Anti-RNA-binding protein 6 RBM6 Antibody

RBM6 antibody

Boster Bio Anti-RNA-binding protein 6 RBM6 Antibody catalog # A08776-1. Tested in WB applications. This antibody reacts with Human.

Product Info Summary

SKU: A08776-1
Size: 100ul
Reactive Species: Human
Host: Rabbit
Application: WB

Product Name

Anti-RNA-binding protein 6 RBM6 Antibody

View all RBM6 Antibodies

SKU/Catalog Number

A08776-1

Size

100ul

Form

Liquid

Description

Boster Bio Anti-RNA-binding protein 6 RBM6 Antibody catalog # A08776-1. Tested in WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-RNA-binding protein 6 RBM6 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08776-1)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human RNUXA.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A08776-1 is reactive to RBM6 in Human

Applications

A08776-1 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

128.644kDa

Background of RBM6

A phosphoprotein adapter involved in the XPO1-mediated U snRNA export from the nucleus. Bridge components required for U snRNA export, the cap binding complex (CBC)-bound snRNA on the one hand and the GTPase Ran in its active GTP-bound form together with the export receptor XPO1 on the other. Its phosphorylation in the nucleus is required for U snRNA export complex assembly and export, while its dephosphorylation in the cytoplasm causes export complex disassembly. It is recycled back to the nucleus via the importin alpha/beta heterodimeric import receptor. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Its compartmentalized phosphorylation cycle may also contribute to the directionality of export. Binds strongly to m7G-capped U1 and U5 small nuclear RNAs (snRNAs) in a sequence-unspecific manner and phosphorylation-independent manner By similarity. Plays also a role in the biogenesis of U3 small nucleolar RNA (snoRNA). Involved in the U3 snoRNA transport from nucleoplasm to Cajal bodies. Binds strongly to m7G-capped U3, U8 and U13 precursor snoRNAs and weakly to trimethylated (TMG)-capped U3, U8 and U13 snoRNAs. Binds also to telomerase RNA.

Ota T., Nat. Genet. 36:40-45(2004).
Ebert L., Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Boulon S., Mol. Cell 16:777-787(2004).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:2000

Validation Images & Assay Conditions

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Gene/Protein Information For RBM6 (Source: Uniprot.org, NCBI)

Gene Name

RBM6

Full Name

RNA-binding protein 6

Weight

128.644kDa

Alternative Names

DEF-3; DEF3FLJ39446,3G2; DKFZp686B0877; FLJ36517; FLJ42036; g16; HLC-11; Lung cancer antigen NY-LU-12; lung cancer protooncogene 11; NY-LU-12; Protein G16; RNA binding motif protein 6; RNA-binding motif protein 6; RNA-binding protein 6; RNA-binding protein DEF-3 RBM6 3G2, DEF-3, DEF3, HLC-11, NY-LU-12, g16 RNA binding motif protein 6 RNA-binding protein 6|RNA-binding protein DEF-3|lung cancer antigen NY-LU-12|lung cancer protooncogene 11

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on RBM6, check out the RBM6 Infographic

RBM6 infographic

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In this infographic, you will see the following information for RBM6: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A08776-1-100ul

100ul

$405

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