNA polymerase II subunit 5-mediating protein family

Alternative Names

chromosome 19 open reading frame 2; FLJ10575; NNX3RPB5-mediating protein; Protein NNX3; RMPunconventional prefoldin RPB5 interactor; RNA polymerase II subunit 5-mediating protein; URIRNA polymerase II, subunit 5-mediating protein URI1 C19orf2, NNX3, PPP1R19, RMP, URI URI1 prefoldin like chaperone unconventional prefoldin RPB5 interactor 1|RNA polymerase II subunit 5-mediating protein|RPB5-mediating protein|protein phosphatase 1, regulatory subunit 19

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on URI1, check out the URI1 Infographic

URI1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for URI1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

No publications found for A05245

*Do you have publications using this product? Share with us and receive a reward. Ask us for more details.

Have you used Anti-RMP URI1 Antibody?

Submit a review and receive an Amazon gift card.

  • $25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
  • $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit A Review

Be the first to review Anti-RMP URI1 Antibody

*The first user to submit a review for a product is eligible for Boster's Innovating Scientists Reward, which gives product credits. This is in addition to the gift card reward.

Have a question?

Find answers in Q&As, reviews.

Can't find your answer?

Submit your question

3 Customer Q&As for Anti-RMP URI1 Antibody

Question

I was wanting to use your anti-RMP antibody for IHC for human cervix carcinoma on frozen tissues, but I want to know if it has been tested for this particular application. Has this antibody been tested and is this antibody a good choice for human cervix carcinoma identification?

Verified Customer

Verified customer

Asked: 2020-02-03

Answer

You can see on the product datasheet, A05245 anti-RMP antibody has been validated for IHC, WB on human, mouse tissues. We have an innovator award program that if you test this antibody and show it works in human cervix carcinoma in IHC-frozen, you can get your next antibody for free.

Boster Scientific Support

Answered: 2020-02-03

Question

We are currently using anti-RMP antibody A05245 for human tissue, and we are well pleased with the IHC results. The species of reactivity given in the datasheet says human, mouse. Is it likely that the antibody can work on canine tissues as well?

Verified Customer

Verified customer

Asked: 2018-10-16

Answer

The anti-RMP antibody (A05245) has not been tested for cross reactivity specifically with canine tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in canine you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2018-10-16

Question

I am interested in to test anti-RMP antibody A05245 on human cervix carcinoma for research purposes, then I may be interested in using anti-RMP antibody A05245 for diagnostic purposes as well. Is the antibody suitable for diagnostic purposes?

C. Zhang

Verified customer

Asked: 2014-06-09

Answer

The products we sell, including anti-RMP antibody A05245, are only intended for research use. They would not be suitable for use in diagnostic work. If you have the means to develop a product into diagnostic use, and are interested in collaborating with us and develop our product into an IVD product, please contact us for more discussions.

Boster Scientific Support

Answered: 2014-06-09

Order DetailsPrice
A05245-100uL

100uL

$360

Free Secondary Antibody

Choose an option to show lead time.
Get A Quote
Eddy test
In stock
Order Product
A05245
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$360.00

Troubleshooting

troubleshooting-box-image

Download troubleshooting handbooks for IHC, Western blot and ELISA for FREE.

Download Free PDFs Now

Boster Guarantee

Guaranteed product quality

Guaranteed product quality

We promise all of our products perform as described in datasheets.