Product Info Summary
SKU: | A08776-1 |
---|---|
Size: | 100ul |
Reactive Species: | Human |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-RNA-binding protein 6 RBM6 Antibody
SKU/Catalog Number
A08776-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-RNA-binding protein 6 RBM6 Antibody catalog # A08776-1. Tested in WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-RNA-binding protein 6 RBM6 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08776-1)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from internal of human RNUXA.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A08776-1 is reactive to RBM6 in Human
Applications
A08776-1 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
128.644kDa
Background of RBM6
A phosphoprotein adapter involved in the XPO1-mediated U snRNA export from the nucleus. Bridge components required for U snRNA export, the cap binding complex (CBC)-bound snRNA on the one hand and the GTPase Ran in its active GTP-bound form together with the export receptor XPO1 on the other. Its phosphorylation in the nucleus is required for U snRNA export complex assembly and export, while its dephosphorylation in the cytoplasm causes export complex disassembly. It is recycled back to the nucleus via the importin alpha/beta heterodimeric import receptor. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Its compartmentalized phosphorylation cycle may also contribute to the directionality of export. Binds strongly to m7G-capped U1 and U5 small nuclear RNAs (snRNAs) in a sequence-unspecific manner and phosphorylation-independent manner By similarity. Plays also a role in the biogenesis of U3 small nucleolar RNA (snoRNA). Involved in the U3 snoRNA transport from nucleoplasm to Cajal bodies. Binds strongly to m7G-capped U3, U8 and U13 precursor snoRNAs and weakly to trimethylated (TMG)-capped U3, U8 and U13 snoRNAs. Binds also to telomerase RNA.
Ota T., Nat. Genet. 36:40-45(2004).
Ebert L., Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Boulon S., Mol. Cell 16:777-787(2004).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For RBM6 (Source: Uniprot.org, NCBI)
Gene Name
RBM6
Full Name
RNA-binding protein 6
Weight
128.644kDa
Alternative Names
DEF-3; DEF3FLJ39446,3G2; DKFZp686B0877; FLJ36517; FLJ42036; g16; HLC-11; Lung cancer antigen NY-LU-12; lung cancer protooncogene 11; NY-LU-12; Protein G16; RNA binding motif protein 6; RNA-binding motif protein 6; RNA-binding protein 6; RNA-binding protein DEF-3 RBM6 3G2, DEF-3, DEF3, HLC-11, NY-LU-12, g16 RNA binding motif protein 6 RNA-binding protein 6|RNA-binding protein DEF-3|lung cancer antigen NY-LU-12|lung cancer protooncogene 11
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on RBM6, check out the RBM6 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for RBM6: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-RNA-binding protein 6 RBM6 Antibody (A08776-1)
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